Subject: Medical Sciences Book Index: The H.E.R.B.A.L. Guide Dieta ! Su""le#ent Resou ces $o the %linician b!

Robe t Alan Bonakda St!le: %hica&o Manual o$ St!le' Indented

A ABC Clinical Guide to Herbs, ()* Abo tion' black ha+ and c a#" ba k $o ' ,(-.,(( Acne causes' (/0 classi$ication' (/0 clinical $eatu es' (/0 dieta ! su""le#ent $o ' (/) eactions and inte actions' (//.(/1 eco##endations' (// "atient education botanicals and nut aceuticals' (/) esou ces' (/1.(/2 "atient listenin&' (/3.(/) " e4alence' (/0 t eat#ent discussion and $ollo+5u"' (/1 usin& antibiotics' (/0.(/3 AD567' ,0, Ad4e se e4ent e"o tin&' ((( b! dieta ! su""le#ent #anu$actu e s' )2./* le&islation' 30.33 The AER la+. See Dieta ! Su""le#ent and 8on" esc i"tion D u& %onsu#e 9 otection Act :(**); Alk Abello. See G a<ax Alle &ic hinitis' natu al #edicines $o ' ,00.,03 Al"ha5G9% :Al"ha Gl!ce ol 9hos"ho !l %holine;' ,0/ Al"ha5linolenic acid' ,*/' ,/( Al"ha5li"oic acid' (2*.(2Alte nati4e #edicine. See also %o#"le#enta ! and alte nati4e #edicine :%AM; de$inition' () &o4e n#ent in$o #ation esou ces' (33 AltMedDex' (3, Aluta d S=' ,03 A#e ican Dietetic Association' (((.((, A#e ican &insen&

$o cold and $lu " e4ention' ,3) inte action +ith d u&s' -3) A#e ican He balists Guild :AHG;' (*3.(*) A#e ican He bal 9ha #aco"oeia' ()A#e ican Medical Association :AMA;' (*, A#e ican Societ! $o 8ut ition :AS8;' --/.--1 Antioxidants' ,10 Anxiet!' natu al #edicines $o ' ,01.,02 Arctostaphylos uva-ursi. See >4a5u si A tichoke lea$ ext act' ,/3 Asparagus racemosus, ,() Aust alian e&ulation o$ he bal #edicines co#"le#enta ! #edicines' 1) eli&ible listable in& edients' 1/ ins"ections' 11 e&ulato ! &uidelines' 1/.11 " o#otion?ad4e tise#ents' 11 as @the a"eutic &oods'A 1) B Bea be !. See >4a5u si Beni&n " ostatic h!"e "lasia :B9H; clinical $eatu es' (1* dieta ! su""le#ent $o beta5sitoste ol' (1(' ,3, 9 ostActi4e 9lus' ,3, "u#"kin seed oil ext act' ,3, "!&eu#' (1(.(1,' ,3, eco##endations o$' (1,.(10 !e & ass "ollen ext act' (1, sa+ "al#etto' (1(' ,3( side e$$ects o$' (10 "atient education li$est!le choices' (1nut itional chan&es' (1( esou ce $o e4idence5based in$o #ation' (13 "atient listenin& #edical histo !' (1* t eat#ent and li$est!le histo !' (1t eat#ent discussion and $ollo+5u"' (10 Beta5sitoste ol' (1(' (1,' ,3, Bi$idobacte ia' ,/3 Bioelect o#a&netic5based the a"ies' (/ Bio$ield the a"ies' (/ Biote o is# Act o$ (**(' )( Bitte o an&e

ca diac toxicit!' -0).-0/ inte action +ith d u&s' -3) Black cohosh he"atotoxicit!' -0/ inte action +ith d u&s' -3) $o #eno"ause " e4ention' ,/2 as "a tus " e"a ato ' ,(0 Black ha+' ,(-.,(( Blond "s!lliu# $o diabetes " e4ention' ,)( $o h!"e choleste ole#ia " e4ention' ,*/.,*1 $o :" e;h!"e tension " e4ention' ,*/ and statins' (-Botanical ext acts bioacti4es in' -)2 clinical studies' -)2 containin& constituents +ith the a"eutic acti4it!' -1).-1/ dose5to5dose eliabilit! DART TB65MS $in&e " ints' -/*.-/( elde be ! and tu #e ic' -/( 4alidation' -/, health bene$its' -/, Botanical &a dens #edicinal i#"o tance o$' -)).-)/ =BG' MBG' and 8CBG' -)/ easons $o c eation o$' -)1 Botanical " oducts bioeDui4alence o$' -2* clinicall! tested' -12.-2* &uidance on cha acte i<ation o$' -11 Dualit! cont ol' 13 e&ulation' -11 the a"eutic bene$it' -13 the a"eutic eDui4alenc! o$' -2* Botanical Resea ch %ente s 9 o& a#' -2).-2/ B east cance ' natu al #edicines $o ' /)' ,30 B east$eedin&' bene$its o$' ,(3 British Herbal Pharmacopoeia, 22 Butte bu lea$ and oot ext act' ,00 $o #i& aine " e4ention' ,**' ,)/ % %alciu# ca bonate tablets' /, %alciu# su""le#entation' ,2 $o osteo"o osis " e4ention' ,13.,1)

$o " e#enst ual s!nd o#e " e4ention' ,1/ %ali$o nia Health and Sa$et! %ode' 3( %ali$o nia Sa$e D inkin& Eate and Toxic En$o ce#ent Act o$ -21)' )) %AMline' (30 %anadian e&ulation o$ 8H9s in $ood $o #at' 2*.2#a ketin&' 2* b! 8H9D' 12 NHP egulations. See Natural Health Product egulations !NHP egulations" %ance and DS use' 0/ health clai#s $o " e4ention o$' /3./) %a"saicin' ,)3 $o lo+ back "ain " e4ention' ,-)' ,// Capsicum #rutescens. See %a"saicin %a nitine $o #ulations' ,0)' ,3-' ,31' ,), %ata acts' natu al #edicines $o ' ,33 %et!lated $att! acids' ,10 %hastebe !' ,11 %hond oitin su""le#ents' Dualit! " oble# +ith' -(1 %h o#iu# "icolinate' (12' (2-' ,)( Cimici#uga racemosa. See Black cohosh Citrus aurantium. See Bitte o an&e %linical t ials' -/) botanicals in " e&nant +o#en' ,-2.,(Echinacea " e"a ations' -1he bal ad4e se eactions' -0).-02 Dualit! o$' -/3 atin& scales $o e4aluatin&' -/3 e&ulato ! o4e si&ht o$' 2e"o t e4aluation' -/2 %linician."atient discussion. See also 9atient educationF 9atient listenin& %AM use' ,DS use' 0/ ste"s encou a&in&' 3.) %ocoa $lo+5#ediated dilation +ith' ,*2 $o h!"e tension " e4ention' ,*2' ,/( %oen<!#e =-* :%o=-*;' ,31 $o diabetes " e4ention' (2*' (2$o #i& aine " e4ention' ,**' ,)1 %old and $lu' natu al #edicines $o ' ,3).,3/ %o#edonal acne' (/0 %o#"le#enta ! and alte nati4e #edicine :%AM;' (3 biolo&icall! based " actices in' (/ cate&o ies' ().(/

lite atu e' -/3 #ani"ulati4e and bod!5based " actices in' (/ " otocols $o handlin& "atients usin&' 30 use b! a&e' ,( based on conditions' (2' ,based on de#o& a"hics' (2' ,( natu al " oducts' ,* b! ace?ethnicit!' ,( b! >S adults and child en' (/.(2 %o#"le#enta ! #edicine de$inition' (3 elect onic " ocess o$ listin&' 11 %on&esti4e hea t $ailu e' natu al #edicines $o ' ,31 %onju&ated linoleic acid :%LA;' ,1( %onsolidated Standa ds o$ Re"o tin& T ials State#ent :%B8SBRT;' -/3' -/) %onsu#e Lab.co#' 0*' 0-' ()* dieta ! su""le#ent testin& in& edient:s; content' -(/ esults' -(1.-(2 sa#"le collection' -() histo !' -() Golunta ! %e ti$ication 9 o& a#' -(/ %ontinuin& Medical Education :%ME; cou ses' ()).()/ %o nsilk' ,(, %ouncil $o Res"onsible 8ut ition :%R8; dieta ! su""le#ent5 ele4ant la+s su""o ted b!' --,.--0 $unctions o$' --( and 8AD initiati4e in DS ad4e tisin&' --)' --/ objecti4es o$' --(.--, ele4ance to " actitione ' -(* as esou ce $o dieta ! su""le#ent esea ch' --/.--1 sel$5 e&ulation acti4ities' --) and SIDI " otocol' --/' --1 stakeholde education acti4ities' --1.--2 st ate&ic " inci"les o$' --, +ellness ca#"ai&n' -(* % a#" ba k' ,(-.,(( % anbe ! $o >TI " e4ention' -)2' ,(,' ,,(.,,,' ,2* Crataegus monogyna. See Ha+tho ne % eatine su""le#entation' ,3* %R8.8AD " o& a#' --/ %!stic acne' (/0 %!toch o#e 903* (D) :%C9(D); isoen<!#e de$icienc!' -01

D Da k chocolate' ,*2 DASH diet' ,*/ $o h!"e tension " e4ention' ,/( Deh!d oe"iand ostendione :DHEA;' --0 De" ession' natu al #edicines $o ' ,32.,)* De4ilHs cla+ $o #ulations' ,0$o lo+ back "ain " e4ention' ,-)' ,// $o osteoa th itis " e4ention' ,10 Diabetes diet and exe cise eco##endations' (2( nut itional su""le#entation $o al"ha5li"oic acid' (2*.(2-' ,)( A#e ican &insen&' ,)( blond "s!lliu#' ,)( coen<!#e =-*' (2* E9A and DHA' (12 #a&nesiu#' (12 eactions and inte actions o$' (2(.(2, eco##endations $o ' (2-.(2( so!' ,)( 4ita#in B-(' (2* 4ita#in D' (12.(2* "atient education li$est!le chan&es' (11.(12 esou ces' (20 "atient listenin& #edical histo !' (1/ "h!sical exa#ination' (11 t eat#ent and li$est!le histo !' (11 t eat#ent discussion and $ollo+5u"' (2, Diet and health' /,./0 Dieta ! Su""le#ent and 8on" esc i"tion D u& %onsu#e 9 otection Act :(**); ad4e se e4ent e"o tin&' )2./* $o consu#e " otection' 30.33 d u&s and dieta ! su""le#ent #anu$actu e s and' --0 Dieta ! su""le#ent :DS; use adolescent and !oun&5adult "o"ulation' 0) belie$s o$' 03 de#o& a"hics o$' 00 dieta ! "atte ns' 03 health status and beha4io o$' 03 li$est!le counselin&' 0/.01 "ediat ic "o"ulation' 0) "o"ulations +ith #edical dia&noses' 0).0/

Dieta ! Su""le#ent Health and Education Act :DSHEA; o$ -220' --, DS statuto ! de$inition in' ,0' 3*' )0' /, objecti4es o$' )0 @state#ents o$ nut itional su""o t'A // st uctu e?$unction clai#s o$ DS' //./1 Dieta ! su""le#ent indust ! challen&es associated +ith' -*0 sel$5 e&ulation' -*0' --) bene$its' -,-.-,( T uLabel " o& a#' -,(.-,, t ade associations. See T ade associations Dieta ! su""le#ent #anu$actu e s' es"onsibilities o$' --*.--$ietary Supplements% An Advertising Guide #or &ndustry, 1* Dieta ! su""le#ents :DS;' ,' (1 ad4e se e$$ects' -0ad4e se e4ent e"o tin&' )2./* beta5sitoste ol' (1(' (1, bioeDui4alence' -13 de$initions o$ $o ti$ied $oods' ,3.,) insu ance' ,3 le&al' ,3' 3*.3-' ((-.((( nono al intake' ,) e&ulato !' ,0.,3 education in health ca e t ainin&. See Health ca e t ainin&' dieta ! su""le#ent education in e$$icac! o$' -)3 health e$$ects' -2(.-2, labels desc i"ti4e na#e' ,1 intake eco##endations' ,2 state#ents allo+able on' ,/.,1' ), st uctu e?$unction clai#s. See St uctu e?$unction clai#s as li$est!le choice' / #ana&e#ent. See also 9h!sician' dieta ! su""le#ents discussion b! clinical tea# a"" oach' (*clinician and "atient a"" oach' (* he balist. See He balist natu o"athic "h!sicians :89s;. See 8atu o"athic "h!sicians :89s; nu ses. See 8u ses "ath+a!' (*.("ha #acist. See 9ha #acists e&iste ed dietitians :RDs;. See Re&iste ed dietitians :RDs; #oti4atin& $acto s $o ' ) natu al " oducts' ,* 8LEA health clai#s $o ' /3./) nono al $o #s' ,)

as "h!sician' (*1.(*2 "ost#a ketin& su 4eillance' ,/ " esc ibin&' 3* con$o #ance to labelin& e&ulations' -20 and inte action +ith d u&s' 3, kno+led&e o$ " actice &uidelines' 3(.3, license $o ' 3-.3( and " o$essional liabilit! insu ance' 3,.30 state la+ on' 3( ste"s $o ' 3).3/ "!&eu#' (1(.(10 Dualit! " oble#s +ith' -(/.-(1 e&ulation' )-' /* DSHEA o$ -220' )0' )) $ood la+s' )( 6T% Act' )) GM9 e&ulations. See Good Manu$actu in& 9 actices :GM9s; 8LEA o$ -22*' )3 nut ition labelin&' )3.)) and e&ulato s' -(2 state la+s' )) 4ita#ins and #ine als' )(.), esou ces on c ite ia $o ' (3(.(3, e4idence5based' (3( &o4e n#ent' (33.(3) handbooks' (3/' (32.()* he bal lite atu e' (3( #ono& a"hs' ()*.()9DA d u& in$o #ation' (3)' (3/.(32 thi d5"a t! testin&' ()* Eeb sites' (3,.(33 !e & ass "ollen ext act' (1,' (10 sa$et! o$' ((( sa+ "al#etto' (1(' (1, standa d o$ identit! $o ' ), thi d5"a t! e4aluation & ou"s' 0*' 0usa&e disclosu e and discussion +ith clinician' 3.) docu#entation' -*.->S #a kete s o$' /( Dieta ! Su""le#ents Labels Database' 0Dieta ! Su""le#ents Methods and Re$e ence Mate ials 9 o& a#' -2, D5Mannose $o >TI " e4ention' ,,, Docu#entation' -*.-Dolote$$in' ,0-

Dose5 es"onse cu 4e' -00 D u&.nut ient inte action database' --* D u&s ad4e se eactions' -0, de$inition' /, Du ban Botanic Ga dens' -)/ E Echinacea clinical t ial' -/1.-/2 $o cold and $lu " e4ention' -1*' ,3).,3/ 'chinacea purpurea. See Echinacea Ene &! the a"ies' (/ 'uropean Pharmacopoeia, 22 Eu4e&al $o te' ,/0 E4enin& " i# ose oil' ,0(.,0, E4idence5based 9 actice %ente s 9 o& a#' -20 E!e =' ,0( 6 6ati&ue' natu al #edicines $o ' ,),.,)0 6DAMA health clai#s' // 6DA Mode ni<ation Act o$ -22/' // 6DA5 e&ulated " oducts' cate&o ies o$ e&ulation $o ' --3 6ede al T ade %o##ission :6T%;' )) dieta ! su""le#ent ad4e tisin& case handlin&' --/ 6T% Act en$o ce#ent' 1* 6enu& eek' ,() 6e4e $e+' ,**' ,)/.,)1 6ibe ' health bene$its o$' /0 6ib o#!al&ia' natu al #edicines $o ' ,)3 6ish oils' ,0(' ,/1 $o blood " essu e eduction' ,*1 $o d!sli"ide#ia " e4ention' ,*1.,*2 $o h!"e tension " e4ention' ,/$o h!"e t i&l!ce ide#ia " e4ention' ,)2 $o obesit! " e4ention' ,1( and statins' (-6laxseed su""le#entation $o B9H " e4ention' (1$o #eno"ause " e4ention' ,1* 6olic acid' ,30 6ood Alle &en Labelin& and %onsu#e 9 otection Act o$ (**0' )( 6ood and D u& Ad#inist ation (6DA;' /( ad4e se e4ent e"o tin&' )2./* a"" oach to Duali$ied health clai#s' /).//

a"" o4al o$ health clai#s' /0./) dieta ! su""le#ents +eb "a&e' (33 noti$ication $o st uctu e?$unction clai# to' /1 e&ulations $o nut ition labelin&' )3.)) on substantiation o$ st uctu e?$unction clai#s' 1*.16ood' D u&' and %os#etic Act o$ -2,1 :6DI% Act;' )(' ), section (*-:$ ; o$' /( section (*-:&; o$' /, 6ood in& edient standa ds' -(( 6oods de$inition' /( $unctional' ,3.,) 8LEA health clai#s $o ' /3 $o s"ecial dieta ! use' ),' /(./, st uctu e?$unction clai#s $o ' /( vs. d u&s' /(./, G Galega o##icinalis. See GoatHs ue Ga lic $o h!"e tension " e4ention' ,/( inte action +ith d u&s' -3/ Gene ic d u&s' -13 Ge #an Medicines Act o$ -2/)' 20.2) Ge #an e&ulation o$ HM9s Ge #an #edicines act' 20.23 #a ketin&' 2) @"ost e&ist ationA " ocedu e' 23 Gin&e $o 8G9 " e4ention' ,(*.,($o osteoa th itis " e4ention' ,10 Gin(go biloba ad4e se eactions o$ sei<u e' -0/.-01 s"ontaneous bleedin&' -0/ $o &lauco#a t eat#ent' ,)) inte action +ith d u&s' -3/' -32 $o 8G9 t eat#ent' ,(*.,(Dualit! " oble# +ith' -(1 Glauco#a' natu al #edicines $o ' ,)) Glucosa#ine sul$ate :GS;' 3,' ,1, $o #ulations' ,0in knee e"lace#ent' (-GoatHs ue' ,() Goldenseal ext act' -11 Good Manu$actu in& 9 actices :GM9s;' ))' 2,

$o dieta ! su""le#ents' )/.)1' -*0.-*3 and DS Dualit! " oble#s' -(2.-,* 6DA5 e&ulated " oducts' --, G a<ax' ,00 G een tea ext acts' /) he"atotoxicit!' -01 G!no"lus' ,1* H Ha "adol' ,0Harpagophytum procumbens. See De4ilHs cla+ Ha+tho ne' ,31 Headache' natu al #edicines $o ' ,3*.,3Health ca e " actitione s access to a"" o4ed health clai#s' 0*' 0challen&es $aced b!' -*0 educatin&' ()3 kno+led&e o$ " actice &uidelines' 3(.3, and "ha #acist' (-)' (-1 T%M " actitione s' (00.(0) Health ca e t ainin&' dieta ! su""le#ent education in case stud!' ()0.()3 cle kshi" students' ()(.(), %ME test' ()).()/ inte& ati4e #edicine' (),.()0 issues associated +ith' ()/.()1 lea nin& o""o tunities' ()1 online lea nin&' ()/ textbooks' ()) Health clai#s de$inition' /3 6DA5a"" o4ed' /0./) 6DAMA' // Duali$ied' /).// substantiation o$' 1*.1He bal clinical t ial lite atu e' e4aluation o$ dosa&e $o #' -// dose5 an&in& studies' -/1 Echinacea " oducts' -/1.-1#ate ials and #ethods section' -/) "h!toche#ical contents' -//.-/1 "lant sou ce o$ inte 4ention' -/) " oduct e4aluation and standa di<ation' -//.-/1 taxono#ic in$o #ation' -/) He balis#' histo ! o$' (*(.(*0 He balist

de$initions' (*( Duali$ied #edical' (*3 oles and es"onsibilities as conse 4ationist' (*).(*/ in #edie4al e a' (*,.(*0 in " ehisto ! "e iod' (*(.(*, He bal #edicinal " oducts :HM9s; ad4e se eactions ca diac toxicit!' -0).-0/ causalit! assess#ent' -00.-03 clinical t ials and case e"o ts' -0) he"atotoxicit!' -0/' -01 #!o"ath!' -01.-02 e"o tin&' -02.-3sei<u e' -0/.-01 s"ontaneous bleedin&' -0/ t!"es o$' -0, +ith anti"latelet acti4it!' -)* Dualit! cont ol' 13 e&ulation in Aust alia. See Aust alian e&ulation o$ he bal #edicines e&ulation in %anada. See %anadian e&ulation o$ 8H9s e&ulation in Ge #an! Ge #an #edicines act' 20.23 #a ketin&' 2) @"ost e&ist ationA " ocedu e' 23 e&ulation in >nited Jin&do# Medicines Act o$ -2)1' 21.22 unlicensed he bal " oducts' 22 e&ulato ! cate&o ies $o ' 1, the a"eutic eDui4alenc! o$' -13 A9Is and "h!toeDui4alence' -1).-1/ bioa4ailabilit!' -1/ EHB su 4e! health5 elated clai#s' 13 #anu$actu in& e&ulations' 13.1) national "ha #aco"eia' 13 e&ulato ! cate&o ies o$ HM9s' 10.13 sa$et! assess#ent' 1) He bal #edicine labels needs $o ' ,1 $o tinctu es and standa di<ed ext acts' 0* H.E.R.B.A.L. #ne#onic co#"onents dieta ! su""le#ent discussion' -0.-3 docu#entation' -*.-lea nin& $o clinician' -).-/

"atient education. See 9atient education "atient listenin&. See 9atient listenin& eactions?inte actions' -(.-, de4elo"#ent' , and dieta ! su""le#ent counselin&' (*1.(*2 DS eco##endation' 3).3/ &oal o$' , eco##endation $o nu ses based on' (,* He b.d u& inte action associated +ith he bs A#e ican &insen&' -33 Bitte o an&e' -3) Black cohosh' -3) Ga lic' -3/ Gink&o' -3/ Ja4a' -31 Red !east ice' -31 So!' -31 St. KohnHs Eo t' -31 cate&o i<ation' -30.-33 incidence' -32.-)* #et$o #in' (,/ "ha #acokinetic?"ha #acod!na#ic' -33 "otential in elde l! "o"ulation' -30 atin&s' dist ibution o$' -30.-33 He bMed' (30 He bolo&!' (*( Hydrastis canadensis L' -11 H!"e choleste ole#ia dieta ! su""le#ents $o blond "s!lliu#' ,*/.,*1 DASH diet' ,*/ $ish oils' ,*1.,*2 Medite anean diet' ,*/ eco##endations o$' ,-* stanols' ,*1 4ita#in D' ,*2 "atient education DASH diet' ,*/ in$o #ation esou ce' ,--.,-( li$est!le #odi$ication' ,*) "atient listenin&' ,*3.,*) " e4alence' ,*3 t eat#ent discussion and $ollo+5u"' ,-H!"e li"ide#ia' natu al #edicines $o ' ,)2.,/* H!"e tension

dieta ! su""le#ents $o blond "s!lliu#' ,*/.,*1 cocoa' ,*2 DASH diet' ,*/ $ish oils' ,*1 Medite anean diet' ,*/ "otassiu# su""le#entation' ,*1 eco##endations o$' ,-* "atient education in$o #ation esou ce' ,--.,-( li$est!le #odi$ication' ,*) "atient listenin&' ,*3.,*) " e4alence' ,*3 t eat#ent discussion and $ollo+5u"' ,--