Generic Name Brand Name Classification Indication Co ntraindication MechanismOf ActionAdverse Reaction Nu rsing ConsiderationsPer 1.

2 g vialCoamoxiclav:Amoxicillin 1g &clavulanicacid 200 mgAmoclav BactericidalLower resp tractinfections, otitismedia, sinusitis,skin & soft tissueinfections, UTI, pre&

post-surgical procedures, bone & joint, O & Ginfections, dentalinfections.History of penicillinhypersensitivity.Su perinfectionsinvolvingPseud omonas or candida. Pregnancy& lactationInhibits enzymes involved information of peptidoglycan layer of bacterial cell wall No effect on human cell

wallsBactericidal; only works ondividing bacteriaWell absorbed enterallyClavulanic acid inhibits bacteriallactamaseAllergic reactionsitching, rashes, fever angioneuroticoedemaanaphylaxis (1 in 50,000to 100,000)Cross-allergy with other penicillinsPartial cross-allergy withcephalosporins

(10%)Hepatitis, cholestatic jaundiceErythem a multiforme(including Stevens-Johnson)Toxic epidermalnecrolysis; exfoliativedermatitisDiarrhe a, vomitingRashes Neutropeni aAnaemiaPregnancyHistory of hypersensitivityRenal impairmentHepatic impairment - maycause cholestatic jaundiceup to 6

weeks after cessationMay cause maculopapular rashes - almost always in presence of glandular fever Generic Name Brand NameClassification Indicati on Contraindication Mechan ismOf ActionAdverse Reaction Nu rsing Considerations