Vet Pathol 41:4, 2004

Book Reviews

453

ganization, and Infectious Cycles and (B) Pathogenesis

Snapshots (Diseases, Epidemiology, and Disease Mechanisms of Selected Animal Viruses [in human beings], etc).
For the student of basic virology or for the instructor of
veterinary virology, this text is invaluable and could be enhanced if a CD of illustrations accompanied the text. For the
pathogenesist this text provides a clear and updated compendium of replication. However, mechanisms of pathogenesis applicable to veterinary diseases and problems are given
little attention. Indeed, this text on animal viruses largely
fails to address the viruses of animals. The text is a must
have for virology instructors and in any research or teaching library; its utility on the shelf of a pathologist will be
more limited.
Dr. K. E. Nusbaum
Department of Pathobiology
College of Veterinary Virology
Auburn University, AL

Flint, S. J., Enquist, L. W., Racaniello, V. R., and Skalka, A.

M. Principles of Virology: Molecular Biology, Pathogenesis,
and Control of Animal Viruses, 2nd ed. 944 pp. ASM Press,
Washington, DC, 2004. $109.95. ISBN 1-55581-259-7.
The second edition of Principles of Virology is divided
into four major units: The Science of Virology, a brief introduction (61 pp.); Molecular Biology, which takes up half
the book (426 pp.); Pathogenesis (205 pp.), with a large section on human immunodeficiency virus (30 pp.); and Control
and Evolution (99 pp.). Obviously, the emphasis of the book
is on viral replication, and it is wonderfully successful in
treating this aspect of virology. This is the most visually
attractive virology book ever published, and the effort invested in illustrating replication gratifies the reader. The numerous illustrations are detailed and highly colored and are
sequenced so that the reader can easily follow transitions and
progress of replication. Photographs of histology, immunofluorescence, and electron micrographs are all superb. The
writing style is direct and free of jargon; new terms are introduced in bold type and are further explained in an extensive glossary or in one of the numerous colored boxes that
cover background, clarification of terms, explanations of details and specific experiments, and health policy statements.
Two excellent appendices cover (A) Structure, Genome Or-

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