SN PHM DU GI V TON THN C HOT CHT GY MT MENTHOL

2.1 NGUYN TC Sau nhng gi lm vic cc nhc, ngi tiu dng ngoi nhu cu tm gi sch s , cn thch sn phm to cm gic d chu qua s gy mt Methol v mt s dn xut ester t Methol p ng nhu cu ny. 2.2 CNG THC PHI CH Tng A Nguyn liu - Sodium lauryl sulfate (SLAS 3035%) - Cocoaminopropyl betain (CAPB) - Methylparaben - Propylparaben - Nc deion - Polyquaterium-10 RM 12.00 2.00 0.50 V/d 100 0.40 0.40 0.20 20.00 0.40 1.00 0.70 Chc nng - Cht hot ng b mt chnh l lm sch cht bn. - Cht HBM ph tr. - St vi khun. - St vi khun. - Dung mi - Chng ri ( trung ha in tch m.) - Lm c gel ( dng in ly) - Mu gy hp lc. - Lm c ( dng polymer) - Gy hp lc - Gy mt - To lp du mng trn da v tc .
Tng B

- Sodium chloride - Brilliant blue 0.1% - Carbopol dd 2% - Hng C - Methol - PEG 25 hydrogenated castor oil 2.3 S PHI CH
Tng A

Khuy , to gel

Thm ph gia , khuy

n nh

Ra bao b

CCH TIN HNH - Phn A : Tch mt lng nc ngm , khuy SLAS ha tan hon ton ri khy trn tt c cc nguyn liu trong A hn ha vo nhau . - Phn B : Ha tan polyquaternium 10 vo phn nc cn li , va cho va khuy . Tip tc cho nhng nguyn liu khc trong B vo v khuy u ri cho vo phn A , va cho va khuy . - Phn C : Thm tip C vo v khuy n khi ng nht. 2.4 PHNG TIN PHI CH 2.4.1 DNG C Bercher 250 Bercher 100 ng ong 100

02 03 01

a nha nh 05 Mung nha nh 05 Bnh cha nc ct 01 2.4.2 THIT B B iu nhit 01 Cn in 2 s thp phn 01 My pH (hoc giy pH Beckman) 01 My khy c 01 Cnh khuy 01 Bp in knh nh 01 1.4.3 HA CHT Tnh cho mi nhm 3 sinh vin , da vo n phi ch 2.5 PHNG TIN NH GI 2.5.1 NH GI HOT TNH GY MT - Vng th : tc ( da u ) - Lng ngi th : 32 ngi ( nam , n , trong cc gii s , nng , cng , thng ) NH GI KH NNG GY MT SN PHM kin 1. nh gi s chp nhn kh nng gy mt C Khng ca sp/pc 2. nh gi thi gian gy mt lnh ca sp/pc 25 Z Thi gian gy mt lnh /sp (pht) 20 15 10 5

3. nh gi cng gy mt ca sp/pc

R.mnh

Cng gy mt ca sp Mnh T.Bnh Yu

Khng

Ph ch : thang im nh gi Thi gian gy mt ( pht)

10

15

20

25

Cng gy mt

khng

yu

Trung bnh

Mnh

Rt mnh

im

d thc hin xin xem qua th d sau : Bng 1 : Ch tiu nh gi S chp nhn kh Tng lp S N S ngi / tng lp 8 8 S ngi / s chp nhn Chp nhn 4 8 Khng chp nhn 4 0 Phn b (%) Chp nhn 50 100 Khng chp nhn 50 0

nng gy mt Bng 2 : Ch tiu Tng nh lp gi S Thi N gian C gy T mt Tng Bng 3 : Ch tiu nh gi Cng gy mt Tng lp S N C T Tng

C T Tng S ngi / tng lp 8 8 8 8 32 S ngi / tng lp 8 8 8 8 32

8 8 32

8 8 28

0 0 4

100 100 87.5

0 0 12.5 im trung bnh 1.12 3.62 1.75 2.25 2.19 im trung bnh 2.50 3.88 3.25 3.38 3.25

S ngi / thi gian gy mt ( pht) 25 0 0 0 0 0 20 0 5 0 0 5 15 1 3 1 3 8 10 3 0 4 4 11 5 0 0 3 1 2

S ngi / thi gian gy mt ( pht) Rt mnh 0 0 0 0 0 Mnh 4 7 3 3 17 Trung bnh 0 1 4 5 10 Yu 0 0 1 0 1 Khng 4 0 0 0 4

2.5.2 KIM TRA DU GI ( theo tiu chun B Y T Phn vin kim nghim) CH TIU 1. NGOI QUAN - Trng thi - Mu sc - Mi 2.HA L 1. n nh trng thi khi thay i nhit 10oC 2oC v 45oC 2oC 2. Hm lng cht hot ng b mt tan trong cn. 3. Hm lng mui clorid (qui ra NaCl) 4. Hm lng ammonia t do 5. pH dung dch 10% trong nc 6. Th tch ct bt dung dch 1% trong nc 7. n nh bt - sau 3ph - sau 5ph 8. Cht hot ng b mt DBSA 9. Chnh lch th tch 10. nh tnh cc hot cht chnh 11. nh lng cc hot cht chnh 3. V SINH AN TON - Gii hn kim loi nng - Gii hn Arsen - nhim khun - Kch ng da MC YU CU - Lng snh , ng nht khng tch lp , phn tng. - Mu ng nht. - Thm d chu - Khng thay i - 10% - 2% - 0.1% - 4 - 7.5 - 350ml - 95% - 90% - Khng c c - 95% th tch nhn - ng - Phi t - 2 ppm (TCVN 5817-1994) - 1 ppm (TCVN 5817-1994) - t yu cu ( TC B y t 3113/99/QBYT) - t yu cu ( TC B y t 3113/99/QBYT)