AIIMS November 2006 Biochemistry

1. Defect in alpha 5 of typeIV collagen seen in ?

A. Alport's syndrome
B. Thin membrane disease

Ans. Alport's syndrome

Explanation: Alport's syndrome has defect in alpha 5 where as Thin

membrane has defect in alpha 4.

2. Where does glucocorticoids bind in the DNA receptor site ?

A. Zinc finger motiff
B. Leucine zipper motiff
C. Helix turn helix motiff

Ans. Zinc finger motiff

3. The function of cellular cytochrome C is ?

A. Apoptosis
B. Cell Necrosis
C. Electron transport

Ans. ?Apoptosis

4. Amyloid beta pleated sheets ?

A. Scanning electron microscopy
B. X-ray crystallography
C. Apple green florescence in congo red staining
D. Polarizing electron microscope

Ans. X-ray crystallography

5. Genetic code is ?
A. Degenerate

Ans. Degenerate

6. Which of the following agent is used to send a blood sample for estimation
of blood glucose level ?
A. E. D. T. A
B. Potassium – oxalate
C. K – oxalate + NaF
 D. K – oxalate + NaI

Ans. K - oxalate + NaF

7. There is distance of 40nm between 2 fibrils of collagen linked by 1 of the

following and it acts as a site of calcium deposition, it is ?
A. Fe
B. Protein
C. Carbohydrate
D. Zn
intensity of light Ans—B

AIIMS NOV 2007

2.

36. Peroxidase is used to detect:

a. Glucose
b. Ammonia
c. Hemoglobin
d. Creatinine Ans—C
37. For biochemical analysis vitrous in sent in:
a. Hydrochloric acid
b. Phenol / xylol
c. Formalin
d. Fluoride Ans—D
38. Blood spills on the floor are cleaned by:
a. Sodium hypochlorite
b. Iodine
c. Absolute alcohol
d. Quarternary ammonium compounds Ans—A
39. PCR requires:
a. Li++
b. Ca++
c. Na++
d. Mg++ Ans--D
40. In Lysosomal Storage Disorders, true is:
a. The lysosomes are deficient in the enzyme hydrolase
b. There is a defect in the fusion od lysosomes and phagosomes
c. There is a defect in the lysosomal membrane
d. .. Ans—A
41. Vitamin K is required for:
a. Carboxylation
b. Hydroxylation
c. ..
d. .. Ans—A
42. Proteins which are different in peptide sequence but have a similar structure in the process of
evolution are said to be:
a. Convergent
b. Divergent
c. Opportunistic
d. Incidental Ans—A
43. Hemoglobin estimation is not done by:
a. Drabkin’s method
b. Sahli’s method
c. Spectrometry
d. Wintrobe’s method Ans—D
44. Nephelometry is:
a. Lambert-Beer law
b. Scattering of light by particulate solution
c. Defraction of light
d. Decreased