Generic Name Indication Mechanism of Action Contraindication Nursing

Consideration

Cefuroxime Prevent infection that Inhibits bacterial cell Contraindicated in >obtain specimen for
will occur because of wall synthesis, thus patient culture & sensitivity
difficulty to urinate promoting osmotic hypersensitivity to test before giving first
Brand Name: instability which drug or other dose.
eventually leads to cephlosporins.
Zinacef bacterial cell death >Assess patient for
allergic reaction and
Classification: anaphylaxis.

Cephalosporin >check for signs &

symptoms of a
Dosage: superinfections,
especially if client
750mg IV every 8hrs takes high doses of
Adverse Effect: cephalosporin for
prolonged period.
Nausea & vomiting,
headache, dizziness, >monitor vital signs,
loose stools, itching urine output,
laboratory results,
report abnormal
findings
Generic Name Indication Mechanism of Action Contraindication Nursing
Consideration

Metoclopromide GI motility Dopamine Antagonist GI hemorrhage >Inject slowly IV

disturbances that acts by increasing epilepsy, obstruction every 1-2 minute to
sensitivity to or perforation prevent transient
Brand Name: Nausea & vomiting of acetylcholine; results feelings of anxiety &
central & peripheral in increased motility of restlessness
Placil origin associated with the upper GI tract and
infectious diseases & relaxation of the >N&V, anorexia,
Classification: drug induced. pyloric sphincter & constipation
duodenal bulb. abdominal distention
Anti emetic before 7 after
administration.
Dosage:
Adverse Effect: >Report lack of
1 amp IV every 8 response , persistent
hours Restlessness, side effect so that they
drowsiness, fatigue, can be properly
dizziness, nausea, evaluated.
headache.
>Frequent monitor BP
of pt’s taking IV form
of drug

>Assess pt’s GI
complaints
Generic Name Indication Mechanism of Action Contraindication Nursing
Consideration

Ambroxol HCL Acute & chronic May increase the Hypersensitivity >Assess cough, type
disorders of output of fluid from the Gastric Ulceration frequency character
respiratory tract respiratory tract by including sputum
Brand Name: associated with reducing the viscosity
bronchial secretions & surface tension of >Provide adequate
Mucosolvan respiratory secretions, hydration to 2 L/day to
thereby removing decrease viscosity of
Classification: accumulated secretions.
secretions from upper
Expextorants & lower airway. >Monitor for possible
adverse reaction
Dosage:
>Suggest sugarless
750 mg/cap once a Adverse Effect: lozenges to decrease
day throat irritation &
Headache, cough hard candy can
tachycardia, fatigue, be used to prevent dry
N&V GI discomfort. mouth
Generic Name Indication Mechanism of Action Contraindication Nursing
Consideration

Domperidone Dyspeptic Symptom Selectively blocks GI hemorrhage >Assess for GI

complex associated peripheral dopamine mechanical complaints, before &
with delayed gastric receptors in the GI obstruction of after administration
Brand Name: emptying. wall and in the perforation. Pt with
chemoreceptor trigger epilepsy >Assess for change in
Andlogan Symptomatic relief of zone thus enhancing bowel habits
N&V normal synchronized
Classification: GI peristalsis & >Inform the pt to take
motility in the proximal the medication before
Anti flatulents region of GIT meals. If taken after
counteract anti- meals absorption is
Dosage: cholinergic induced somewhat delayed.
relaxation of lower
10 mg 1 tab TID esophageal sphincter. Adverse Effect: >Instruct the pt to
inform physician if
Intestinal cramps, transient intestinal
drowsiness, lashes & cramps occur.
other allergic reaction.
Generic Name Indication Mechanism of Action Contraindication Nursing
Consideration

Hyoscine-N-butyl Various painful Inhibits acetylcholine Glaucoma megacolon, >Give by direct IV

bromide condition GI spam at receptor sites in hypersensitivity, after diluting with
irritable colon, biliary autonomic nervous paralytic ileus, sterilize water
colic, urinary colic system, which controls tachycardia
Brand Name: secretions, free acids >Monitor I&O ratio,
in stomach. retention commonly
Buscopan causes decreased
urinary output
Classification:
>Assess for
Anti spasmodic constipation

Dosage: >Assess for tolerance

Adverse Effect: over long term therapy
1 amp every 8 hours
Dry mouth, dizziness,
fatigue, rash anorexia,
headache