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DIABETES INSIPIDUS

Central/neurogenic cause Nephrogenic cause

Decreased ADH secretion

Kidney tubules fail to reabsorb water Plasma hyperosmolarity

Increased urination of dilute urine Stimulate thirst center


Nocturia, decreased urine specific gravity
Dec. BP, (+) water dehydration

Polydipsia

N4-Group8 Diabetes Insipidus Pathophysiologic Diagram lmmeyusuf

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