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Sarcoidosis (from sarc meaning flesh, -oid, like, and -osis, process), also
called sarcoid,Besnier-Boeck disease or Besnier-Boeck-Schaumann disease, is a disease
in which abnormal collections of chronic inflammatory cells (granulomas) form as nodules in
multiple organs. The cause of sarcoidosis is unknown. Granulomas most often appear in
the lungs or the lymph nodes, but virtually any organ can be affected. Normally the onset is
gradual. Sarcoidosis may be asymptomatic or chronic. It commonly improves or clears up
spontaneously. More than 2/3 of people with lung sarcoidosis have no symptoms after 9 years.
About 50% have relapses. About 10% develop serious disability. Lung scarring or infection may
lead to respiratory failure and death.
Classification of sarcoidosis
Sarcoidosis may be divided into the following types:
Annular sarcoidosis
Erythrodermic sarcoidosis
Ichthyosiform sarcoidosis
Hypopigmented sarcoidosis
Lfgren syndrome
Lupus pernio
Morpheaform sarcoidosis
Mucosal sarcoidosis
Neurosarcoidosis
Papular sarcoid
Scar sarcoid
Subcutaneous sarcoidosis
Systemic sarcoidosis
Ulcerative sarcoidosis
The sign and symptom which related to endocrine is Granulomas in the pituitary gland,
which produces numerous hormones, is rare but leads to any of the symptoms
of hypopituitarism:amenorrhoea (cessation of the menstrual cycle), diabetes
insipidus (dehydration due to inability to concentrate the urine), hypothyroidism(decreased
activity of the thyroid) or hypocortisolism (deficiency of cortisol).