Initials of patient: R.

A
Age: 48 years old
Sex: M
DRUG
Generic Name:
Ceftriaxone
Brand Name:
Omnicef
Classification:
Antibiotic
Dosage:
300 mg
Route:
Oral
Frequency:
OD
Form:
capsule
Color:
Blue

Date of Admission:
Diagnosis: Cerebral Malaria
Date medication started:
MECHANISM OF
ACTION
Works by inhibiting
the
mucopeptide
synthesis
in
the
bacterial cell wall. The
beta-lactam moiety of
Ceftriaxone binds to
carboxypeptidases,
endopeptidases,
and
transpeptidases in the
bacterial cytoplasmic
membrane.
These
enzymes are involved
in cell-wall synthesis
and cell division. By
binding
to
these
enzymes, Ceftriaxone
results in the formation
of of defective cell
walls and cell death

INDICATION
-

UTI;
lower
respiratory tract,
bone or joint, intraabdominal, skin, or
skin
structure
infection;
septicaemia

CONTRAINDICATION
-

Contraindicated
in
patients hypertensive to
drug
or
other
cephalosporins

ADVERSE/SIDE
EFFECTS

NURSING
RESPONSIBILITIES

Side effects:
GI: diarrhea
Hematologic:
eosinophilia,
thrombocytosis
Skin:
pain,
induration,
tenderness
at
injection site, rash
Other:
hypersensitivity
reactions, serum
sickness

Pre-administration
Check
doctors
order

Adverse effect:
GI:
psuedomembranou
s colitis
Hematologic:
Leukopenia
Other:
anaphylaxis

Observe 10 Rs

Obtain specimens
for culture and
sensitivity
before
initiating therapy.

Intra-administtration
Hold medication if
there is anaphylaxis
or allergic reactions
Post administration:
Document
Observe
for
adverse reactions