Name:______________________________ _ Class: ________ Date: _____________ Genetics and DNA Review with the iPad

Introduction: You will be using the iPads to review basic principles of genetics and DNA. Most of this activity will require the use of the app Gene Screen, which is already installed on your iPad. Directions:

1. Open the application Gene Screen by tapping on the icon. 2. Complete each section of the worksheet by using the following sections of the application.
Section 1: Learn About Genetics: Genes and Inheritance

1. Which cells lack a nucleus? 2. How many chromosomes are found in the nucleus of human cells? 3. How do females and males differ on the chromosomal level? 4. Which DNA bases pair together? 5. What is a gene? 6. What is a mutation? 7. How many chromosomes does a human offspring inherit from his father and mother? 8. How is it possible for a person to inherit one copy of a mutated gene and not express the disease? EXPLAIN

9. What does a Punnett square show?

Use the home icon to return to the main screen

2012 Jeremy Conn Page 1/4

Section 2: Learn About Genetics: Population Genetics

10. Do all mutations cause disease? EXPLAIN

11. What is the founder effect?

12. Which people groups provide examples of the founder effect? 13. Which genetic diseases are more common in the Amish?
Use the home icon to return to the main screen Section 3: Learn About Genetics: Recessive Genetic Diseases

14. Pick any two recessive genetic diseases. Fill out the chart below for each disease. Disease Name

Prevelance

Symptoms

Genetic diagnosis

treatment

Use the home icon to return to the main screen

2012 Jeremy Conn Page 2/4

Section 4: Learn About Genetics: Genetic Screening

15. What can a genetic test determine?

16. What is the purpose of genetic screening?

17. What is the chance of two carriers have an offspring with the recessive condition? 18. What have screening programs done to the incidence rates of certain genetic diseases?

Use the home icon to return to the main screen Section 5: Inheritance Calculators: Genetic Traits

19. What is the chance of two parents with the following genotypes having a child with a straight hairline?
a. TT x Tt b. Tt x tt c. Tt x Tt

Section 6: Inheritance Calculators: Genetic Diseases

20. What is the chance a child will have a recessive genetic disease in each of the following scenarios?
a. unaffected father & affected mother b. carrier mother & affected father

2012 Jeremy Conn Page 3/4

Section 6: Map of Genetic Diseases

21. For each of the following diseases below, describe in which regions and/or people groups they are most prevalent. Tap on the By disease icon. Tap on Reset to choose another disease. a. Wilson Disease b. Bloom syndrome c. Beta-Thalassemia d. Cystic Fibrosis e. Maple Syrup Urine Disease f. Tay-Sachs Disease g. Spinal Muscular Atrophy h. Werner Syndrome

2012 Jeremy Conn Page 4/4