Membrane Models

Problem: proteins amphipathic 1972 Singer & Nicolson

Fluid Mosaic Model

Hydrophobic interactions
Movement of phospholipids and

proteins Fluidity maintained by unsaturated hydrocarbon chains & cholesterol Integral and peripheral proteins Carbohydrate chains

TRANSMEMBRANE PROTEIN

Plasma Membrane - sideness

Cytoplasmic face Extracellular face same composition as inside face of ER and vesicles Vesicle fusion enlarging the membrane Carbohydrate chains made in ER modified in Golgi

Membrane Protein Functions

Passive no energy required Down concentration gradient Molecule movements: independent & random Efficiency if gradient is steep, volume small, large surface area, high water potential Aided by cytoplasmic streaming & metabolic activities (subs. used as enter)

Facilitated Diffusion
Driven by concentration gradient (passive) Uses carrier proteins Ex. Glucose/insulin

MICROSCOPES CELL PART/FUNCTION CELL TRANSPORT MEMBRANE STRUCTURE

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