Pathology 2009-2010 MBBS MCQs

1. Fibrocystic changes
a) is the most common breast disorder in women
b) is due to abnormal response to ovarian hormones
c) is associated with in-situ carcinoma
d) has high risk of developing breast cancer
e) is also known as fibroadenoma.

2. Endometrial cancer is
a) associated with use of intrauterine contraceptive device
b) associated with excess estrogen
c) obesity as a risk factor
d) clear cell CA is the most common
e) associated with HPV infection

3. In the area of molecular pathology and molecular diagnosis,

a) The detection of monoclonality is essential in diagnosing biopsy samples of
breast cancer.
b) Microsomal instability are helpful in diagnosing HNPCC
c) The detection of monoclonality is essential in diagnosing biopsy samples of
lymphomas
d) HER2-neu gene detection by FISH test is used to diagnose inherited breast
cancer
e) FAP is caused by mutations in the mis-match repair genes.

4. Granulomas
a) are mainly compose of macrophages, epitheloid cells and lymphocytes
b) are always caused by infections
c) are mediated by CD4+T lymphocytes
d) are mediated by IL-2 and alpha IFN
e) always contain area of central necrosis

5. The sequence of metaplasia-dysplasia-neoplasia occurs in the neogenesis of

a) squamous cell carcinoma bladder
b) carcinoid of the small intestine
c) adenocarcinoma of the Barret's oesphagus
d) squamous cell carcinoma of the lungs
e) malignant lymphoma

6. In acute inflammation
a) decreased blood flow to affected part
b) increased vascular permeability to proteins
c) is associated with local 5 hydroxytrytamine release
d) caused by mechanical trauma
e) a manifestation of the ability of normal tissues to respond to damage
7. Regarding Osteoarthritis
a) cartilage fibrillation
b) pannus formation
c) eburnation of bone
d) herberden's nodes
e) osteophyte formation

8. Macrophages
a) play a role in graft rejection
b) are involved in antigen recognition
c) Have membrane receptors for Fc fragment of antibodies
d) Is involved in type 4 hypersensitivity
e) Have no phagocytic properties

9. Low grade lymphomas:

a) Incurable
b) monoclonal proliferation of large lymphoid cells
c) clinically aggressive

10.

11. Which of the following helps in the grading of a tumor?

a) the presence or absence of metastases in the lymph node
b) the degree of differentiation
c) the presence of tumor necrosis
d) mitotic activity
e) the presence of cells in the vascular spaces

12. Successful healing of long bones depends upon:

a) apposition of the fragments
b) Surgical removal of the hematoma
c) Free mobility of the limb
d) The absence of infection
e) Elevation of the limb

13. Small cell carcinoma of the lung is:

a. Is not associated with cigarette smoking.
b. Is usually found in the periphery of the lung.
c. Is more common in women than men.
d. Often produces ectopic hormones
e. Has a poor prognosis.

14. Adult respiratory distress syndrome:

a) pulmonary edema is a feature
b) hyaline membrane is present in alveoli
 c) has a high mortality
d) associated with acute pancreatitis
e) can occur following diffuse alveolar injury

15.

16. Fall in blood pH from 7.40 to 7.10

a) represents an approximate doubling of H+ concentration
b) characteristically caused by persistent vomiting
c) characteristically caused by hyperventilation
d) can be accompanied by elevated serum potassium
e) is incompatible with life

17. What of the following causes elevated total CSF protein:

a) CNS tumour
b) CVA
c) Epilepsy
d) Viral meningitis
e) CNS trauma

18. H Pylori
a) associated with gastric carcinoma and lymphoma
b) causes a chronic lymphoid infiltration
c) is a urea-producing organism
d) is usually found in areas of intestinal metaplasia
e) causes a chronic gastritis by invading the mucosal epithelium

19. Pseudomembranous Colitis

a) caused by clostridium difficile toxin
b) is present in immunosuppressed individuals
c) toxin mediated injury causes epithelial shedding and necrosis
d) pseudomembranes present by desloughing of epithelium
e) associated with antibiotic use

20. Concerning SLE

a) circulating immune complexes responsible for glomerulonephritis
b) absolute increase in T suppressor cells
c) renal biopsy seldom required for directing therapy
d) renal biopsy includes active diffuse proliferating glomerulonephritis
e) ITP can be initial manifestation of SLE

Please feel free to contact for further data of fallowing universities

Fees, admission, classes, environment
http://pakdata.net
Shahzad.cdcu@gmail.com
• National Defence University, Islamabad
• Virtual University of Pakistan, Lahore
• National University of Science and Technology, Rawalpindi
• Quaid-e-Azam University, Islamabad
• Pakistan Institute of Development Economics, Islamabad
• Pakistan Institute of Engineering & Applied Sciences, Islamabad
• National University of Modern Languages, Islamabad
• International Islamic University, Islamabad
• Institute of Space Technology (IST), Islamabad
• Federal Urdu University of Arts, Science and Technology, Islamabad and Karachi
• COMSATS Institute of Information Technology, Islamabad
• Bahria University, Islamabad
• Allama Iqbal Open University, Islamabad
• Air University, Islamabad
• Riphah International University, Islamabad
• National University of Computer and Emerging Sciences, Islamabad
• Foundation University, Rawalpindi
• Center for Advanced Studies in Engineering, Islamabad
• University of Azad Jammu and Kashmir, Muzaffarabad
• Mohi-ud-Din Islamic University, Nerian Sharif AJK
• Al-Khair University (Mir Pur AJK),
• Bolan University of Medical & Health Sciences, Quetta
• Balochistan University of Engineering and Technology, Khuzdar
• Balochistan University of Information Technology, Engineering and Management
Sciences, Quetta
• Lasbela University of Agriculture, Water & Marine Science, Lasbela
• Sardar Bahadur Khan Women University, Quetta
• University of Balochistan, Quetta
• Institute of Management Sciences (IMSciences), Hayatabad
• Frontier Women University, Peshawar
• Gomal University, Dera Ismail Khan
• Islamia College University, Peshawar
• Kohat University of Science & Technology, Kohat
• Khyber University of Medical and Health Sciences, Peshawar
• NWFP Agricultural University, Peshawar
• Pakistan Military Academy, Abbotabad
• The University of Science & Tecnology, Bannu
• University of Engineering and Technology (NWFP), Peshawar
• University of Hazara, Hazara
• University of Malakand, Chakdara
• University of Peshawar, Peshawar
• Qurtaba University of Science & Information Technology, D. I. Khan, Peshawar
• CECOS University of Information Technology and Emerging Sciences, Peshawar
• City University of Science and Information Technology, Peshawar
• Gandhara University, Peshawar
• Ghulam Ishaq Khan Institute of Engineering Sciences and Technology, Swabi
• Northern University, Nowshera
• Preston University, Kohat
• Sarhad University of Science and Information Technology, Peshawar
• Abasyn University, Peshawar
• Gandhara College of Arts, Peshawar
• Karakurum International University, Gilgit
• Allama Iqbal Open University, Gilgit
• Bahauddin Zakariya University, Multan

King Edward Medical University, Lahore

• Fatima Jinnah Women University, Rawalpindi

• Government College University, Lahore

Lahore University of Management Sciences

• Government College University, Faisalabad

• The Islamia University of Bahawalpur, Bahawalpur
• Kinnaird College for Women, Lahore
• King Edward Medical College, Lahore
• Lahore College for Women University, Lahore
• National College of Arts, Lahore
• National Textile University, Faisalabad
• University of Agriculture, Faisalabad
• University of Arid Agriculture, Rawalpindi
• University of Education, Lahore
• University of Engineering and Technology, Lahore, Faisalabad
• University of Engineering and Technology,Taxila
• University of Health Sciences, Lahore
• University of Gujrat, Gujrat
• University of the Punjab, Lahore, Gujranwala
• University of Sargodha, Sargodha
• University of Veterinary and Animal Sciences, Lahore
• Virtual University of Pakistan, Lahore
• Hajvery University, Lahore
• Beaconhouse National University, Lahore
• Forman Christian College, Lahore
• GIFT University, Gujranwala
• Imperial College of Business Studies, Lahore
• Institute of Management Sciences, Lahore, Pak-AIMS, Lahore
• Lahore School of Economics, Lahore
• Lahore University of Management Sciences, Lahore
• Minhaj International University, Lahore
• National College of Business Administration and Economics, Lahore
• School of Business & Commerce, Rawalpindi
• University Of Management and Technology, Lahore
• University of Central Punjab, Lahore
• University of Faisalabad, Faisalabad
• University of Lahore, Lahore
• University of South Asia, Lahore
• Superior University, Lahore
• International Islamic University, Bahawalpur
• University College Lahore, Lahore
• University of Munawwar-ul-islam.Gujrat
• Bahria University, Karachi Campus
• Dawood College of Engineering and Technology,Karachi
• Dow University of Health Sciences, Karachi
• Institute of Business Administration, Karachi
• Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad
• Mehran University of Engineering and Technology, Jamshoro, Hyderabad
• NED University of Engineering & Technology, Karachi
• Pakistan Naval Academy, Karachi
• Quaid-e-Awam University of Engineering, Science and Technology, Nawabshah
• Shah Abdul Latif Bhitai University, Khairpur
• Sindh Agriculture University, Tandojam
• Institute of Business Administration (IBA) Sukkur
• University of Karachi, Karachi
• University of Sindh, Jamshoro, Hyderabad
• Aga Khan University, Karachi
• Baqai Medical University, Karachi
• Dadabhoy Institute of Higher Education, Karachi
• DHA Suffa University, Karachi
• Greenwich University, Karachi
• Hamdard University, Karachi
• Indus Institute of Higher Education, Karachi
• Indus Valley School of Art and Architecture, Karachi
• National University of Computer and Emerging Sciences, formerly FAST Institute of
Computer Science Karachi Campus
• Institute of Business & Technology (BIZTEK), Karachi
• Institute of Business Management, Karachi
• Iqra University, Karachi
• Isra University, Hyderabad
• Jinnah University for Women, Karachi
• Karachi Institute of Economics & Technology (PAF KIET), Karachi
• KASB Institute of Information Technology, Karachi
• Mohammad Ali Jinnah University, Karachi
• Nazeer Hussain University, Karachi
• Newports Institute of Communications and Economics, Karachi
• Preston Institute of Management Sciences and Technology, Karachi
• Preston University, Karachi
• Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology, Karachi
• Sir Syed University of Engineering and Technology, Karachi
• Textile Institute of Pakistan, Karachi
• University of East, Hyderabad
• Ziauddin Medical University, Karachi
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