Predisposing factors: *Age (5 to 30) *Gender (male :!

Precipitating factors: *Diet (Low Fiber)

" #ccl$sion of Appendi% b& Fecalit' " Decreased flow(drainage of m$cosal secetions " )ncreased )LP in t'e appendi% " *asocongestion " Decreased blood s$ppl& in t'e appendi% " Decreased # s$ppl& in t'e appendi% " Appendi% starts to be necrotic+ ,acteria in-ade t'e appendi% " Disr$ption of .ell /embrane of Appendi% " 0tart of )nflammator& Process " " " " 1elease of .'emical /ediators Acti-ation of t'e *omiting 2e$trop'ils to area .enter in t'e /ed$lla " " 3334 5istamine6 Prostaglandin6 0tim$lation of *ag$s 0$ppression of P$s Formation Le$7otrienes6 ,rad&7inin 2er-e 0&mpat'etic (p'agoc&ti8ed bacteria " G) F$nction and dead cells) 0welling of Appendi% 3334 Prostaglandin6 ,rad&7inin " 2a$sea 9 *omiting Anore%ia

Pain in t'e 1L: of Abdomen " Ac$te Pain 3334 )nterle$7in3! " )ncreased ;,. )nflammation of Appendi% (Appendicitis) " <

1$pt$red Appendi% (perforated) 0(s: 0welling of t'e abdomen 0e-ere pain ;eig't loss

Appendectom&

Peritonitis 0epsis 0eptic 0'oc7 .oma Deat' 0(s: Decrease blood press$re Decrease blood -ol$me