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PATIENT IDENTITY
Medical Record : 629171 Name : Mr. M Gender : Male Age : 62 years old Date of admission : September 22nd 2013
HISTORY TAKING
Chief Complain : Chest Pain Structural Anamnesis: Occurred since about 7 hours before admitted to the hospital. On the left side the chest pain feels dull heavy pain, it seems to radiates to the back. It does not radiate to the shoulder/arm. Chest pain last for 30 minutes. The pain is not lessen at rest or with medication. Patient had experienced chest pain for a year long.However, patient did not check it to the hospital, because at that time the pain it did not disturb his everyday activities and lessen at rest. The chest pain accompanied with shortness of breath, cold sweat (+), fever (-), cough (-), nausea (+), vomit (+), epigastric pain (-). Defecation and urination normal.
HISTORY TAKING
History of Past Illness:
History of chest pain before (+) No history of heart disease No family history of heart disease No History of diabetes mellitus No history of dyslipidemia No history of asthma No history of epigastric pain
PHYSICAL EXAMINATION
General Status Moderate Ilness/ Overweight/Conscious Body Weight :70 kg Body Height :170 cm Body Mass Index : 24,2 kg/m2 Vital Signs BP : 150/100mmHg HR : 96 bpm, regular RR : 28 bpm T : 36,5C
PHYSICAL EXAMINATION
Head and Neck Examinations: Eye : Conjunctiva anemic (-/-), Sclera icteric (-/-) Lip : Cyanosis (-) Neck : JVP R +2 cmHO Chest Examination Inspection Palpation Percussion
: Symmetric between left and right chest. : No mass, no tenderness. : Sonor between left and right chest, lungliver border in ICS IV right anterior . Auscultation : Breath Sounds : Vesicular Adventitious breath sound : Ronchi -/-, wheezing -/-
PHYSICAL EXAMINATION
Cardiac Examination Inspection : Heart apex was not visible Palpation : Heart apex was not palpable Percussion : Dull, left heart border left midclavicular line ICS V. Auscultation : Heart Sounds : S I/II regular, murmur (-) gallop(-)
PHYSICAL EXAMINATION
Abdominal Examination
Insp. Ausc. Palp. Perc. : Flat and following breath movement : Peristaltic sound (+), normal : Liver and spleen is unpalpable : Tympani (+), ascites (-)
Extremities
Oedema : Pretibial -/-, Dorsum pedis -/-
ELECTROCARDIOGRAM (ECG)
ECG :Sinus rhythm, QRS rate 83 bites/ minute, north west axis, PR interval 0,16 s, P wave 0,08 s, QRS comlex 0,08 s, Q patologis III, aVF, V1-V3 ST segment elevation V1-V5 Conclution : sinus rhythm, HR 83 bite/minute, whole anterior acute myocard infraction , old myocard infraction inferior
ELECTROCARDIOGRAM (ECG)
ECG :Sinus rhythm, QRS rate 93 bites/ minute, right axis devilation, PR interval 0,12 s, P wave 0,08 s, QRS comlex 0,08 s, Q patologis in III, aVF, V1-V3 ST segment elevation in V1-V5 Conclution : sinus rhythm, HR 93 bite/minute, whole anterior acute myocard infraction , old myocard infraction inferior
Laboratorium Finding
Complete blood count
Test WBC RBC HGB HCT PLT Result 9,05 x 103/ul 4.86 x 106/l 15.0 gr/dl 44,6 % 141 x 103 /l Normal value 4.0 10.0 x 103 4.0 6.0 x 106 12 16 37 48 150 400 x 103
Blood Chemistry
Test GDS Ureum Creatinine SGOT SGPT Total Chol HDL Chol LDL Chol Result 141 mg/dl 33mg/dl 0,9 mgr/dl 24u/l 21 u/l 123 mg/dl 23mg/dl 99 mg/dl Normal value <140 10 50 < 1.3 <38 <41 <200 > 55 < 130
Cardiac Enzymes
Test CK CK-MB Troponin-T Result 211U/L 10 U/L <0.02 Normal value <190 <25 <0,05
Electrolyte
Test Result Normal value
Na
K Cl
145 mmol/l
3.5 mmol/l 110 mmol/l
136-145
3.5-5.1 97-111
CHEST X-RAYS
Cloudy parahilar accompanied with cardiovascular suprahilar dilatation on both lungs There is no specific active process seen on both lungs Cor CTI widen 0,57 cm, aorta dilated and calcified Both sinuses and diaphragma in good condition Bones intact Impression: Cardiomegaly with signs of Pulmonary edema dilatation et atherosclerosis aorta
WORKING DIAGNOSIS
1. ST elevation myocardial infarction (STEMI) whole anterior onset >6 hours KILLIP I, 2. Old myocard infraction inferior 3. Grade I hypertension
MANAGEMENT
O2 2 -4 Lpm IVFD NaCl 0,9% 10 drops/min Aspilet 80 mg 0-1-0 Aspirin (Antiplatelet) Plavix 75 mg 0-0-1 Clopidogrel (Antiplatelet) Injection ISDN 0,5 mg/hours/SP Nitrat Captopril 25 mg 1-1-1 ACE-Inhibitor Simvastatin 20 mg 0-0-1 Statin (Anticholesterol) Alprazolam 0,5 mg 0-0-1 Antianxietas Laxadyn syr 0-0-2 c
PLANNING
Coronary angiography
DEFINITION
Myocardial infarction (MI) rapid development of myocardial necrosis caused by a critical imbalance between the oxygen supply and demand of the myocardium. This usually results from plaque rupture with thrombus formation in a coronary vessels, resulting in an acute reduction of blood supply to a portion of the myocardium.
PATHOPHYSIOLOGY
Occurs when coronary
blood flow decreases abruptly after a thrombotic occlusion of a coronary artery previously affected by atherosclerosis. In most cases, infarction occurs when an atherosclerotic plaque fissures, ruptures, or ulcerates.
PATHOGENESIS
Lipid transport disorder Inflamation Plaque deposition
Stable plaque
Thrombus
Erosion
Plaque rupture
Acute coronary syndrome: Unstable angina Myocardial infarction : - Non Q waves - Q waves
Thrombosis
RISK FACTOR
Non- Modifiable
Gender and Age Men, increased risk after age 45 Women, increased risk after age 55 Family History Heart disease diagnosed before age 55 in father or brother Heart disease diagnosed before
Modifiable
Smoking
Hypertension Diabetes Mellitus Dyslipidemia Obesity Lack of physical activity
CLINICAL MANIFESTASION
Prolonged pain (usually >20 minutes) constricting, crushing, squeezing
ECG CHANGES
Timing of myocardial infarction based on ECG
Myoglobin
SGOT
DIAGNOSIS
Signs of myocardial ischemia ECG
Yes
ST segmen elevation ?
STEMI
No
Lab
Yes
No
Unstable Angina
INITIAL TREATMENT
1. 2. 3. 4. Bed Rest Diet Oxygen (2-4L/mnt) Anti platelet therapy :
Aspirin 160-325 mg chewed immediately and 81-162 mg continued indefinitely. Clopidogrel 300-600 mg loading dose and 75 mg daily continued for at least 14 days and up to 12 months
INITIAL TREATMENT
6. Morphine 2,5-5 mg or pethidin 12,5-25 mg iv 7. ACE I (Captopril 12,5-25 mg ) 8. Fibrinolytic therapy: a) Streptokinase 1.5million units iv b) Tenecteplase 0.5mg/kg body weight iv. 9. Anticoagulation therapy: a) Low Molecular Weight Heparins ( Fondaparinux) 2.5mg/24hrs/sc for up to 8 days post-MI. 10. Statins Simvastatin 20 mg
Total Score
0 1 2 3 4 5 6 7 8 9-14
Risk of Death in 30 days 0.8% 1.6% 2.2% 4.4% 7.3% 12.4% 16.1% 23.4% 26.8% 35.9%
3 points
2 points 2 points 1 point 1 point 1 point (0-14)
Presentation
Anterior STE or LBBB Time to treatment > 4 hrs Risk Score = Total
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