You are on page 1of 5

7

(supercritical state, SCS)1

(viscosity)

(surface tension)(diffusion

(supercritical fluid, SCF)

coefficient)

(1)

(Tc)

(Pc)

(critical temperature, Tc)(critical


pressure, Pc)(critical density,

c)

(critical point)

(g/cm 3 )

(g/cms)

(cm 2 /s)

10-3

10-4

10-1

10-2

10-5

0.2-0.9

10-4

10-3

S C F

Andrews1869

1879HannayHogarth

1937Michels

1950

(compressibility)(density)

(polar)(solubility)

(dielectric constant)

1970

1978

Bremen

2004623

CO 2

(supercritical carbondioxide,

SF-CO 2 )CO 2

72.8

(Pc72.8atm, Tc

31.1)

1.

(supercritical fluid

SF-CO 2

extraction, SCFE)

(mass transfer)

(extraction)(separation)

(cleaning)(coating)

(impregnation)(particle

(entrainer)

formation)(reaction)

(1)

31.1

atm

g/ml

CO 2

31.1

72.8

0.468

N 2 O

36.4

72.5

0.452
0.322

H 2 O

28.8

38.7

NH 3

132.5

112.8

0.235

CH 4 O

239.5

80.9

0.272

CH 4

-82.6

46

0.162

C 2 H 4

9.3

50.3

0.218

C 2 H 6

32.2

48.8

0.203

C 3 H 11

96.7

42.4

0.217

C 3 H 6

91.9

46.2

0.233

C 6 H 6

289.0

48.9

0.302

C 7 H 8

318.6

47.1

0.292

C 3 H 6 O

235.0

47.0

0.278

274.7

47.7

0.237

28.9

39.2

0.579

CH 3 CN

CF 3 Cl

10

) ( 1 0 9 )

(2)

(supercritical drying)

(rapid expansion of supercritical

solutions, RESS)

(particles from gas-saturated solutions,

1978

PGSS)(supercritical

Bremen

anti-solvent, SAS)

(solutions enhanced dispersion

by supercritical fluids,SEDS)

2.

3.

1990

4.

( 1 0 6

11

RaytheonCool Clean

5.

1995
199911
2003
1000

(Subcritical water

oxidation, SCWO)

1.
P154-P166112007
2.S u b r a m a n y a m B . , R a j e s w s k i R . a n d S n a v e l y K . ,
Pharmaceutical processing with Subcritical carbon dioxide, J.
Pharm. Sci., 86, 885~890(1997)