Why Chronic Inflammation is really the

Proven Cause of Illnesses?

Inflammation is an innate biological process that, like stress, is good for

you in small amounts and detrimental if it becomes chronic. Typical
healthy inflammation is the type of reaction that occurs when you, say,
sprain your ankle.
The area becomes inflamed, which basically means youre probably
experiencing heat, pain, redness and swelling in the area. If you could
take a microscope and see beneath your skin, youd also notice your
immune system being called into action.
During the normal process of acute inflammation, blood vessels become
dilated and permeability increases to improve blood flow to the injured
area.
Immune cells, including neutrophils, are called to the area as well, to
engulf or kill invading organisms. They also release cytokines that help
trigger a systemic inflammatory response (if necessary) such as fever or
an increase in white blood cells.
In some cases, however, this call for immune action doesnt get turned off
as it should after the illness or injury goes away. Instead, your body
remains in a state of chronic inflammation in which your immune cells
continue to release pro-inflammatory chemicals and free radicals.

You may not know that your body is silently simmering but eventually
inflammatory diseases or other inflammation-related damage can result.
As explained by the Linus Pauling Institute:
If the stimulus persists, inflammation can last days, months, and even
years. Chronic inflammation is primarily mediated by monocytes and
long-lived macrophages Macrophages and other leukocytes [immune
system cells] release ROS [reactive oxygen species] and proteases that
destroy the source of inflammation; however, damage to the bodys own
tissues often results.
In fact, tissue damage is a hallmark of chronic inflammation. Another
characteristic of chronic inflammation is repair of the damaged tissue by
replacement with cells of the same type or with fibrous connective tissue.
An important part of the inflammatory process involves local
angiogenesisthe development of new blood vessels. In some instances,
the body is unable to repair tissue damage, and the inflammatory cascade
continues. Chronic inflammation is abnormal and does not benefit the
body; in fact, chronic inflammation is involved in a number of disease
states.
Many factors can trigger chronic inflammation. Obesity, for instance,
makes you prone to chronic inflammation, as does suffering from frequent
infections. If you smoke, are extremely stressed or eat a primarily
processed food diet, chronic inflammation is likely, too.
Exposure to environmental pollution is another common chronic
inflammation trigger even lack of sleep can trigger inflammatory
processes. Once chronic inflammation begins, it can persist for weeks,
months or years, leading to the following health issues.
Watch this Video HERE Forget Cholesterol, Chronic Inflammation Is
The Real Enemy!
11 Ways Chronic Inflammation Harms You
11. Digestive Issues
The definition of inflammatory bowel disease is a chronic inflammation of
your digestive tract. This can manifest as ulcerative colitis, Crohns
disease and more, with symptoms such as diarrhea, abdominal pain and
cramping, and blood in your stool.
Gastritis, which can lead to upper abdominal pain, nausea and vomiting
(or no symptoms at all), is caused by an inflammation of the lining of
your stomach.

10. Joint Pain

Joint pain is a common result of inflammation in your joints. In the case
of rheumatoid arthritis, it is an autoimmune disease that causes
inflammation in your joints.
With anklylosing spondylitis, another rheumatic disease, inflammation
occurs at the site where certain ligaments or tendons attach to bone
(enthesis). Some erosion of bone at the site of the attachment
(enthesopathy) follows this.
As the inflammation subsides, a healing process takes place and new
bone develops. Movement becomes restricted where bone replaces the
elastic tissue of ligaments or tendons. Repetition of this inflammatory
process leads to further bone formation causing backbones and vertebrae
to fuse together.
Even in the case of osteoarthritis, which is characterized by degeneration
of the joints and has long been described as non-inflammatory arthritis,
inflammation is now thought to play a strong role.
9. Heart Disease
Elevated levels of C-reactive protein (CRP), a marker of inflammation in
your body, are associated with an increased risk of heart disease. One
study found that, out of 12 heart-disease risk markers measured, high
CRP was the strongest predictor of the risk of cardiovascular events. Even
among women with low LDL (bad) cholesterol levels, elevated CRP was
still a significant predictor of heart risks.
8. Depression
Cytokines are chemical messengers that signal cells of your immune
system, helping your body to heal from injury. However, cytokines can be
either anti-inflammatory or pro-inflammatory, and when your body is in
an inflammatory state, production of pro-inflammatory cytokines is
increased.
High levels of cytokines, in turn, may contribute to depression. One study
found, for instance, that people with depression had significantly higher
levels of the pro-inflammatory cytokine TNF-alpha, and lower levels of
anti-inflammatory cytokines, than people without depression.
As reported in the journal Neuroscience, inflammatory cytokines play an
important role in brain function, but when exposure becomes chronic it
can negatively influence your mental health:

Mounting evidence indicates that inflammatory cytokines contribute to

the development of depression in both medically ill and medically healthy
individuals. Cytokines are important for development and normal brain
function, and have the ability to influence neurocircuitry and
neurotransmitter systems to produce behavioral alterations.
Acutely, inflammatory cytokine administration or activation of the innate
immune system produces adaptive behavioral responses that promote
conservation of energy to combat infection or recovery from injury.
However, chronic exposure to elevated inflammatory cytokines and
persistent alterations in neurotransmitter systems can lead to
neuropsychiatric disorders and depression.
Its thought that cytokines may activate inflammatory signaling pathways
in your brain and decrease growth factors, such as brain-derived
neurotrophic factor (BDNF), which may play a role in helping damaged
nerve cells regenerate.
7. Oral Health
Inflammation of your gums is known as periodontitis, or gum disease. If
not treated, it can damage the soft tissue and bone that supports your
teeth, and this inflammatory infection is linked to damage elsewhere in
your body as well, including heart disease and dementia. According to
research in Dentistry iQ:
It is increasingly evident that chronic inflammatory conditions in one
organ or tissue of the body may produce systemic effects with deleterious
consequences. For example, an increased level of C-reactive protein is a
risk factor for atherosclerosis, and is correlated with levels of periodontal
inflammation. Some evidence now points to a contributory or causative
role for periodontitis in the pathogenesis of atherosclerosis.
6. Bone Loss and Damage
Chronic inflammation interferes with bone growth and often leads to bone
loss when it occurs in areas close to bone (such as in rheumatoid arthritis
and periodontitis). According to a study in the journal Immunological
Investigations:
This [bone loss due to chronic inflammation] is mainly due to local
formation of bone resorbing osteoclasts which degrade bone without any
subsequent coupling to new bone formation.
5. Chronic Obstructive Pulmonary Disease (COPD)

If you or someone you love has COPD, you should know that
inflammation plays a primary role (hence the common use of antiinflammatory medications). As reported in the Journal of Allergy and
Clinical Immunology:
Chronic obstructive pulmonary disease (COPD) is a progressive
syndrome of expiratory airflow limitation caused by chronic
inflammation of the airways and lung parenchyma.
The airway inflammatory response in COPD is initiated by smoking
in the overwhelming majority of cases, and chronic exposure to
cigarette smoke initiates a series of events that causes damage to central
airways, peripheral airways, and terminal airspaces, leading to physiologic
and clinical abnormalities.
4. Cancer
Many different types of cancer, including breast, lung, esophagus, cervix
and digestive tract, have been linked to inflammation. Research
presented at a meeting of the American Association for Cancer Research
found that teens with high levels of inflammation had a 63 percent
increased risk of developing colorectal cancer, compared with those with
low levels of inflammation. Mansour Mohamadzadeh, PhD, director of the
Center for Inflammation and Mucosal Immunology at the University of
Florida told Health:
When immune cells begin to produce inflammation, immune regulation
becomes deteriorated and it creates an optimal environment for cancer
cells to grow.
3. Dementia
Dementia including Alzheimers disease is also thought to be worsened or
triggered by chronic inflammation, which is known to increase the
generation of amyloid-beta protein. Clumps of beta-amyloid protein are
thought to damage and destroy brain cells.
2. Accelerated Aging
Chronic inflammation is known to trigger the release of powerful free
radicals that accelerate the aging process. In one study, researchers were
able induce premature aging by triggering low-grade chronic
inflammation.
1. Pain

Chronic inflammation is at the root of many painful conditions, and it also

can trigger pain directly. As explained by Medical News Today:
Inflammation primarily causes pain because the swelling pushes
against the sensitive nerve endings, which send pain signals to
the brain.
Nerve endings send pain signals to the brain all day long; however, it
learns to ignore most of them, unless pressure against the nerve endings
increases. Other biochemical processes also occur during inflammation,
which affect how nerves behave, and cause pain.
Because of the inflammation component, non-steroidal anti-inflammatory
drugs (NSAIDs) are often given as a first-line treatment for pain.
However, there are natural techniques to lessen inflammation in your
body.
Try limiting refined foods and sugar, which are pro-inflammatory, and
focus instead on eating an anti-inflammatory diet. You should also
embrace relaxation strategies, as stress can cause and exacerbate
inflammation.
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