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#*  680312    (Pathophysiology)


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Function and homeostasis mechanisms of various organ systems in pathological states,
including cell abnormalities, neuro-muscular, cardiovascular, respiratory, gastrointestinal, renal,
endocrine and reproductive systems. Emphasized integrative compensation of associated
systems in pathological state. Clinical signs and symptoms related to organ malfunction.
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Unit 1: Disorders of endocrine function (7)
- Pituitary and growth disorders
- Thyroid disorder
- Disorders of adrenal function
- Diabetes mellitus & metabolic syndrome
Case study: Diabetes mellitus & metabolic
syndrome
Unit 2: Disorders of reproductive function
(2)
- Menstrual disorder
- Infertility
- Gestational disorder
Case study: Menstrual disorder
Unit 3: Disorders of renal function (4)
- Disorders of glomerular function
- Tubulointestinal disorders
- Renal failure
Case study: Renal failure
Unit 4: Alterations in fluids & electrolytes (2)
- Alterations in fluid volume
- Alterations in sodium, potassium & calcium
balance

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Case study: Fluids & electrolytes imbalance


6
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10
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6 -  

Unit 5:Disorders of cell growth & function (3)


- Cellular adaptation, cell injury & dead
- Necrosis & apoptosis
- Inflammatory response
- Tissue repair and wound healing
Case study: Inflammatory disease
Unit 6:Disorders of neuromuscular function
(8)
- Upper motor neuron diseases
- Lower motor neuron diseases
- Cerebellar lesions
Case study: Cerebrovascular diseases and
Myasthenia gravis

=> 7?

 " : Unit 1 - 5


3

11
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- Basal ganglia lesions


Case study: Parkinson)disease
- Disorder of sensory system
- Spinal cord injury
- Mechanisms of pain
Case study: Migraine headache
- Degenerative disorders
- Brain dysfunction
- Seizure disorders
Case study: Alzheimer)s disease
Unit 7: Disorders of gastrointestinal function
(4)
- Disorders of motility
- Disorders of secretion
- Disorders of digestion and absorption
- Disorders of hepatobiliary function
Case study: Gastroesophageal reflux disease
Unit 8: Blood disorders (4)
- Red blood cell disorders
- White blood cell disorders

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2.

  -

- Disorders of hemostasis
Case study: Blood disorders
Unit 9: Disorders of cardiovascular function
(7)
- Disorders of cardiac function
- Disorders of blood pressure regulation
- Disorders of blood flow in systemic circulation
- Heart failure
- Circulatory shock
- Case study: Heart failure
Unit 10: Disorders of respiratory function
(4)
- Disorders of lung inflation
- Obstructive airway disorders
- Pulmonary vascular disorders
- Obstructive airway disorders
- Pulmonary vascular disorders
- Pulmonary edema and respiratory failure
Case study: Lung diseases

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%&*-
1) McPhee SJ., Lingappa VR., & Ganong WF. Pathophysiology of Disease: An
Introduction to Clinical Medicine. 6th ed., McGraw-Hill, NewYork, 2010.
2) Porth CM. Pathophysiology : Concepts of Altered Health States. 8th ed., Lippincott
Williams & Wilkins, Philadelphia, 2010.
3) Silbernagl S., Lang F. Color Atlas of Pathophysiology. 2nd ed., Thieme, NewYork, 2000.
4) Curtis L. Atlas of Pathophysiology. 3rd ed., Lippincott Williams & Wilkins, NewYork,
2009.
 . Website .H,-# % %C  
1) Free MIT Open Course Ware: http://ocw.mit.edu/index.htm
2) E-learning J37 
: http://ncourse.buu.ac.th
3) Free data base of medicine: http://accessmedicine.com/features.aspx
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 2
% (Test Blueprint)

1. Unit 1: Disorders of
endocrine function
2. Unit 2: Disorders of
reproductive function
3. Unit 3: Disorders of renal
function
4. Unit 4: Alterations in
fluids and electrolytes
5. Unit 5: Disorders of cell
growth and function
6. Unit 6: Disorders of
neuromuscular function
7. Unit 7: Disorders of
respiratory function
8. Unit 8: Blood disorders
9. Unit 9: Disorders of
cardiovascular function
10. Unit 10: Disorders of
gastrointestinal function
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