III – Implementation

1. Drug study

Name of drug Dose, Classification Mechanism of Indication of contraindication Side effects Nursing
dosage, action the drug responsibilities
route,
frequency

SPIRONOLACT PO 25- Electrolytic Steroidal For edema, • Contraindica CNS: • Check the
ONE 200mg/d in and Water compound hypertension ted in headache, blood
(aldoctone, divided balance and specific , patient drowsiness, pressure
novospriton) doses, agent; pharmacologi hypertensiv lethargy, before
continued for potassium- c antagonist e to drug confusion, initiation of
at least 5 d sparing for cellular ataxia therapy
( dose diuretic receptor sites GI: diarrhea, and at
adjusted to in distal renal • Contraindica gastric regular
optimal tubule. ted in those bleeding, intervals
response; if Promotes with anuria, ulceration, throughout
no response, sodium and acute or cramping, therapy
a thiazide or chloride progressive gastritis,
loop diuretic excretion renal vomiting • Assess for
may be without insufficiency GU: inability sign of fluid
added) concomitant , or to maintain and
loss of Hyperkalemi erection, electrolyte
potassium. a menstrual imbalance
Diuretic effect disturbance and signs
reportedly not • Use Hematologi of digoxin
associated cautiously in c: toxicity.
with patients agranulocyto
hyperuricemi with fluid or cis
a or Metabolic: • Observe for
electrolyte and report
hyperglycemi imbalance, hyponatremia
a. Activity , immediatel
impaired y the onset
depends on renal Hyperkalemia
the presence , dehydration, of mental
function, or changes,
of hepatic mild acidosis
endogenous disease Skin: lethargy, or
aldosterone. urticaria, stupor in
hirsutism, patients
• Use with maculopapul with liver
extreme ar eruption disease.
caution in Others:
pregnant gynecomastia • Adverse
women , breast reactions
soreness, are
drug fever, generally
anaphylaxis reversible
with
discontinua
tion of
drug.
Gynecomas
tia appears
to related
to dosage
level and
duration of
therapy; it
may persist
in some
after drug
is stopped.