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Neutrophilia may be
accompanied by fever due
to the release of Leukocyte
pyrogens
Reactive Neutrophilia
metamyelocytes)
Reactive changes in neutrophils
Underlying disease:
MPO +ve
LAP +ve in CML
“Shift to the Left”
Malignancies of the leukocytes
LEUKAEMIA
it is the malignant proliferation of the WBC, with the presence of the immature
MYELOMA
producing cells.
LEUKEMIA
Definition
Leukemia is a type of cancer. It is the cancer of the blood cells.
Leukemia
When leukemia develops, the body produces large numbers of
abnormal blood cells.
The leukemia cells usually look different from normal blood cells,
and they do not function properly.
Causes of leukemia
Leukemia occurs more often in males than in females and
In white people more often than in black people.
Certain risk factors increase a person's chance of developing
leukemia. For example,
Exposure to large amounts of high-energy radiation.
Exposure to electromagnetic fields is a possible risk factor
(Electromagnetic fields are a type of low-energy radiation that
comes from power lines and electric appliances.)
Certain genetic conditions can increase the risk for leukemia.
One such condition is Down's syndrome. Children born with this
syndrome are more likely to get leukemia than other children.
Workers exposed to certain chemicals over a long period of time.
Benzene is one of these chemicals.
Anti cancer drugs
Types of leukemia
This disease also affects adults, especially those age 65 and older.