Mansergh and Cosette Seidenberg Current Topics Presentation: Young Scientist in the News Connor Hearn Background
Lives in Vancouver, Canada
14 year old scientist
Researches at his own home
Has always been interested in science since an early age Background In 2 nd grade, Hearn was already beyond his peers and even teachers
When being taught about liquids, solids, and gases, Hearn asked his teacher: What about plasma and Bose-Einsten condensate? News: Hearns Article Hearn published article on Ebola virus
A Brief Passage of Time in the Deadly Ebola Virus
Using computer graphics, made models
Took 3 weeks to write the article; many more weeks had been previously dedicated to the research itself
Would like to know how exactly he went about doing his research Publicity Hearns article published April 16, 2014
Interest in virus piqued while researching for Tekmira Pharmaceuticals
After Ebola epidemic in West Africa, Hearns article received massive publicity
Viewed in more than 130 countries Recognition Praise from around the world, featured on Global News on September 8 th
Professor from the University of Illinois reached out to Hearn, asking for a PowerPoint
clearest descriptions of the Ebola viruss replication he had ever seen (Global News) Hearns Research Hearns research included details on: When the virus started How it duplicates How it spreads The basic cause of Ebola What the virus looks like Hearns Ebola Research 4 versions of Ebola: Sudan, Bundibugyo, Tai forest, and Ebola viruses
Fifth version, Reston virus, does not affect humans
Thread-like structure
Filovirus Tubular virons, diameter of approx. 80 nanometers
Made of single-strand RNA wound helically with the proteins NP, VP35, VP30, and L
Reproduces in host cell
Attaches itself by activating glycoproteins, which create 10 nanometer spikes
Ebola is a host cell virus, like HIV
Ebola needs cholesterol transporter Niemann- Pick C1 (NPC1) in order to enter cells
Once inside: virus fuses with the vesicle membrane, and is released into the host cells cytoplasm
Addresses the recent Ebola outbreak, educates society about the virus
Important because its killed thousands already, and several Americans have contracted the disease as well Hearns Article: Graphics Credits Global News globalnews.ca/news/1549422/young- scientist-garnering-international- attention-for-ebola-research/ A Brief Passage of Time in the Deadly Ebola Virus connorhearn.com/the-deadly-ebola- virus/