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S-budesonide Chemical Properties

S-budesonide is a glucocorticoid steroid for the treatment of asthma, COPD and non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. In addition, it is used for Crohn's disease (inflammatory bowel disease).

Name:S-budesonide EINECS:257-139-7 Molecular Formula:C25H34O6 CAS Registry Number:51333-22-3 Synonyms:Budesonide InChI:InChI=1/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28) 12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-, 20-,21?,22+,23-,24-,25+/m0/s1 HS Code:29372900 Appearance:white solid Molecular Weight:430.54 Density:1.27 g/cm3 Boiling Point:599.7 C at 760mmHg Melting Point:221-232 C (dec.)

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Flash Point:201.8 C Storage Temperature:Store at RT Refractive index:1.592 Solubility:Insoluble Biological Activity:Synthetic anti-inflammatory glucocorticoid that displays chemopreventive activity. Prevents formation of lung adenomas and adenocarcinomas in mice following inhalation or oral administration. Reverses DNA hypomethylation and modulates expression of cancer related genes. Stability:Stable at normal temperatures and pressures. Usage:A non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent