Name:

________________________
Date: ___________________

Period: ________

Changes in DNA Worksheet

Word bank: Mutation
Single
Chromosomal
Chromosomes
Substitution





Insertion
Deletion
Inversion
Duplication

1. In __________________, a section of a chromosome changes its position.

2. A _________________ is a change to the structure or organization of DNA.

3. In ____________________, a base pair is added to a gene.

4. A gene mutation is mutation to a ____________ gene.

5. A ______________________ mutation is a change to the structure or organization of a chromosome.

6. In _________________, a section of a chromosome is deleted.

7. DNA winds very tightly to form chromatin, which forms ______________________.

8. In __________________________, one base pair is replaced with another base pair in a gene.

9. In __________________, a section of a chromosome changes its position.

10. In ________________, a base pair is removed from a gene.

For each of the following, determine 1. What type of mutation has occurred, 2. Does this mutation
change the amino acid sequence? You will need to come up with a complimentary strand of mRNA
to determine the amino acid sequence. Remember: A-U; G-C.

Original


Mutation
AATGCCATG

AAATGCCATG



1.

2.


Original


Mutation
GCGATACGC

CCGATACGC


1.

2.




Original


Mutation
GGGAAATTT

GGGAAATT


1.

2.

Original


Mutation
AAATTTGGG

AAAATTTTTGGGG


1.

2.

The following letters represent sets of genes in a chromosome that has mutated. For each of the
following, identify what mutation has occurred.

Original



E
F
G
I
J
H



Mutation:




E
I
G
F
J
H



Mutation:




J
E
F
G
I
J
H



Mutation:




F
G
I
J
H

 Mutation:



H