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ABGs CSF
PH 7.35~7.45 Protein 10~40mg/dl
PaCO2 35~45mmHg Glucose 40~80mg/dl
PaO2 75~100mmHg (0.6 x Serum glucose)
HCO3 22~26mEq/l Pressure 80~180mmH2O
SaO2 95~98% Leukocyte,total <5/HPF
SvO2 60~85% Leucocyte,Diff
BE 0±2mmol/l Lymph 60~75%(70%)
tCO2 23~27mmol/l Mono 25~50%(30%)
pH= 6.1+log([HCO3-]/0.03PaCO2) Neutro 1~3%
[H+](nM/L)= 24x(PaCO2/[HCO3-]) Cell Count 0~5lymphs/HPF
PAO2= (Patm-PH2O)×FIO2-PaCO2/R Osmolarity 292~297mOsm/L
A-aDO2= PAO2-PaO2(room air<10~12) Albumin(serum) 3800~5300mg/dl
CaO2= 0.003×PaO2+1.36×Hb×SaO2 Lactate <2
AG=[Na+]-([HCO3-]+[Cl-]);12±4mEq/L IgG(serum) 917.2~1891.2
IgG index <0.7(0.65)
Metabolic acidosis IgG index
HCO3- deficit(mEq/L)= = IgG(CSF)/IgG(serum)
[0.5xbody weight(kg)]x(24-[HCO3-]) Albumin(CSF)/Albumin(serum)
Expected PaCO2= 1.5x[HCO3-]+8±2
Others
Metabolic alkalosis Apo B M: 96~176 , F: 42~112 mg/dl
HCO3- excess(mEq/L)= Apo A M: 96~176, F: 109~203 mg/dl
[0.4xbody weight(kg)]x([HCO3-]-24) ASLO Adult:<200, Child:<100 T.U/ml
Expected PaCO2 ([HCO3-]≦40mEq/l) α1-Antitrypsin 144.6~151.4mg/dl
= 0.7x[HCO3-]+21±1.5 α1-acid glycoprotein 33~88mg/dl
Expected PaCO2 ([HCO3-]>40mEq/l) α2-macroglobulin 120~269mg/dl
= 0.75x[HCO3-]+19±7.5 β2-microglobulin
Blood:70~340μg/dl
Respiratory acidosis Other:<12.6μg/dl
Acute △pH/△PaCO2 = 0.008 Ceruloplasmin 21~53mg/dl
Chronic △pH/△PaCO2 = 0.003 Microalbumin (urine) <1.9mg/dl
Prealbumin 17.0~42.0mg/dl
Respiratory alkalosis RA factor(RHF) <30IU/ml
Acute △pH/△PaCO2=0.008 Transferrin 299.5~316.3mg/dl
Chronic △pH/△PaCO2=0.002
Tumor marker
AFP <25ng/ml
Others CEA <2.5ng/ml
Vitamin B12 200~950pg/ml CEA,Smoker <5.0ng/ml
Folate 3.0~17.0μg/ml Ca-15-3 <30U/ML
Aluminum 4~10ug/l CA-19-9 <37 U/ml
Copper 90~200ug/dl CA-125 <30U/ml
Zinc 50~150ug/dl Free β-HCG 0~10mIU/ml
TPA <70 U/L
SCC ≦1.5 ng/ml
PSA 0~4ng/ml
Drug level
Digoxin 1~2μg/l Gentamicin
Trough:<2μg/ml
Lithium 0.5~1mmol/l Peak:
Phenobarbital 10~40mg/l Traditional dosing
Tegretol(CBZ) 5~10mg/l 5~12μg/ml
Phenytoin(DPH) 10~20mg/l Extended-interval dosing
Valproic acid 50~100mg/l 10~20μg/ml(<65y/o)
Theophylline 10~20mg/l 10~18μg/ml(>65y/o)
Amikacin Vancomycin
Trough: 1~8μg/ml Trough:5~15μg/ml
Peak: 20~30μg/ml Peak:20~40μg/ml
Ethanol <3mmol/l
Lab Value Transudate Exudate
Specific gravity <1.016 >1.016
Absolute protein <3g/dL >3g/dL
Protein(ascitic or pleural to serum <0.5 >0.5
ratio)
LDH(ascitic or pleural to serum <0.6 >0.6
ratio)
Absolute LDH <200IU >200IU
Glucose <1 >1
+(serum to ascitic or pleural ratio)
Fibrinogen(clot) No Yes
3
WBC(ascitic) <500/mm >1000/mm3
WBC(pleural) Very low >2500/mm3
Differential(pleural) PMN early, monocytes later
RBC(ascitic) >100 RBC/mm3
pH(pleural):一般>7.3,
在 7.2 和 7.3 之間:考慮 TB 或 malignancy 或兩者。 若<7.2:考慮 empyema
Glucose(pleural):normal pleural fluid glucose=2/3serum glucose,
RA 可能會低到 0~16mg/dl
TG(>110mg/dl) 和 Sudan stain(+)(pleural fluid):chylothorax
Food fibers(ascitic):perforated viscus
CSF study 壓力 細胞數 主要的細 糖份 蛋白質
(mmH2O) / mm3 胞種類 (sugar) (protein)
正常 60~200 0~5 L 50~100mg/dl 20~45
(80~180) mg/dl
急性細菌性腦膜炎 上升 1000~5000 PMN 下降 上升
結核菌性腦膜炎 上升 50~500 L 下降 上升
黴菌性腦膜炎 正常 or 100~700 PMN,L,M 下降 正常 or
(如隱球菌) 上升 上升
腫瘤引起之腦膜炎 * 0~500 PMN,L,M 正常 or 下降 *
疱疹性腦炎 * 50~100 L,M 正常 正常
無菌性腦炎 aseptic * 10~1000 L 正常 *
急性梅毒性腦膜炎 * 25~2000 L 正常 上升
急性發炎性脫髓鞘 正常 0~5 L N 上升
病變