RADIONUCLIDE RENOGRAPHY

Bachelors in Medical Imaging Technology

Introduction
Kidneys are responsible for 3 major functions;
Regulatory Maintenance of acid-base balance, pH, blood volume, electrolytes Endocrine Secretion and activation of hormones Excretory Glomerular filtration, active tubular filtration and reabsorption.

Radiopharmaceuticals
Can be classified in 3:a) Those excreted by Glomerular filtration
a) Tc99m DTPA b) Cr51 EDTA c) Tc99m MDP

b) Those excreted by tubular secretion

a) I123 and I131 OIH b) Tc99m MAG3 c) Tc99m L,L and D,D EC

c) Those retained in renal tubules for long

a) Tc99m DMSA b) Tc99m GH (both retention & GFR)
CLINICAL NUCLEAR MEDICINE Hans Jurgen, Leonard M. Pg.172

Cont.
The radiopharmaceuticals eliminated by the kidneys help to evaluate renal function and urinary drainage. Those retained by the renal parenchyma are termed as cortical agents and help to assess renal mass distribution.

RADIOLOGICAL IMAGING OF THE KIDNEYS Emilio Quaia. Pg.231

Tc99m DTPA
Diethylene triamine pentaacetic acid

99mTechnetium 51Chromium

Cr51 EDTA
Ethylene diamine triacetic acid

Tc99m MDP
Methylene diphosphate

99mTechnetium
123, 131Iodine

I123 and I131 OIH

Orhtoiodohippurate

Tc99m MAG3
Mercaptoacetyltriglycine
ethylenedicysteine Dimercaptosuccinic acid Glucoheptonate

99mTechnetium
99mTechnetium 99mTechnetium 99mTechnetium

Tc99m L,L and D,D EC Tc99m DMSA Tc99m GH

Principle investigations
Blood sampling