Chronic glomerulonephritis

GROSS
EXAMINATION

The kidneys are small and

contracted weighing as low as 50
gm each.
The capsule is adherent to the
cortex and the cortical surface is
generally diffusely granular.
On cut section, the cortex is narrow
and atrophic while the medulla is
unremarkable

MICROSCOPIC
EXAMINATION

Glomeruli are reduced in number and most of them show

completely hyalinised tufts appearing as acellular
eosinophilic masses.
Many tubules completely disappear, atrophy of tubules close
to scarred glomeruli and tubular lumina contain eosinophilic
homogeneous casts.
There is fine delicate fibrosis of the interstitial tissue and
varying number of chronic inflammatory cells in the
interstitium.