Drug Study

Generic Name: acetaminophen Trade Name: Abenol, Acephen, Acet, APAP, Artritol, Aspirin Free Anacin, Atasol, Cetafen, Feverall, Fortolin, Infantaire, Little
Fevers, Mapap, Nortemp Childrens, Ofirmev, Pain-Eze, Pediaphen, Pediatrix, Silapap, Silapap Infants, Taminol ,Tempra, Tylenol, Valorin
Classification
antipyretics,
nonopioid
analgesics

Mechanisms
of Action
Inhibits the
synthesis of
prostaglandi
ns that may
serve as
mediators of
pain and
fever,
primarily in
the CNS.
Has no
significant
antiinflammator
y properties
or GI
toxicity

Pharmacoki
netics
Absorption:
Well
absorbed
following
oral
administrati
on. Rectal
absorption is
variable. IV
administrati
on results in
complete
bioavailabili
ty
Distribtution
: Widely
distributed.
Crosses the
placenta;
enters breast
milk in low
concentratio
ns
Metabolism
and
Excretion:
85-95%
metabolized
in the liver.
mETABOLI
TES MAY
BE TOXI

Indications/Uses

Side Effects

Dosage and Routes of

Administration

Antidote

Nursing Implications