Generic Name: Amoxicillin Brand Name: Amoxil, Polymox Classification: Non-narcotic analgesic, Antipyretic,Antibiotic

Uses 1. Ear, nose, and throat infections due to Streptococcus species. 2. GU Infections due to Escherichia coli, Proteus miribalis, Enterococcus facecalis. 3. Skin infections due to Streptococcus, S. pneumonia, Staphylococcus, or H. haemophilus 4. Acute uncomplicated gonococcal infections due to Neisseria gonorrhoeae. 5. In combination with omeprazole or lansoprazole to treat duodenal ulcers by eradicating Helicobacter pylori. Actions: This drug is a semi-synthetic broad spectrum penicillin closely related to Ampicillin. It binds to Penicillin-binding proteins in the cytoplasmic membranes of bacteria, thus inhibiting cell-wall synthesis. It also inhibits cell growth and cell division. It is better absorbed than Ampicillin. Contraindications: 1. Hypersensitivity 2. Use of the 875mg tablet in clients with a GFR less than 30mL/minute. Special Concerns: 1. Safe use during pregnancy has not been established. 2. Drug may decrease effectiveness of oral contraceptives. Side-Effects: 1. Hypersensitivity 2. Nausea 3. Vomiting 4. Gastritis 5. Stomatitis

Dosage: Per Orem: usual dose of 500mg q8h or 500mg q12h. For gonococcal infections: 3 grams single dose. Nursing Considerations: 1. Note for any hypersensitivity reaction 2. Instruct clients that therapeutic regimen must be completed even if symptoms subside. 3. Childs dose should not exceed maximum adult dose. 4. Clients with GFR of 10-30 mL/min should receive 250-500mg q12h. 5. Monitor CBC, renal and liver function tests. 6. May be taken with food. 7. Antibiotic resistance may occur if used without practitioner consultation as duration of therapy may not be completed. Report: bleeding, sore throat, rash, diarrhea, worsening of symptoms, lack of response.

Generic Name:Mebendazole Brand Name:Vermox Classifications: antiinfective; anthelmintic Pregnancy Category: C Availability 100 mg tablets Actions Carbamate with unusually broad spectrum of anthelmintic activity. Mechanism of action not known. Therapeutic effects Inhibits formation of worms microtubules and inhibits glucose and other nutrient uptake by susceptible helminths. Uses Treatment of Trichuris trichiura (whipworm), Enterobius vermicularis (pinworm), Ascaris lumbricoides (roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.

Contraindication Safety during pregnancy (category C), lactation, or in children <2 y is not established. Route & Dosage Enterobiasis adult:PO 100 mg as single dose child:PO 100 mg as single dose Other Infestations adult:PO 100 mg b.i.d. times 3 d child:PO 100 mg b.i.d. times 3 d Administration Oral 6. Allow tablets to be chewed and swallowed, or crushed and mixed with food if needed. Adverse effects GI:Transient abdominal pain, diarrhea. BodyWhole:Dizziness, fever (possibly due to tissue necrosis in cysts). Nursing implications Assessment & Drug Effects

3. Initiate second course of treatment if cure does not occur within 3 wk. 4. Examine and treat all family members simultaneously because pinworms are readily transmitted from person to person.

Patient & Family Education 3. Practice thorough hand washing after touching any potentially contaminated item. 4. Change underclothing, bedclothes, towels, and facecloths daily; bathe frequently, preferably by showering. Infected person should sleep alone. Do not breast feed while taking this drug without consulting physician.