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#584961 borderline - 05/09/11 14:33 1 I do not know (C is wrong for sure) 2A 3 I do not know (B is wrong for sure), may

be E because the doctor should be sure that his patient want to quite before giving him advices ?? who knows?? 4 D (selectin loose binding on endothelial cells.. See FA pathology section) 5 F (riketssia Rx tetracycline) 6E 7 B (horner syndrome) 8 B (avascular necrosis--medial femoral circumflex = memorisation) 9 C (why not anticholinergic?? cause vagus stimulate G cell by GRP= gastrin releasing petptide, not ACTh see FA gastroenterlogy section). 10 D spherocytosis. not pale centre in RBC+ unconjugated bilirubin 11 B (vinblastin+ vincristine + paclitaxel work on microtubules first two decreasepolymerisation , taxols does not let microtubules break down so the cell is fixed in metaphase I think :) ) 12 B 13 B (avoid eye contact = kind of autist but normal inteligence, asperger is kind of autism ) 14 F not sure( NNT = 1 / (Control Event Rate) - (Experimental Event Rate) --> 1/(0.023-0,013) 15 E 16 A 17 A 18 D (cigarette smokes in winter so i guess windows are close CO poisening) 19 A parietal cell destruction ---> intrinsic factor low ---> megaloblastic anemia. 20 A (not sure , D is wrong for sure) 21 A (klinfelter) 22 E 23 A (it"s an antagonist of acethylcholine uses in asthma) 24 E 25 A leuprilide continous stimulation of gonad lead to decrease secretion of sexe hormone (androgene is our cible in this case) 26 C 27 E (first see PH, is decreased means acidosis, she is hyperventilation means respiration started the compensatory process, after 2 days I think, the kidney will start also puting HCO3 in the blood and sectreting with the urine H+ .. NH4CL is a titrable acide means like a boat to put H+ in to send out of the body) 28 mystery question for me I could not even know the diagnosis (A is wrong) may be C just because intestine are involved :), no rational reason , please hepl to figure out the diagnosis. 29 C 2 isoenzyme means the work on the same familly of molecules . enzyme 1 is faster (300) than enzyme 2 (30) . why ? becasue the affinity of enzyme 1 is greater than enzyme 2. mmeans you need less amount of enzyme 1 then enzyme 2 (Km) 30 C 31 A 32 F (it is about apoptosis BCL2/Akt. you can google it but I am not sure)

out of the body) 28 mystery question for me I could not even know the diagnosis (A is wrong) may be C just because intestine are involved :), no rational reason , please hepl to figure out the diagnosis. 29 C 2 isoenzyme means the work on the same familly of molecules . enzyme 1 is faster (300) than enzyme 2 (30) . why ? becasue the affinity of enzyme 1 is greater than enzyme 2. mmeans you need less amount of enzyme 1 then enzyme 2 (Km) 30 C 31 A 32 F (it is about apoptosis BCL2/Akt. you can google it but I am not sure) 33 B almost sure (external validity means can you generate the result to all patients in this study the reaaly choose a very representative population with inssurance and without, different gendre different socioeconomic status. so you ac apply the result of the study on all type of patients). 34 B (infliximab is MAB for TNF) 35 C (I think in spontaneus pneumothorax you will not hear respiration at all and why will be wheezes?) 36 E (transpantation ---> CMV= virus = T lymphocytes) 37 A 38 may be D (C is wrong) 3 years 20 words: there is a prob here. MRI is expensive to start with I think :-) 39 A 40 D angiotensine converting enzyme is synthesises in the lung (I think the buzz word here is directly mediated may be...) 41 D 42 E (it is not about humerus or shoulder:so B or E she did not fall just grabbed hand and no edema) 43 D not sure ( portal hypertention ) 44 C (nitroglycerine dilate veins ans arteriol via NO) 45 C alzheimer 46 C 47 E (no change after desmopressin ) 48 F (weekness = motor, atrophy = lower MN . left =left decussation of pyramid al tract is in the medullae) 49 D (no mitosis no necrosis+ most common GYN tumor ) 50 F (steroid liposoluble acces to the cell and the nucleous). Those are my subjectifs suggestions. I would like to disscus any disagreement with you . All the best.

Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392225 maryam2009 - 05/09/11 14:36 Thank you so much Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392238 djt - 05/09/11 15:08 1 im thinking B "want to make sure that I understand your concerns about..."

maryam2009 - 05/09/11 14:36 Thank you so much Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392238 djt - 05/09/11 15:08 1 im thinking B "want to make sure that I understand your concerns about..." 3 is E because I got it right 13 is A Asperger I think you miss typed B instead of A 20 A is correct 28 is C initiate a high fiber diet 38 is D Recommend further evaluation... Thanks Borderline ^^ Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392242 usmle_guy - 05/09/11 15:11 1 is BB for sure Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392244 usmle_guy - 05/09/11 15:12 change your nick from borderline to above borderline...coz u got so many correct...... Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392264 borderline - 05/09/11 15:31 Hi Maryam your welcome @ djt .. thanks you for correcting me . yes I meant asperger for 13 . I tape it wrong sorry. so why 28 is C what this woman has ?? ulcerative collitis ?? and why ATB ? 1 .. the probleme in this question stem that the patient first come to physician to disscus transplantation so I assume that he is interested and he wants that (may be not very very exited about but considered it.) after that he told that he is unsure and after that he told that's it is ok for receiving it from a relative. so I can not figure out the exact patient position : he wants that damn kidney or not. after that the doctor initiative will be more clear. ooooops , I think you are right and this is the issue . the patient is saying yes and no in the same time so doctor need to be certain about what this patient exactley wants before advicing something to him. and it is an open question !! I think you are right and it is B . thanx djt.... Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392266 borderline - 05/09/11 15:39

that damn kidney or not. after that the doctor initiative will be more clear. ooooops , I think you are right and this is the issue . the patient is saying yes and no in the same time so doctor need to be certain about what this patient exactley wants before advicing something to him. and it is an open question !! I think you are right and it is B . thanx djt.... Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392266 borderline - 05/09/11 15:39 usmle-guy. can you give your explaination why it is B ?? thank you .. Im borderline because of the personality not the score .... if it can reassure you i scored 221 one month before the exam. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392301 djt - 05/09/11 16:12 for 28 I was thinking bacterial colitis (salmonella) because of the IV antibiotic treatment but it could also be UC because of the LLQ pain. But whether it be bacterial or autoimmune Colitis, Colitis responds well to high fiber diet and it's always advised to patients suffering from colitis. When are you sitting down for the exam?I'm sure you will slay it. ^^ @USMLE-guy I bet you will do great too ^^ Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392303 usmle_guy - 05/09/11 16:15 sorry i dont know the precise reason...somebody got correct putting that answer online..I am confused too.......... Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392306 the_kingxp - 05/09/11 16:17 hi borderline thanks for posting the answers please can u send me nbme 12 ,my exam in few days my email is zozolight2003@yahoo.com Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392309 borderline - 05/09/11 16:21 @ djt. So you reassure me because , you too do not know the diagnosis :).. I thouht that I was missing something in the stem question. I already pass the Step1 10 days ago .. still waiting . I get 231 one day before the exam. so I do not think I will have more than that . but I am glad with it . now I need SP for step 2 . are you ready ??

* Re:NMBE form 12 Section 1 . answers. #2392309 borderline - 05/09/11 16:21 @ djt. So you reassure me because , you too do not know the diagnosis :).. I thouht that I was missing something in the stem question. I already pass the Step1 10 days ago .. still waiting . I get 231 one day before the exam. so I do not think I will have more than that . but I am glad with it . now I need SP for step 2 . are you ready ?? :0) Report Abuse Guys . Im sorry I checked my wrong answers and 48 is wrong it is not F .. and i do not know what is the right answer. Im sorry . Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392340 the_kingxp - 05/09/11 17:32 Q 3 it is C for sure Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392347 borderline - 05/09/11 17:46 Hi kingxp. can you explain please. there is a rule dealing with smoking issue ? did you get it write online? thanx^^ Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392353 the_kingxp - 05/09/11 18:05 Q 16 is B for sure Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392354 the_kingxp - 05/09/11 18:06 Hi borderline the same question can be found in BRS behavior Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392360 borderline - 05/09/11 18:13 Yes Q 16 is B . i tape it wrong again , the woman is loosing blood it is abviously have nothing to do with alveolar PO2. it is blood carring capacity (the same as anemia mecanism)

Hi borderline the same question can be found in BRS behavior Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392360 borderline - 05/09/11 18:13 Yes Q 16 is B . i tape it wrong again , the woman is loosing blood it is abviously have nothing to do with alveolar PO2. it is blood carring capacity (the same as anemia mecanism) the amount of blood is decresed ---> amount of O2 carried in this blood decreases. Po2 and at stays normal. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392366 the_kingxp - 05/09/11 18:22 Q 22 I'm not sure but A seems more accurate Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392374 the_kingxp - 05/09/11 18:31 Q 28 C for sure diverticulitis Report Abuse * Re:NMBE form 12 Section 1 . answers. #2392401 borderline - 05/09/11 19:01 For the question 22 I understund your logic. you think that the loose of weight is the reason of hormonal disbalance (like in anorexia). well I was thinking that too when answering the questions but finally I choose ovarian failure because I considered that loosing 7 kg in one year periode is not enough to initiate amenorrea, and I get it right. for the question 28 Yeh I agree with C But I am not sure about the diagnosis, diverticulitis fits actually , but colitis too, anyway as I told its fiber because intestine is involved :) it is a pleasure to disscus with you ^^ @borderline- congratulations ^^ and yet you are still here helping us. You will also ace step 2 for sure. ^^ I'm far from ready. My NMBE scores are horrible and I have so little time left. Need to review FA and take one (NBME) more. ^^ Thanks for your help. ^^ Report Abuse * Re:NMBE form 12 Section 1 . answers. #2394070 barbie13 - 05/12/11 15:44 Hi can anyone send me form 7 and 12 questions with keys on pinksam13@gmail.com... thanks Report Abuse

(NBME) more. ^^ Thanks for your help. ^^ Report Abuse * Re:NMBE form 12 Section 1 . answers. #2394070 barbie13 - 05/12/11 15:44 Hi can anyone send me form 7 and 12 questions with keys on pinksam13@gmail.com... thanks Report Abuse * Re:NMBE form 12 Section 1 . answers. #2394163 step1an - 05/12/11 18:05 1. B....... not sure 3. E 20. A 28. C ....diverticulitis 29.Can u reconfirm ur answer coz i got that right but i cant recall what i put there.... :( Not sure. i think i chose B. 43. D 48. F is certainly wrong. Coz i got that wrong. Answer should be G. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2394267 sarraaaljalily - 05/12/11 22:05 i need nbme 12 q &a please Report Abuse * Re:NMBE form 12 Section 1 . answers. #2394286 borderline - 05/12/11 22:39 @step1 an 29 is C for sure. Km of the first enzyme is less them Km in the second enzyme (by 10 time) it is maths. you have a 100 good worker who can build 300 home in one year. you have onother 100 bad worker who can build just 30 home in one year. the affinity of good workers is higer than bad workers (they love theire job that's why the do it faster ) But you need just 10 good workers to do exactlety the same job as thos 100 bad workers this is your Km (it is less bay 10 in good workers that in bad workers ). 48 F is false: it is lateral horn: lettre G we should recognise that it is a cervical section http://download.videohelp.com/vitualis/med/spinal_cord_2.htm Report Abuse * Re:NMBE form 12 Section 1 . answers. #2396998 pankaj2011 - 05/18/11 01:15

48 F is false: it is lateral horn: lettre G we should recognise that it is a cervical section http://download.videohelp.com/vitualis/med/spinal_cord_2.htm Report Abuse * Re:NMBE form 12 Section 1 . answers. #2396998 pankaj2011 - 05/18/11 01:15 #14 is H...you take risk of NTD of folic acid and subtract it with trace elements. This will give you -.29/100 which you can just say is .29/100 to simplify. Therefore your ARR = .29/100 (b/c its a percentage). Then you do NNT = 1/ARR which is 344. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2397004 pankaj2011 - 05/18/11 01:37 11 isn't B. I put that answer down but it was wrong. I know that Paclitaxel stabalizes the microtubules so F cannot be answer either. Looks like its either A or E Report Abuse * Re:NMBE form 12 Section 1 . answers. #2397009 spaceman83 - 05/18/11 02:21 thank you for posting this...i was just looking for the answers to these Report Abuse * Re:NMBE form 12 Section 1 . answers. #2409458 sara84 - 06/08/11 12:08 28 C =its diverticulutis....for sure...not any colitis etc Report Abuse * Re:NMBE form 12 Section 1 . answers. #2410664 calhad - 06/10/11 18:23 14 F = They are asking any congenital anomaly, not just NTD, so it's: Attributable risk= 2,3%-1,0% = 1% NNT = 1/1% = 100 Hey guys! 29 is not C. I just took the online version and it was my choice and its wrong. argh. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2411098 jdoc208 - 06/11/11 20:06 1. BAEDF 6. EBBCD 11. BBAFE 16. BADAA 21. AAAEA

Report Abuse * Re:NMBE form 12 Section 1 . answers. #2411098 jdoc208 - 06/11/11 20:06 1. BAEDF 6. EBBCD 11. BBAFE 16. BADAA 21. AAAEA 26. CECAC 31. AFBBC 36. EADAD 41. DEDCC 46. CEGDF Report Abuse * Re:NMBE form 12 Section 1 . answers. #2411139 jkuo - 06/11/11 21:32 hey guys 22 is D) Mucocutaneous Lymph node syndrome (Kawasaki disease) Report Abuse * Re:NMBE form 12 Section 1 . answers. #2411534 tjohnson - 06/12/11 20:27 @jkuo hey, why do you think it's ML node syndrome due to Kawasaki? Isn't kawasaki more of a children's disease with other manifestations? This patient is 26yo. Could you let me know me know...i tried looking for it online but couldn't find anything. =/ thank you! Report Abuse * Re:NMBE form 12 Section 1 . answers. #2415657 sgamer1770 - 06/19/11 11:14 Why can't 26 be a, fas ligand recognizes cells with MHC 1 and helps destroy it. MHC I is just there presenting it. It doesn't recognize, it just presents. A technicality but the NBME is like that. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2415660 sgamer1770 - 06/19/11 11:17 q26 a 6-month-boy is diagnosed with respiratory syncytial virus infection. Which of the following cell surface protein complexes is most likely involved in recognition and clearance of virus-infected cells in this patient? a fas ligand b interleukin-2 (IL-2) receptor c MHC I d TNF receptor

#2415660 sgamer1770 - 06/19/11 11:17 q26 a 6-month-boy is diagnosed with respiratory syncytial virus infection. Which of the following cell surface protein complexes is most likely involved in recognition and clearance of virus-infected cells in this patient? a fas ligand b interleukin-2 (IL-2) receptor c MHC I d TNF receptor Report Abuse * Re:NMBE form 12 Section 1 . answers. #2415663 sgamer1770 - 06/19/11 11:26 for q 29 An experiment is designed to study the differences between two tissuespecific isozymes of a particular enzyme. The Vmax, of enzyme 1 is 300 units of activity per minute per milligram of protein, whereas the Vmax of enzyme 2 is 30 units of activity per minute per milligram of protein. Based on these numbers, which of the following conclusions about the K,. values for enzyme 1 and enzyme 2 is most accurate? A) The Km. cannot be predicted based solely on the value of Vmax. B) The Km for enzyme 1 and the Km for enzyme 2 will differ but cannot be quantified with the given data. C) The Kmax for enzyme 1 is one-tenth the Km enzyme 2 D) The Kmax for enzyme 1 is ten times greater than the Km for enzyme 2 E) They are the same I think they want us to realize that Km and Vmax are independent of each other. That is why so many problems we get involve determining the effect of competitive and noncompetitive inhibitors. They affect an enzyme differently without effecting the other variable. Any thoughts. Report Abuse * Vinblastine #2415948 toastedbiscuits - 06/19/11 23:01 From an old article The vinblastine binding activity of tubulin decayed upon aging, but this property was not studied in detail. Vinblastine did not depolymerize stable sea urchin sperm tail outer doublet microtubules, nor did it bind to these microtubules. However, tubulin solubilized from the B subfiber of the outer doublet microtubules possessed the two high affinity binding sites (KA = 1-3 X 105 l./mol). These data suggest that vinblastine destroys microtubules in cells primarily by inhibition of microtubule polymerization, and does not directly destroy preformed microtubules. In other words, it stops dynamic assembly and disassembly (from G-actin to F-actin) so 11 is A Report Abuse * Re:NMBE form 12 Section 1 . answers. #2415949

X 105 l./mol). These data suggest that vinblastine destroys microtubules in cells primarily by inhibition of microtubule polymerization, and does not directly destroy preformed microtubules. In other words, it stops dynamic assembly and disassembly (from G-actin to F-actin) so 11 is A Report Abuse * Re:NMBE form 12 Section 1 . answers. #2415949 toastedbiscuits - 06/19/11 23:08 I think 16 is B Alveolar Po2 is going to be the same as she is doesn't have any respiration problems. the heartburn means she's probably losing blood and this is the reason for the anemia lost of hg doesn't have a direct affect on most PO2 measurements as they only account for 3% of the total O2 - like it's easy to decant and fill a shot glass it's the fact that she has less carrying capacity - where most of her O2 is store. Like your teapot has shrunken to the size coffee mug instead of the normal size of a med study coffee pot. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2415953 toastedbiscuits - 06/19/11 23:19 26 I'm going with A Fas Ligand It's the thing that induces apoptosis whereas MHC is a negative regulator- If cd8/NK sees MHC I it will recognize it as a friendly and let the cell go [inhibitory signal]. also nk action is not restricted to MHC I cells so it has to have another mechanism to recognize bad cells so since the question asks about clearance - i went with fas Report Abuse q 40 is renin, E? The woman's hypertension is directly mediated by a vasoconstrictor that emerges from what so this means what secretes it? right renal vein renin activity is 176 - super duper high. that renin comes from the jga right? good grief - exam is tomorrow, i should not be having these questions - but spend the day napping and going to an awesome korean restaurant :)

The woman's hypertension is directly mediated by a vasoconstrictor that emerges from what so this means what secretes it? right renal vein renin activity is 176 - super duper high. that renin comes from the jga right? good grief - exam is tomorrow, i should not be having these questions - but spend the day napping and going to an awesome korean restaurant :) Report Abuse * Re:NMBE form 12 Section 1 . answers. #2415960 toastedbiscuits - 06/19/11 23:33 42 E is called nursemaid's elbow :) Report Abuse * Re:NMBE form 12 Section 1 . answers. #2416615 sgamer1770 - 06/21/11 08:33 I took the test, it marked MHC I as correct. It also marked the original vinblastine answer correct. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2416944 sgamer1770 - 06/21/11 20:31 no 40 is d, pulmonary vasculature has ACE enzyme that makes AGII Report Abuse * Re:NMBE form 12 Section 1 . answers. #2419619 maryam2009 - 06/26/11 00:53 ** Report Abuse * Re:NMBE form 12 Section 1 . answers. #2421396 jeezubal - 06/29/11 13:28 11 B is correct actin is used in making microfilaments. tubulin is polymerized to microtubles. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2421543 reeya - 06/29/11 17:51 can any one send me offline nbme or tell me frm where i can down load it.my id is meerup12@yahoo.com Report Abuse * Re:NMBE form 12 Section 1 . answers. #2431874

* Re:NMBE form 12 Section 1 . answers. #2421543 reeya - 06/29/11 17:51 can any one send me offline nbme or tell me frm where i can down load it.my id is meerup12@yahoo.com Report Abuse * Re:NMBE form 12 Section 1 . answers. #2431874 overcomer11 - 07/16/11 22:06 16 is B. In anemia there is normal PO2 and normal O2 saturation but reduced arterial O2 carrying capacity. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2434238 liaison4fun - 07/20/11 14:37 @ borderline 22 answer is a coz sleep disturbances compounded wid decreased food intake and depression may cause gnrh pulse release pattern to change and if this pulses etc change..it suppresses menstruation... Report Abuse * Re:NMBE form 12 Section 1 . answers. #2434246 helpwithstep1 - 07/20/11 14:44 @borderline, could you plz send me the nbme 12 as well .. my exam is coming up soon. thanks in advance .. shreysaad82@yahoo.com Regarding #26 --> AA Fas-ligand (FasL) is a major immune effector molecule that can contribute to the clearance of respiratory viruses. I googled it. And found an abstract to a research paper.. here's the link http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676854/ Report Abuse * Re:NMBE form 12 Section 1 . answers. #2456894 chiqui23 - 08/25/11 00:44 #29 The relationship b/w Km and Vmax is = Km = [S] @ 1/2 Vmax, so the answer Enzyme 1 => Km = [S] @ 1/2 (300) ~ 150 Enzyme 2 => Km = [S] @ 1/2 (30) ~ 15 I think should be - DD - Km for enzyme 1 is 10 times greater than enzyme 2. Report Abuse

#29 The relationship b/w Km and Vmax is = Km = [S] @ 1/2 Vmax, so the answer Enzyme 1 => Km = [S] @ 1/2 (300) ~ 150 Enzyme 2 => Km = [S] @ 1/2 (30) ~ 15 I think should be - DD - Km for enzyme 1 is 10 times greater than enzyme 2. Report Abuse * Re:NMBE form 12 Section 1 . answers. #2472175 luckysharp - 09/13/11 10:01 DEAR borderline, could you plz send me the nbme 11, 12 as well .. my exam is coming up soon. thanks in advance !!!!!!! my email adress:creek168@gmail.com Report Abuse * Re:NMBE form 12 Section 1 . answers. #2481304 montre - 09/22/11 00:28 Borderline..could you please send me NBME 12 if you have 11 either mcq. monicaszczsn@yahoo.com Thanks in advance ;) Report Abuse * Re:NMBE form 12 Section 1 . answers. #2481364 asalyase - 09/22/11 03:15 Hi, could someone plz email me NBME 12 q and ans too plz. Thanks in advance. My email is : asalyase@yahoo.com Report Abuse * Re:NMBE form 12 Section 1 . answers. #2483555 docsmily - 09/24/11 21:06 1. BAEDF 6. EBBCD 11. BBAFE 16. BADAA 21. AAAEA 26. CECAC 31. AFBBC 36. EADAD 41. DEDCC 46. CEGDF correction 2-D,3-C (got them right online)
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31. 36. 41. 46.

AFBBC EADAD DEDCC CEGDF


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correction 2-D,3-C (got them right online)

* Re:nbme 12 needed pl with explanations asap!

munira1980 - 04/10/12 22:27

#2639249

E Normal renal architecture (tubular re-epithelization after ATN) 2 B E-cadherin 3 A Bromocriptin (increase Dopamine=Prolactin inhibitor) 4 E Serum TG will decrease (increase in HPL) 5 A Blockade of leukotriene receptor 6 C 4 prevalent cases in Dec. 31 7 E UDP glucuronosyltransferase deficiency 8 E Leptin 9 C? hypertrophic cardiomyopathy leading to pulmunary stenosis? 10 C malrotation (tip Chest x-ray + abrupt onset of pain) 11? B is wrong 12 B Heart failure (classic CHF) 13 D Norepinephrine 14 B "I see some bruising..." 15 D Improved cellular responsiveness to insulin 16 D Failure of urogenital folds to fuse 17 C Nonseminoma neoplasm 18 C Lysosome(lysosomal disease) 19 E Myopathy and hepatotoxicity 20 F Renal agenesis 21? C is wrong (maybe A?) 22 A Early diastole (diastole is when coronary artery flow is maximum,I answered C and it's wrong) 23 C Hypertensive retinopathy 24 E Renal cell CA 25 C Phrenic nerve 26 E Partial agonism 27 D? Reassortment of hemagglutinin? or E? (F is wrong) 28 E Hypertrophic cardiomyopathy 29 E Rubella (THORCH) 30 B Indinavir? 31 C Mebendazole (swimmers itch caused by non-human schistosoma) 32 ? (E is wrong) 33? (B is wrong) 34 D Placement of external defibrillators...(can see fastest result) 35 D Subjects with no evidence of colonic polyposis 36 E increase in Hgb F conc. 37 B Fc receptor 38 C Oligodentdrocytes (MS) 39 C Regeneration of muscle fibers (showing fiber grouping) 40 B Absent pain proximal fibula, Present pain distal fibula, Dorsiflextion 0/5, Plantar flexion 4/5, Achilles reflex 1+

32 ? (E is wrong) 33? (B is wrong) 34 D Placement of external defibrillators...(can see fastest result) 35 D Subjects with no evidence of colonic polyposis 36 E increase in Hgb F conc. 37 B Fc receptor 38 C Oligodentdrocytes (MS) 39 C Regeneration of muscle fibers (showing fiber grouping) 40 B Absent pain proximal fibula, Present pain distal fibula, Dorsiflextion 0/5, Plantar flexion 4/5, Achilles reflex 1+ 41 A (cuneate, gracile and Trigeminal Nerve location) 42 D Type IV(delayed) 43 ? maybe A (B is wrong) 44 C Decrease in Median, Unchanged Mode, Decreased Mean 45 D Stool assay for toxin (C. deficile) 46 A Autosomal dominant with variable expressivity 47 D Vit. C 48 F wearing a helmet 49 B Chlamydia trachomatis (silver nitrate didn't prevent, intracytoplasmic inclusions) 50 C Multiple myeloma (osteolytic bone lesions and rouleaux formation Corrections and answers to my unsure ones would be appreciated ^^ Borderline please help me out with this and please post the section 3 anwers, Thanks ^^ Report Abuse * Re:NBME form 12 section 2 answers #2392716 usmle_guy - 05/10/11 12:23 are you sure 4 is E??? 9 should be F..normal physiological.. 11..C...gain of function 27..reassortment of hemaglutining 30 B..I think Indinavir too.not sure 32 E urolithiasis( 100% sure) 33 A budding..for sure 34 ..are u sure????? is it DDD..i think A is correct 40 is CCC 43 Is CC formation of disulfide Report Abuse * Re:NBME form 12 section 2 answers #2392734 djt - 05/10/11 13:31 thanks usmle_guy.^^ 4 E I think that's what I answered and got right.( not 100 sure though) Do you have another suggestion? 9 Oh the patient is pregnant...so stupid of me to miss that ^^ F is correct ^^ 32 I answered D urolithiasis but it is marked wrong... 34 yes I'm sure. antismoking campaign would take too long to see

* Re:NBME form 12 section 2 answers #2392734 djt - 05/10/11 13:31 thanks usmle_guy.^^ 4 E I think that's what I answered and got right.( not 100 sure though) Do you have another suggestion? 9 Oh the patient is pregnant...so stupid of me to miss that ^^ F is correct ^^ 32 I answered D urolithiasis but it is marked wrong... 34 yes I'm sure. antismoking campaign would take too long to see results. She wanted results in 1-2 years time. 40 is C I agree with you. Don't know what I was thinking there. ^^ Thank you usmle_guy ^^ how's your prep going? did you hear questions having more weight on Microbio and Gen Principles after May 17? Report Abuse * Re:NBME form 12 section 2 answers #2392748 doc_study - 05/10/11 14:02 4. should be A. DK, metabolic acidosis leading to compensatory dec. in pCo2. 11. C 21. A 27. D 30. B 32. A 33. A 34. D 43. D Report Abuse * Re:NBME form 12 section 2 answers #2392759 usmle_guy - 05/10/11 14:17 I am moving...15 days to go..approx...I have heard about Immuno thing...I can't do anything for that...If they are planning to screw us, Let them do that...,,can't do PhD in Immuno either,,,, Report Abuse * Re:NBME form 12 section 2 answers #2392762 djt - 05/10/11 14:31 usmle_guy - yeah. let's just stick to our study plan. There is no time to panic. Not now ^^ You will do great. Your NBME scores are quite solid if you ask me. I'm predicting a +10 of your NBME score on the real exam ^^ Report Abuse * Re:NBME form 12 section 2 answers #2392765 djt - 05/10/11 14:34 Thank you doc_study for you contribution ^^ GBU ^^ Do you have answers for section 3?

panic. Not now ^^ You will do great. Your NBME scores are quite solid if you ask me. I'm predicting a +10 of your NBME score on the real exam ^^ Report Abuse * Re:NBME form 12 section 2 answers #2392765 djt - 05/10/11 14:34 Thank you doc_study for you contribution ^^ GBU ^^ Do you have answers for section 3? Report Abuse * Re:NBME form 12 section 2 answers #2392769 doc_study - 05/10/11 14:45 i dont have the answers, post the questions i will try to answer. Report Abuse * Re:NBME form 12 section 2 answers #2396916 pankaj2011 - 05/17/11 22:54 Hey #39 is wrong. I also put C and it came out as wrong. Ill post the question on here: In a patient with chronic peripheral neuropathy, enzyme histochemical staining of a muscle biopsy shows fiber grouping. Which of the following is most likely cause of this finding? a) altered expression of muscle enzyme due to damaged nerve fibers b) altered trophic substance from the innervating neurons c) regeneration of muscle fibers (WRONG ANSWER) d) reinnervation of muscle fibers by regenerating axons e) selective loss of nerve fibers to type II muscle fibers Report Abuse * Re:NBME form 12 section 2 answers #2396928 pankaj2011 - 05/17/11 23:10 Also can somebody please explain #10 for me? Its the one with the 2 abdominal x-rays and according to the orginal poster its C. I have no clue what that is. Thank you! Report Abuse * Re:NBME form 12 section 2 answers #2398282 marc923 - 05/19/11 19:03 10 is C , not B Hey #39 is wrong. I also put C and it came out as wrong. Ill post the question on here: In a patient with chronic peripheral neuropathy, enzyme histochemical staining of a muscle biopsy shows fiber grouping. Which of the following is most likely cause of this finding? a) altered expression of muscle enzyme due to damaged nerve fibers b) altered trophic substance from the innervating neurons

10 is C , not B Hey #39 is wrong. I also put C and it came out as wrong. Ill post the question on here: In a patient with chronic peripheral neuropathy, enzyme histochemical staining of a muscle biopsy shows fiber grouping. Which of the following is most likely cause of this finding? a) altered expression of muscle enzyme due to damaged nerve fibers b) altered trophic substance from the innervating neurons c) regeneration of muscle fibers (WRONG ANSWER) d) reinnervation of muscle fibers by regenerating axons e) selective loss of nerve fibers to type II muscle fibers Report Abuse * Re:NBME form 12 section 2 answers #2401418 coquette_xlr - 05/24/11 19:48 Re:NBME12,number 39, please any one know the answe #2398633 yeabiruh - 05/20/11 05:10 Hi there .... Chronic peripheral neuropathies bring myopatholgical changes in respective muscle groups that lost or regain innervation (secondary to the chronic peripheral neuropathies )...... -The most common changes in dennervation are atrophic fibres and fibre groups.... Reinnervation takes place in the chronic neuropathies......type grouping is a feature of reinnervation .... -Hence histopatholgical changes of chronic peripheral neuropathies include both of the ABOVE.... -What is type grouping....remember muscle has type I and II fibers (A 5 dollar word for cell)...normally type I and Type II arrange like Checkerboard" pattern of type I (Light) and II (Dark) fibers....but in type grouping Type I and type II muscle fibers are clustered in large groups (Type I together and Type II together )... -Type grouping signifies clustering of muscle fibres of the same metabolic type, and is a frequent finding in reinnervated muscles..... -Reinnervation occurs spontaneously in most cases. Usually this happens by having a nearby nerve grow a new axon that will gradually take over the deinnervated tissue....

hence choice D is the most likely answer.... the key word is knowing what TYPE GROUPING IS ....And know reinnervation causes it... Report Abuse * Re:NBME form 12 section 2 answers #2401430 coquette_xlr - 05/24/11 20:19

the deinnervated tissue....

hence choice D is the most likely answer.... the key word is knowing what TYPE GROUPING IS ....And know reinnervation causes it... Report Abuse * Re:NBME form 12 section 2 answers #2401430 coquette_xlr - 05/24/11 20:19 What is the Dx in Q 41? im so lost in that one!!! help Report Abuse * Re:NBME form 12 section 2 answers #2408246 jdoc208 - 06/06/11 13:37 for 38, you meant "38 D Oligodentdrocytes (MS)" not C Report Abuse * Re:NBME form 12 section 2 answers #2409553 sara84 - 06/08/11 14:15 31 is ancylostoma ( cutaneous larva migrans) Report Abuse * Re:NBME form 12 section 2 answers #2409571 sara84 - 06/08/11 14:56 Q 35 TALKS ABT CASES AND CONTROL.... they are studying association b/w familial polyposis and colorectal cancer I think answer should be C (NOT D) 'coz FAMILIAL POLYPOSIS IS THE RISK FACTOR AND we dont include risk factor in controls...infact we are trying to find an association of disease with risk factor in case control study.... Comparing exposure status in cases and control confounds the analysis. Report Abuse * Re:NBME form 12 section 2 answers #2409573 sara84 - 06/08/11 15:00 Q 39 IN patients suffering from diseases of the lower motor neurone, grouping of muscle fibres of histochemical type 1 associated with a raised functional terminal innervation ratio has been demonstrated. This could be explained in either of two ways: (1) the neurones innervating type 2 muscle fibres are more susceptible to degeneration and when this occurs the denervated muscle fibres are re-innervated by collateral sprouts from nerve fibres previously innervating type 1 fibres. The type 2 fibres then take on the histochemical properties of type 1 fibres, which is in accordance with the demonstration24 that when a nerve previously serving a muscle containing predominantly type 1 fibres is transplanted into a muscle containing predominantly type 2 fibres, the histochemical characteristics of the latter become those of type 1 fibres. The

grouping of muscle fibres of histochemical type 1 associated with a raised functional terminal innervation ratio has been demonstrated. This could be explained in either of two ways: (1) the neurones innervating type 2 muscle fibres are more susceptible to degeneration and when this occurs the denervated muscle fibres are re-innervated by collateral sprouts from nerve fibres previously innervating type 1 fibres. The type 2 fibres then take on the histochemical properties of type 1 fibres, which is in accordance with the demonstration24 that when a nerve previously serving a muscle containing predominantly type 1 fibres is transplanted into a muscle containing predominantly type 2 fibres, the histochemical characteristics of the latter become those of type 1 fibres. The mechanism by which this change comes about is uncertain, but it may be dependent on the frequency of passage of impulses along the nerve fibres5, a higher frequency favouring development of type 2 characteristics. The evidence against this explanation lies in the absence in most of our cases with type 1 grouping of any atrophic type 2 fibres. It is possible, however, that all the denervated fibres became re-innervated before they had time to atrophy. Further, where atrophic muscle fibres are present in primary disease of the lower motor neurone, in our experience (with human muscle) they are rarely predominantly type 2. (2) The re-innervating terminal sprouts, whether from axons of neurones previously serving muscle fibres of type 1 or 2, may be insufficiently mature to enable them to conduct every impulse reaching them from the parent axon. Thus the frequency of stimulation of the re-innervated muscle fibres would be substantially reduced. In these circumstances the type 2 muscle fibres, whether re-innervated by sprouts from axons previously serving type 1 or 2 fibres, would assume type 1 characteristics. Original type 1 fibres re-innervated in this way would, of course, retain their original histochemical characteristics irrespective of the type of muscle fibre previouslyand stillinnervated by the parent axon of the re-innervating sprou Report Abuse * Re:NBME form 12 section 2 answers #2409577 sara84 - 06/08/11 15:06 39 D Report Abuse * Re:NBME form 12 section 2 answers #2409708 jdoc208 - 06/08/11 19:22 just an fyi to everyone, here are my answers: 1. EBAAA 6. CEEFC 11. CBDBD 16. DCCEF 21. AACEC 26. EDEEB 31. CAADD 36. EBCDC 41. ADDCD 46. ADFBC Report Abuse * Re:NBME form 12 section 2 answers #2411068 jdoc208 - 06/11/11 18:56

21. AACEC 26. EDEEB 31. CAADD 36. EBCDC 41. ADDCD 46. ADFBC Report Abuse * Re:NBME form 12 section 2 answers #2411068 jdoc208 - 06/11/11 18:56 1. EBAAA 6. CEEFC 11. CBDBD 16. DCCEF 21. AACEC 26. EDEEB 31. CAADD 36. EBDDC 41. ADDCD 46. ADFBC Hey jdoc....are u sure 35 is D...???? Report Abuse * Re:NBME form 12 section 2 answers #2411100 jdoc208 - 06/11/11 20:09 pretty sure it's D Report Abuse * Re:NBME form 12 section 2 answers #2412322 sr21722 - 06/14/11 09:53 Does anyone have nbme12 section 4 answers, the links that are posted online have been blocked... please send to usmle300@gmail.com Thank you!! Report Abuse * Re:NBME form 12 section 2 answers #2412679 reddy704 - 06/14/11 20:34 43 c I got it right Report Abuse * Re:NBME form 12 section 2 answers #2415679 sgamer1770 - 06/19/11 12:07 How come 21 is not c? URI leading spreading to bronchitis? Report Abuse * Re:NBME form 12 section 2 answers #2415680 sgamer1770 - 06/19/11 12:11

* Re:NBME form 12 section 2 answers #2415679 sgamer1770 - 06/19/11 12:07 How come 21 is not c? URI leading spreading to bronchitis? Report Abuse * Re:NBME form 12 section 2 answers #2415680 sgamer1770 - 06/19/11 12:11 21 is a. from medscape http://www.medscape.com/viewarticle/717071 Respiratory infections are associated with wheezing illnesses at all ages and may also impact the development and severity of asthma. Respiratory tract infections caused by viruses,[13] Chlamydophila [47] or Mycoplasma [5,810] have been hypothesized to have significant roles in the pathogenesis of asthma. Of these respiratory pathogens, viruses have been shown to be epidemiologically associated with asthma in several ways. First, particular viruses associated with infantile wheezing have been theorized to lead to the inception of the asthmatic phenotype. [11,12] Second, children who experience severe viral respiratory infections in early life are more likely to have asthma later in childhood. [3,11,13] Furthermore, in children and adults with established asthma, viral upper respiratory tract infections (URIs) play a key role in producing acute exacerbations that may lead to healthcare utilization.[1416] Several host factors, such as allergic sensitization[14,17] and virusinduced interferon responses,[1820] modify the risk of virus-induced wheezing. For infections with other microbes, interest has focused on Chlamydophila and Mycoplasma as possible contributors to both acute exacerbations and the severity of chronic asthma.[5,7] Finally, colonization of the upper airways in infancy with common bacterial pathogens has been demonstrated to increase the risk of subsequent asthma.[21] We review these various associations as they pertain to the development and exacerbation of asthma. Report Abuse * Re:NBME form 12 section 2 answers #2415695 sgamer1770 - 06/19/11 12:40 for 40? A 35-year-old woman is brought to the emergency department after she sustains a fracture of the neck of the fibula of her right leg. She was struck by a car while crossing the street. Which of the following findings is most likely on examination of the affected leg? Pain Over ---------Pain Over Proximal Fibula -Distal Fibula- Dorsiflexion- Plantar Flexion -Achilles Reflex A Absent ------------absent 4/5 1/5 1+ B Absent ------------present 015 4/5 1 + C Present ------------absent 1/5 4/5 2+ D Present -----------absent 5/5 0/5 absent E Present ------------present 4/5 4/5 2+ Report Abuse * Re:NBME form 12 section 2 answers #2415697

C Present ------------absent 1/5 4/5 2+ D Present -----------absent 5/5 0/5 absent E Present ------------present 4/5 4/5 2+ Report Abuse * Re:NBME form 12 section 2 answers #2415697 sgamer1770 - 06/19/11 12:41 i also think it is c, absent pain distally because the nerve has been cut, any comments? Report Abuse * Re:NBME form 12 section 2 answers #2419618 maryam2009 - 06/26/11 00:52 ** Report Abuse * Re:NBME form 12 section 2 answers #2483563 mat9775 - 09/24/11 21:39 9- S3 is increase in pregnant women is normal response not S2 43 D Read the question carefully. It is not alanine that is replaced by serine, but rather serine has been replaced by alanine. Serine having a hydroxyl group (like threonine and tyrosine) is one of the commonly phosphorylated residues (remember serine/threonine kinases and tyrosine kinase?) or O-glycosylated residues.

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* Re:nbme 12 needed pl with explanations asap!

munira1980 - 04/10/12 22:28

#2639250

NBME 12 section 3 answers. #585674 borderline - 05/13/11 01:26 1E 2 C (almost sure) any other suggestions ? 3A 4E http://cid.oxfordjournals.org/content/31/2/578.short another hint (chlamydophila = Legionella pneumophila, Mycoplasma pneumoniae and Chlamydophila pneumoniae) are intracellular bugs--> need t lymphocyte to extermine the infection) 5E 6B

1E 2 C (almost sure) any other suggestions ? 3A 4E http://cid.oxfordjournals.org/content/31/2/578.short another hint (chlamydophila = Legionella pneumophila, Mycoplasma pneumoniae and Chlamydophila pneumoniae) are intracellular bugs--> need t lymphocyte to extermine the infection) 5E 6B 7B 8C 9D 10 C 11 B 12 A (two choises can be reasonable inner cell of the cochlea C or the A, but if she has sensorineural hearing loss, I think those cell are most commonlt in ealderly to be damged so it is useless to innervate them by the implant) 13 E 14 B 15 A 16 C (you will get those question in the exam garantee, learn how to draw 2 by 2 table and you will get all question about sensitivity , specificity, PPV , NPV , Odd ratio and RR and attribuate risk .. it is just unfair to loose those questions) 17 A (i get this question wrong i marked dependent I get so upset that i choose bordeline as my pseudo to never forget) 18 C how does not know the blue magical pill....;) 19 C 20 D 21 D 22 E 23 E 24 D 25 B 26 C 27 C (mneumonic Musculocutaneous= muscle= show me your biceps..:-)) 28 E (it is gout but can someone tell me why this story happend after the cholecystectomy ??) 29 F (almost sure any suggestions ) 30 B b-thalassemia is an imcoplete globine chain that work inappropraitely. if you chage G by A at position 246 , the RNA will have an stop codon dna ATT--> RNA UAA (U are away = stop codon thanx FA for mneumonic) 31 B (can someone please explain the concept of having hypersplenisme in alcoholics ?? because of portal hypertention ?) 32 A 33 D 34 D 35 C 36 C 37 D (I think he has MI complicated by cardiogenic choc left heart failure so the Pul oedema, Do you have another suggestion what the diagnosis might be ?) 38 D 39 B 40 A 41 A 42 C

34 D 35 C 36 C 37 D (I think he has MI complicated by cardiogenic choc left heart failure so the Pul oedema, Do you have another suggestion what the diagnosis might be ?) 38 D 39 B 40 A 41 A 42 C 43 A 44 B 45 B 46 A 47 A 48 D 49 D 50 A Again that are my suggestions. If you have another choise please let me know and we will discuss that so we all will learn from our mistakes . Thank you .

Report Abuse * Re:NBME 12 section 3 answers. #2394441 maryam2009 - 05/13/11 08:30 Hi Borderline I appriciate your effort and kindness , :) Report Abuse * Re:NBME 12 section 3 answers. #2396974 pankaj2011 - 05/18/11 00:19 Hey borderline, Could you explain why #9 is D (mitochondria); I am kinda lost with that question. For number 28, the reason the answer is gout after occuring postcholycysectomy is b/c people have to usually restrict their fluid intake before a surgery and that will lead to a concentrated uric acid level in the blood (esp since he has the 2 year history of gout). Remember that large meals and alcohol consumption can precipitate gout attacks as well. Thanks for posting the answers. Report Abuse * Re:NBME 12 section 3 answers. #2397814 sssdewi - 05/19/11 01:41 @ Borderline,

blood (esp since he has the 2 year history of gout). Remember that large meals and alcohol consumption can precipitate gout attacks as well. Thanks for posting the answers. Report Abuse * Re:NBME 12 section 3 answers. #2397814 sssdewi - 05/19/11 01:41 @ Borderline, Thanks for posting answers. Please help me explain for No. 26 (why choose opioid....)??? And also for No. 30. (I can't find any clue to get answer in No. 30). Report Abuse * Re:NBME 12 section 3 answers. #2397858 sssdewi - 05/19/11 06:10 Question No. 42 I think is A (Congenital hypothyroidism). Thymus aplasia + hypothyroidism in Digeorge syndrome. Why the answer is C???? Explanation please.... Report Abuse * Re:NBME 12 section 3 answers. #2398588 borderline - 05/20/11 01:43 For the question 9 ; goljan said in RR that aspirin is a mitochondrial (uncoupling) poison there is even a schema where he shows where it acting . Seizure I think it is because of ATP depletion (I think the same mecanisme of melas syndrome http://emedicine.medscape.com/article/946864-overview) thanx for the explanation of 28 pankaj Report Abuse * Re:NBME 12 section 3 answers. #2398594 borderline - 05/20/11 01:59 @ sssdewi for 26 : nothing other feets actually ARS and pneumenia (lung are clear to auscultation) respiration rate is very low (8), why you will have this in pulmonary embolism, you will have a shunt and hypoxia but why the respiration rate will decresed if any thing I guess it will increased because of the hypoxia (not sure) upper airway obstruction you will hear minimal or no respoiration sure but it will be different hearing between the right and the left lung cause of this obstuction. generally MS patients had congnitif decline and depression so.. I thing suicide attemps feets better .

nothing other feets actually ARS and pneumenia (lung are clear to auscultation) respiration rate is very low (8), why you will have this in pulmonary embolism, you will have a shunt and hypoxia but why the respiration rate will decresed if any thing I guess it will increased because of the hypoxia (not sure) upper airway obstruction you will hear minimal or no respoiration sure but it will be different hearing between the right and the left lung cause of this obstuction. generally MS patients had congnitif decline and depression so.. I thing suicide attemps feets better . for 30 do the change then transcript this DNA to mRNA and you will find out a stop codon (in thalassemia that what makes the globin not functional its translation is not completed) for 42 youre right it is di georgi and it is A. I just makes a mistake when tapping ... sorry . Report Abuse * Re:NBME 12 section 3 answers. correction 43 D #2399524 monoo18 - 05/21/11 13:57 Hi I normally just lurk and dont have much to add cuz im not that good of a student, but i saw that answer 42 in the list is not correct....... i took the mock yesterday online and they give u the questions that u got wrong ..... I did not get #43 wrong otherwise it would have been in the 49 q's i missed .... I chose D respectively .... so it has to be the correct answer... its kinda an easy question so im certain u jus had a typo.... nothing groundbreaking on my part.. neways ive used the help from several pepl... drona maryam... borderline... in this forum.... my contribution... albeit.... microscopic in significance :) .... electron microscopic :) Report Abuse * Re:NBME 12 section 3 answers. #2399527 usmleny - 05/21/11 14:19 Borderline... thank you so much...i really appreciate your help.... Report Abuse * Re:NBME 12 section 3 answers. #2399538 borderline - 05/21/11 14:37 @monoo18 you`re right the 42 question is wrong if you read the disscucion after the post I mentioned that it was di-gorgi and i make a fault typing , so I m very sorry for that .. your microscopical contribution is like diagnostic test in minimal change disease . a gold standart.... :) Report Abuse * Re:NBME 12 section 3 answers. #2399540 borderline - 05/21/11 14:38 your welcome guys...

@monoo18 you`re right the 42 question is wrong if you read the disscucion after the post I mentioned that it was di-gorgi and i make a fault typing , so I m very sorry for that .. your microscopical contribution is like diagnostic test in minimal change disease . a gold standart.... :) Report Abuse * Re:NBME 12 section 3 answers. #2399540 borderline - 05/21/11 14:38 your welcome guys... 43 should be D can somebody clarify plzz Report Abuse * Re:NBME 12 section 3 answers. #2405039 maroon - 05/31/11 12:28 Greetings borderline. Is this NBME 12 Block 3 questions and answers because they do not correspond. Did you take the standard or extended time period during examination of the NBME Form 12 Block 3. I am somehat confused since your answers do not correspond with the questions. Could you email the questions plus answers to brainwl2000@yahoo.com Report Abuse * Re:NBME 12 section 3 answers. #2409643 sara84 - 06/08/11 17:01 2E In developed countries, the most common causes of chronic pancreatitis are gallstones (est. 40%), alcohol (est. 30%) and idiopathic (of unknown cause - the remaining 30%). Report Abuse * Re:NBME 12 section 3 answers. #2409650 sara84 - 06/08/11 17:15 In individuals with sensorineural hearing loss, hair cells are often fewer in number and damaged. Hair cell loss or absence may be caused by a genetic mutation or an illness such as meningitis. Hair cells may also be destroyed chemically by an ototoxic medication, or simply damaged over time by excessively loud noises. The cochlear implant bypasses the hair cells and stimulates the cochlear nerves directly using electrical impulses. This allows the brain to interpret the frequency of sound as it would if the hair cells of the basilar membrane were functioning properly 12B B Report Abuse * Re:NBME 12 section 3 answers. #2409653 ethanfrome - 06/08/11 17:28 9. is Reye's syndrome. Report Abuse

hair cells of the basilar membrane were functioning properly 12B B Report Abuse * Re:NBME 12 section 3 answers. #2409653 ethanfrome - 06/08/11 17:28 9. is Reye's syndrome. Report Abuse * Re:NBME 12 section 3 answers. #2409661 sara84 - 06/08/11 17:43 Kleine-Levin_syndrome 22B People with KLS are often mistakenly diagnosed with a psychiatric disorder. The periods of somnolence, hyperphagia, and withdrawal can mimic severe depression, and some people experience a brief period of high energy following these episodes which looks like a manic episode, so that some patients are incorrectly diagnosed with bipolar disorder. There can also be a number of other mood symptoms or perceptual disturbances which mimic primary psychiatric disorders. Narcolepsy and Klver-Bucy syndrome can also produce similar symptom profiles. Before a final diagnosis can be made, all other possibilities must be carefully excluded, and the cluster of symptoms must fit with those commonly observed in KLS patients.[15] Report Abuse * Re:NBME 12 section 3 answers. #2409673 sara84 - 06/08/11 18:03 30 D TAA IS STOP CODON Report Abuse * Re:NBME 12 section 3 answers. #2409677 sara84 - 06/08/11 18:09 30 B*** RIGHT ANSWER Report Abuse * Re:NBME 12 section 3 answers. #2409683 sara84 - 06/08/11 18:23 42 A DIGEORGE Report Abuse * Re:NBME 12 section 3 answers. #2409686 sara84 - 06/08/11 18:29 43 D...........MI LEADING TO PAPILLARY MUSCLE RUPTURE AND MR sara84 - 06/08/11 18:31

sara84 - 06/08/11 18:23 42 A DIGEORGE Report Abuse * Re:NBME 12 section 3 answers. #2409686 sara84 - 06/08/11 18:29 43 D...........MI LEADING TO PAPILLARY MUSCLE RUPTURE AND MR sara84 - 06/08/11 18:31 Ischemic mitral regurgitation (MR) is a complication of coronary heart disease; it primarily occurs in patients with a prior myocardial infarction (MI) but also may be seen with acute ischemia, a setting in which the MR typically resolves after the ischemia resolves. In the setting of an MI, the MR is usually due to infarction with permanent damage to the papillary muscle or adjacent myocardium; in such patients, MR may become more severe with or without superimposed ischemia. Report Abuse * Re:NBME 12 section 3 answers. #2409689 sara84 - 06/08/11 18:39 I THINK 50 IS C... N LINKED GLYCOSYLATION OCCURS IN RER WHY IS A & B OUTSIDE CELL??? Report Abuse * Re:NBME 12 section 3 answers. #2409709 jdoc208 - 06/08/11 19:25 the big circle is the mitochondria, not the cell. A and B are at the ER (in the cytoplasm). glycosylation occurs at the ER. Report Abuse * Re:NBME 12 section 3 answers. #2409710 jdoc208 - 06/08/11 19:26 also, here are my answers for the whole block: 1. ECAEE 6. BBCDC 11. BAEBA 16. CACCD 21. DEEDB 26. CCEFB 31. BADDC 36. CDDBA 41. AADBB 46. AADDA Report Abuse * Re:NBME 12 section 3 answers. #2409711 sara84 - 06/08/11 19:37

21. DEEDB 26. CCEFB 31. BADDC 36. CDDBA 41. AADBB 46. AADDA Report Abuse * Re:NBME 12 section 3 answers. #2409711 sara84 - 06/08/11 19:37 In individuals with sensorineural hearing loss, hair cells are often fewer in number and damaged. Hair cell loss or absence may be caused by a genetic mutation or an illness such as meningitis. Hair cells may also be destroyed chemically by an ototoxic medication, or simply damaged over time by excessively loud noises. The cochlear implant bypasses the hair cells and stimulates the cochlear nerves directly using electrical impulses. This allows the brain to interpret the frequency of sound as it would if the hair cells of the basilar membrane were functioning properly 12B B Report Abuse * Re:NBME 12 section 3 answers. #2409712 sara84 - 06/08/11 19:38 Kleine-Levin_syndrome 22B People with KLS are often mistakenly diagnosed with a psychiatric disorder. The periods of somnolence, hyperphagia, and withdrawal can mimic severe depression, and some people experience a brief period of high energy following these episodes which looks like a manic episode, so that some patients are incorrectly diagnosed with bipolar disorder. There can also be a number of other mood symptoms or perceptual disturbances which mimic primary psychiatric disorders. Narcolepsy and Klver-Bucy syndrome can also produce similar symptom profiles. Before a final diagnosis can be made, all other possibilities must be carefully excluded, and the cluster of symptoms must fit with those commonly observed in KLS patients. Report Abuse * Re:NBME 12 section 3 answers. #2410649 calhad - 06/10/11 17:46 I choose B in question 22 and it's wrong. Report Abuse * Re:NBME 12 section 3 answers. #2410661 calhad - 06/10/11 18:10 I choose E in question 2 and it's wrong. Report Abuse * Re:NBME 12 section 3 answers. #2411856 gem351 - 06/13/11 15:04

* Re:NBME 12 section 3 answers. #2410661 calhad - 06/10/11 18:10 I choose E in question 2 and it's wrong. Report Abuse * Re:NBME 12 section 3 answers. #2411856 gem351 - 06/13/11 15:04 how is question 21 D? I thought you increase glycolysis so increased F-2.6 BP and decrease gluconeogenesis: so decreased Pyruvate kinase and PEP carboxykinase. any help appreciated! Report Abuse * Re:NBME 12 section 3 answers. #2411872 macb555 - 06/13/11 15:25 Hello Maryam/jdoc/borderline or anyone else, Thank you very much for your great help for NBME 11 and 12. I used the "megaupload" link for the questions but I am still missing: 1) NBME 12 Block 4 Answers - I tried the link (http:// www.usmleforum.com/files/forum/2011/1/584709.php) but its not working, keeps on going to the home page 2) NBME 11 Block 1 Questions - These were not included in the zipped file. Also a quick "dumb" question - the order of the questions in the megaupload link match the answers posted above right? I would truly appreciate you sending the two things above to supersonic9@gmail.com My exam is coming up in days and I really want to prepare as well as I can. Thank you! 2-ans is c 42-ans is A 43 ans is D Report Abuse * Re:NBME 12 section 3 answers. #2415824 sgamer1770 - 06/19/11 17:58 22. A 14-year-old boy is brought to the physicians office because of decreased appetite and abdominal pain over the past 3 weeks. His mother says that during the same time he has withdrawn from everyone and sleeps constantly. He describes his symptoms vaguely. Physical examination is normal. During further history-taking, it is most critical for the physician to obtain information about which of the following? A) Developmental history B) Family history of affective disorders C) Orientation to time, place, and person D) School history E) Suicidal ideation or attempts could it be d....?? is the kid just trying to play hooky. Vague symptoms....hmmmmm Report Abuse * Re:NBME 12 section 3 answers.

A) Developmental history B) Family history of affective disorders C) Orientation to time, place, and person D) School history E) Suicidal ideation or attempts could it be d....?? is the kid just trying to play hooky. Vague symptoms....hmmmmm Report Abuse * Re:NBME 12 section 3 answers. #2415832 sgamer1770 - 06/19/11 18:19 In 28 the gout question,, what is explaining the distal heart murmur? A 55-year-old man develops fever 3 days after undergoing a cholecystectomy. He has a 2-year history of intermittent pain in his right great toe. He is 183 cm (6 ft) tall and weighs 159 kg (350 Ib); BMI 1s48 kg/rn2. His temperature is 38.3C (101 F), pulse is 1 10/mm, and blood pressure is 130170 mm Hg. Bilateral crackles and wheezing are heard on auscultation of the chest. The heart sounds are distant Abdominal examination shows a healing incision that is not inflamed. There is swelling and redness of the right first metatarsophalangeal joint. Which of the following is the most likely cause of the joint findings? A) Calcium pyrophosphate crystals B) Staphylococcus aureus infection C) Streptococcus pyogeries (group A) infection D) Synovial vasculitis E) Urate crystals Report Abuse * Re:NBME 12 section 3 answers. #2416030 toastedbiscuits - 06/20/11 03:49 quick one #18 i think is wrong note the difference between attain - vs maintain you have to have pns to attain salendafil-phosphodiesterase inhibitor to maintain :) Report Abuse * Re:NBME 12 section 3 answers. #2416364 indianjesus - 06/20/11 19:14 for number 28 this is pretty weak but i remember from our lectures that there are metabolic causes for pericarditis/pericardial effusion. "distant heart sounds" are a buzz-word for pericardial effusion, that's for sure... its just linking the two together. He was in for surgery (anesthesia or something) reduced renal clearance of uric acid resulting in pericarditis -> decreased CO -> backup of fluid into his lungs. and a gouty flare up.

this is pretty weak but i remember from our lectures that there are metabolic causes for pericarditis/pericardial effusion. "distant heart sounds" are a buzz-word for pericardial effusion, that's for sure... its just linking the two together. He was in for surgery (anesthesia or something) reduced renal clearance of uric acid resulting in pericarditis -> decreased CO -> backup of fluid into his lungs. and a gouty flare up. honestly if you look through 1st aid or Goljan you're not going to find the metabolic basis for pericarditis, it was something i learned from lecture...i checked uptodate and educus and there's a linkage between uremia and pericarditis but this may be one of those questions that I sacrifice for the greater good =) Report Abuse * Re:NBME 12 section 3 answers. #2416379 dr.taurus - 06/20/11 19:43 where can i get NBME 12 forms?i mean offline? Report Abuse * Re:NBME 12 section 3 answers. #2416975 leodudepal - 06/21/11 21:49 if 43 were rupture, then how does the murmur go away? Report Abuse * Re:NBME 12 section 3 answers. #2419617 maryam2009 - 06/26/11 00:52 ** Report Abuse * Re:NBME 12 section 3 answers. #2419693 fazl - 06/26/11 09:51 goes away b/c it ischemia and the cardiac stunning muscle functional again as ischeamia goes Report Abuse * Re:NBME 12 section 3 answers. #2419794 freestep - 06/26/11 14:07 Hi Borderline Can you please email the nbme form 11 and 12? I need them for practice. Thanks. My email kchall78@yahoo.com hi maryam, can u please explain q # 21... how ? Report Abuse * Re:NBME 12 section 3 answers.

#2419794 freestep - 06/26/11 14:07 Hi Borderline Can you please email the nbme form 11 and 12? I need them for practice. Thanks. My email kchall78@yahoo.com hi maryam, can u please explain q # 21... how ? Report Abuse * Re:NBME 12 section 3 answers. #2434712 jagadish - 07/21/11 05:23 maryan and borderline thanks a lot.... Report Abuse * Re:NBME 12 section 3 answers. #2463523 drnash - 09/03/11 03:16 For Question 30...the Base 'g' belongs to the codon AGg which will now become AGA and it doesnt belong to the next codon and therefore it will not lead to ATT Formation..[All codons will be in multiples of 3...hence in the starting of line count from the number 241+242+243=1 codon[till previous line 240 bases means 80 codons completed]..244+245+246=2nd codon...hence the answer has to to domething with AAAA sequence that came in Option c...may be Poly A tail and hence premature termination of Transcription..hence shorter Proteins and hence Thalassemia.. Report Abuse * Re:NBME 12 section 3 answers. #2463599 doitnow - 09/03/11 09:43 hi border?! how u been. thank you very much as usual.please can u send me the nbme 12 questions ? the one i have it could not be open.my email isibedria@yahoo.com.thank you Report Abuse * Re:NBME 12 section 3 answers. #2513237 mmusmle - 10/29/11 18:43 For q 30 answer is B as leading to formation of stop codon In the online exam I chose C and it was wrong Report Abuse * Re:NBME 12 section 3 answers. #2523562 champion99 - 11/14/11 07:13 please who can give me an explanation for number 41---really thought i was doing well but then i just discovered this was the block that pulled my scores low----i got a 460--corresponding to a 212----my exm is on the 27th o December---wiill appreciate your comments Report Abuse * Re:NBME 12 section 3 answers.

* Re:NBME 12 section 3 answers. #2523562 champion99 - 11/14/11 07:13 please who can give me an explanation for number 41---really thought i was doing well but then i just discovered this was the block that pulled my scores low----i got a 460--corresponding to a 212----my exm is on the 27th o December---wiill appreciate your comments Report Abuse * Re:NBME 12 section 3 answers. #2523609 syndrome111 - 11/14/11 09:59 hello borderline.. do you have answers for other blocks of NBME 12? if so , can you pls post them .. or anyone who has nbme 12 answers pls post here .. ur efforts appreciated ..GL NBME 12 answers --------------------------------------NBME 12 answers by jdoc208 -------------------------------------section 1 1. BAEDF 6. EBBCD 11. BBAFE 16. BADAA 21. AAAEA 26. CECAC 31. AFBBC 36. EADAD 41. DEDCC 46. CEGDF --------------------------------------------section 2 1. EBAAA 6. CEEFC 11. CBDBD 16. DCCEF 21. AACEC 26. EDEEB 31. CAADD 36. EBDDC 41. ADDCD 46. ADFBC ------------------------------------------section 3 1. ECAEE 6. BBCDC 11. BAEBA 16. CACCD 21. DEEDB 26. CCEFB 31. BADDC 36. CDDBA 41. AADBB 46. AADDA

1. ECAEE 6. BBCDC 11. BAEBA 16. CACCD 21. DEEDB 26. CCEFB 31. BADDC 36. CDDBA 41. AADBB 46. AADDA ----------------------------------------section 4 1. AAEDE 6. BDECB 11. DADCC 16. ACBEE 21. CADAB 26. CDADC 31. CECBC 36. CADAC 41. DDDDB 46. DDCAF correction 26.D 29.C

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