20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.

209

allergic rhinitis, AR

2012 8 2013 11 42 AR

2 21 1 4
3 4 2
1 4 total nasal symptoms score, TNSStotal non-nasal
symptom score, TNNSSrhinoconjunctivitis quality of life
questionnaire, RQLQ

1 TNSSTNNSS RQLQ

[5.04.06.0 9.07.010.01.01.01.5 3.03.03.044.035.5

50.0 60.053.575.06.05.58.0 10.08.510.12.02.03.0
3.003.03.050.045.558.0 43.027.048.0]
P 0.01
2 TNSSTNNSS RQLQ P 0.01
4
TNSS[2.01.03.0 3.02.04.5]TNNSS[1.00.01.0 2.02.03.0]
RQLQ[24.019.029.0 43.027.048.5]P 0.01

AR

Acupuncture at the sphenopalatine ganglion for the treatment of patients with

moderate-to-severe allergic rhinitis Chen Luquan*, Wang Kuiji, Tan Yi, Zhang Yanchao, Yang Wei,
Li Xinwu, Fang Gaoli, Wang Chengxiang.

Department of Acupuncture, Beijing Tongren Hospital, Capital

Medical University, Beijing 100730, China

Corresponding author: Wang Chengxiang, Department of Respiratory Medicine, Beijing Dongzhimen Hospital,
Beijing University of Chinese Medicine, Beijing 100700, China; Email: wang601@sina.vip.com
Abstract

Objective

To assess the clinical efficacy of acupuncture at the sphenopalatine ganglion

for the treatment of patients with moderate to severe allergic rhinitis. Methods 42 cases of moderate to severe
allergic rhinitis patients in Otorhinolaryngology clinic of Tongren Hospital between August 2012 to November
2013 were randomized into a treatment group and a control group. The treatment group was treated by
acupuncturing sphenopalatine ganglion, once per week, altogether 4 times. The control group was treated by
acupuncturing Fengchi (GB20), Baihui (GV20), Yingxiang (GV29), Shangxing (GV23),Taiyang (EX-HN5),
Quchi (LI11) and Zusanli (ST36) was used in the control group, 3 times per week for 4 weeks. The changes of
the Total Nasal Symptoms Score (TNSS) and the Total Non-Nasal Symptom Score (TNNSS) were evaluated
before and after treatment. The Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) was used to evaluate
DOI: 10.3760/cma.j.issn.1673-4246.2015.03.005
2014BBYJ01
JJ2013-26

TRYY-KYJJ-2014-037
100730

100011 100070

Email: wang601@sina.vip.com

210 20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.3
the quality of life. Results One week after treatment, the scores of TNSS, TNNSS and RQLQ in both groups
were significantly improved than before the treatment (treatment group: 5.0[4.0, 6.0] vs. 9.0[7.0, 10.0],
1.0[1.0, 1.5] vs. 3.0[3.0, 3.0], 44.0[35.5, 50.0] vs. 60.0[53.575.0]; control group: 6.0[5.5, 8.0] vs. 10.0[8.5,
10.1], 2.0[2.0, 3.0] vs. 3.00[3.0, 3.0], 50.0[45.5, 58.0] vs. 43.0[27.0, 48.0]; all P<0.01); the scores of TNSS,
TNNSS and RQLQ 1 week after treatment in the treatment group were significantly improved than those in the
control group. The scores of TNSS (2.0[1.0, 3.0] vs. 3.0[2.0, 4.5]), TNNSS (1.0[0.0, 1.0] vs. 2.0[2.0, 3.0])
and RQLQ (24.0[19.0, 29.0] vs. 43.0[27.0, 48.5]) 4 week after treatment in the treatment group were
significantly improved than those in the control group (all P<0.01). Conclusions Acupuncture at the sphenopalatine
ganglion could relieve the symptoms and improve the quality of life in patients with moderate to severe allergic
rhinitis, and show more rapid and persistent therapeutic effect. It may be superior to the common acupuncture.
Key words Rhinitis, allergic; Acupuncture; Ganglia, parasympathetic; Quality of life; Treatment outcome

allergic rhinitis, AR

23 12 11

51.014.0 22

[1]

12 10 48.810.5

[2]

2011

P 1.0000.176

1.2

AR

0.35 mm 60 mm2

1
1.1

2012 8 2013 11

45

55 mm

[3]

1385

4 4

15 5

1
total nasal symptoms

[4]

[ ]

score, TNSS 4 1860

23

2 min

24 h

24 h

1 4

45 AR

0.30 mm

40 mm 25 mm

2 1 42

25 mm

[ ]

20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.3

211

13 mm

MQ1Q3 8 P0.05

[ ]

20 min 1
3 4 12
1.3

TNSS

2 45 3

5 0 1 2

3 4

2.1 2

TNSS total

non-nasal symptom score, TNNSS

2 TNSSTNNSSRQLQ

P0.01
1 4

0 1

P0.01
1

[7 ]

TNNSS

2.2

rhinoconjunctivitis quality of

24 h

life questionnaire, RQLQ

24 h 3 d

7 24 0
1 2 3
4 5

AR

RQLQ 2 1

4 1

AR

1.4

SPSS 13.0

x s

2 TNSSTNNSSRQLQ [M(Q1Q3)]

TNSS

23

9.0(7.0,10.0)

3.0(3.0,3.0)

60.0(53.5,75.0)

21

5.0(4.0, 6.0)a

1.0(1.0,1.5)a

44.0(35.5,50.0)a

21

2.0(3.0, 1.0)ab

1.0(1.0,0.0)ab

24.0(29.0,19.0)ab

TNNSS

RQLQ

22

10.0(8.5,10.1)

3.0(3.0,3.0)

43.0(27.0,48.0)

21

6.0(5.5, 8.0)a

2.0(2.0,3.0)a

50.0(45.5,58.0)a

21

3.0(2.0, 4.5)a

2.0(2.0,3.0)a

43.0(27.0,48.5)a

TNSSTNNSSRQLQaP0.01
bP0.01

212 20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.3

1 4

3 20 min

9
[ ]

10

Allergy,2008,63(86):8-160.
4

guidelines[J]. Allergy,2007,62(4):367-372.

,,.
[J]. ,1995,12(1):6-8.
. [J].
,2009,25(1):1-3.

4 1

Bousquet J,Combesure C,Neukirch F,et al. Visualanalog scales

can assess the severity of rhinitis graded according to ARIA

Bousquet J,Khaltaev N,Cruz AA,et al. Allergic Rhinitis and its

World Health Organization,GA(2)LEN and Allergen)[J].

,.

Impact on Asthma(ARIA)2008 update(in collaboration with the

Skoner DP. Allergic rhinitis:definition,epidemiology,path-

[J]. ,2012,31(8):631-633.

[11]

2001,108(Suppl 1):S2-S8.
2

ophysiologu,detection,and diagnose[J]. J Allergy Clin Immunol,

Juniper EF. Measuring health-related quality of life in

rhinitis[J]. J Allergy Clin Immunol,1997,99(2):S742-S749.

,.
[J]. ,2005,13(5):397-399.

,.
[J]. ,1997,32(3):163-166.

10 . 3
[J].
,2011,25(5):193-196.
11 ,,,. 3

[J]. ,2013,35(7):

586-589.

2014-10-16