/

AIM OF GSF analYsis:

rr\BOAATOAy ANALvsrs
OT CNS DTSOADEAS

. to assist / help for diagnosis establlshment

'

. to suPPort dlagnosis
. to develop comparative diagnosls
. to asses patient historical disease
. to asses sicknesssevereness
. to conclude Prognosis

vfl

Diana Aulia

Faculty ot Medicine

Hematology Laboratory
DePartmeni of clinical Pathology'
Mansunkusumo I'lospital

u"'i*'Y"illi"lilffi
October

291h,

result: Precise

'f;cipto

acGurate

fast

2012

reliable

Gerebrospinal fluid (GSF) analysis

PRA

INSTRUMENTATION

a
- Laboratory test to examine

d6i;ii,;6 fl,riiluirounding

INSTRUMENTATION

patient
preparation
. collection
. placement
. storage

'quality
assessment

. reporting
. evaluation

'calibration

' quality control

'reagent

thebrain & spinal

iord, cushioning & lubricating the braln ano

sPinal column))

protects CNS from

iniurv & cuahions-it from surrounding oone
li'ruiture, ana lubricate the GNS
x GSF: supply nutrients to the nervous tissue
d CSF: remove metabolic wastes
*t Contains variety of substances (glucose, protein'

u- C'Sf : clear, watery liquid

wBc)

delivery

Bathesthe bnin and

ls Drcduced Primarily
70'%) bY selective
secretion. not as an
ultEfiltate throuEh
choroid Plexuses

GerebrosPinal

spinalcord

Na, Cl,

sample of CSF

Eied:fi

ila$'iso|Fiinqa ld!l sh!s)

Anatomy & Physiology

(t
ou?d

ddl(

Mg > Plasma

ce&K

<

Plasma

lolmed bY the
eendvmal linlng cells ol
llie riticl4 and the
cerdtal/subarachnold

30%

15

3pa@

The bnin and spinal cord

are sunounded bY 3

membEnes ) lermedmeninoes: duEmaler ls

next to bonel;
aachnoidea and Pia
maler

'

csFflows in the space

between the anchnoidea

materand Pia mater

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