Non Mendelian Genetics:

Sex-Linked Traits

Lecture Notes

Karyotype: A photograph of a cells chromosomes arranged in ___________ according

to size
Normal Karyotype: _______________ pairs of chromosomes
Sex-Linked Traits:

Those traits whose genes are found on the X chromosome but ________ on the
Y chromosome

Examples of Sex-linked Traits:

Red-green colorblindness
Male Pattern Baldness
Hemophilia (Queen Victoria was a carrier)
Duchene Muscular Dystrophy (fatal)

Sex-Linked Traits

Gene is attached to the X chromosome only, not found on the Y chromosome

at all.
Women have XX, men have XY chromosomes
These disorders are more common in boys
examples: red-green colorblindness

Sex-Linked Traits

In males, there is no second X chromosome to _______________ a recessive

gene.
If _____________ get an X with the disorder, they have it.
_______________ must inherit defective Xs from _______________ parents.

What is the number inside of each circle?___________, ____________,

____________,____________
Example of Sex-Linked Trait

H = Normal blood clotting

h = Hemophilia

Example of Sex-Linked Trait

Normal male:_______________________
Male with Hemophilia:______________________
Normal female (not a carrier for hemophilia homozygous):__________________
Normal female (carrier for hemophilia heterozygous): _____________________
Female with Hemophilia: __________________________

Sample Problems
1. XHXh

x XHY

Chances of:

Punnett Square

a. hemophiliac child?
b. hemophiliac son?
c. hemophiliac daughter?
d. daughter who is carrier?

2. A woman who is a carrier for hemophilia marries a hemophiliac man.

Chances of:

Punnett Square

a. hemophiliac child?
b. hemophiliac son?
c. hemophiliac daughter?

3. A normal man marries a Homozygous normal woman.

Chances of:
a. Will any of their kids be

Punnett Square
hemophiliacs?

4. A normal woman (whose father is a hemophiliac) marries a hemophiliac man.

What are their genotypes?