Landsteiner and weiner in the year 1940 discovered Rh.

The individual having the antigen is called Rhpositive and in whom it is not present, is called Rh- negative.

INCIDENCE : The incidence of Rh negative in Europe and American whites 15-17% China 1% Japan nil India- 5-10% (south india-5%, north india10%) Rh negative women has the chance of having a Rh positive fetus is 60% irrespective of the fathers genotype.

Hydrops fetalis. Icterus gravis neonatorum

Congenital anaemia of the newborn:

PREVENTION OF Rh- IMMUNISATION To prevent active immunization To prevent or minimize feto-maternal bleed To avoid mismatched transfusion