NPR

Scientists Find Brain Cells That Make Pain Hurt

Researchers have pinpointed the neurons that give pain its unpleasant edge. By turning these neurons off in mice, the scientists relieved the unpleasantness of pain without numbing sensation.
Researchers studying mouse brains identified the cells that encode pain's unpleasantness.

Pain is a complicated experience. Our skin and muscles sense it, just like they sense softness or warmth. But unlike other sensations, the experience of pain is distinctly unpleasant.

Pain has to hurt for us to pay attention to it, and avoid hurting ourselves further.

But for people in chronic pain, the pain has largely lost its purpose. It just hurts.

While it has long been understood how nerves signal pain to the brain, scientists haven't known how the brain adds a layer of unpleasantness.

Findings of in offer an answer.

You’re reading a preview, subscribe to read more.

More from NPR

NPR3 min read
Bearing Witness, Celebrating Strength: How Poetry Has Changed Lives For NPR's Audience
From sparking the imagination to helping with mental health, listen to poems read by NPR readers and see how poetry has affected their lives.
NPR3 min readAmerican Government
Who Is Hope Hicks, The Former Trump Adviser Testifying In New York Criminal Trial?
Hope Hicks was a communications director for the Trump White House and prosecutors may question her on her knowledge of the deals made during his first presidential run.
NPR3 min read
Scientists Welcome New Rules On Marijuana, But Research Will Still Face Obstacles
When marijuana becomes a Schedule III instead of a Schedule I substance under federal rules, researchers will face fewer barriers to studying it. But there will still be some roadblocks for science.

Related Books & Audiobooks