5.

Summary of the pathology curricular content

The candidate needs to have a good understanding of the general pathological processes which present to the Emergency Department or underpin nationally accepted guidelines. The majority have already been addressed in the Pathophysiology section. The remaining include: 5.1 Inflammatory response

Normal v Abnormal nflammatory mar!ers: "#P #heumatoid factors AN$

5.2 Immune response Normal Abnormal Hypersensitivity including anaphylaxis & anaphylactoid reactions

5.3 Infection %see also section 4, part b& The candidate should !now the typical causes' pathological processes and investigation of the following infections presenting to an ED: ( )pper respiratory tract

*ower respiratory tract + pneumonia ,eningitis + encephalitis ,yocarditis + endocarditis -epatitis .astro/enteritis )rinary tract infection 0TD PD "ellulitis

nfection of bones + joints A D0 P)1 ,alaria $ungal infection

5.4 Wound healing

.eneral principles 0pecific tissues: 0!in Tendon Peripheral nerve 2one ,yocardial 2rain

5.5 Haematology ( Anaemia 3 classification' causes' investigation *eu!aemia 3 classification4 acute and chronic lymphoblastic leu!aemia4 acute and chronic myeloid leu!aemia *ymphoma and myeloma "oagulation 3 platelet disorders' inherited and ac5uired coagulation disorder' thrombophilia