Drug Name Dosage & Route Action Indication Adverse Effects Contraindication Nursing Responsibility

FOLIC ACID Therapeutic Vitamin B complex Folate deficiency, Reportedly nontoxic. Folic acidalone for Assessment & Drug Effects
(VITAMIN B9, Adult: essential for macrocytic anemia, and Slight flushing and pernicious anemia or
PTEROYLGLUTAMI PO/IM/SC/IV 1 nucleoprotein synthesis megaloblastic anemias feeling of warmth other vitamin B12
and maintenance of associated with following IV • Obtain a careful
C ACID) mg/d deficiency states;
normal erythropoiesis. malabsorption administration. history of dietary
(fol'ic) Child: normocytic, refractory,
Acts against folic acid syndromes, alcoholism, intake and drug and
PO/IM/SC/IV 1 aplastic, or undiagnosed
deficiency that impairs primary liver disease, alcohol usage prior to
Classifications mg/d anemia.
thymidylate synthesis inadequate dietary start of therapy. Drugs
Vitamin B9 reported to cause
Maintenance and results in intake, pregnancy,
production of defective infancy, and childhood. folate deficiency
Adult:
DNA that leads to include oral
PO/IM/SC/IV
megaloblast formation contraceptives,
0.4 mg/d
and arrest of bone alcohol, barbiturates,
Child:
marrow maturation. methotrexate,
PO/IM/SC/IV <4
phenytoin, primidone,
y, 0.3 mg/d; >4
and trimethoprim.
y, 0.4 mg/d
Folate deficiency may
Infant:
also result from renal
PO/IM/SC/IV
dialysis.
0.1 mg/d
• Keep physician
informed of patient's
response to therapy.
• Monitor patients on
phenytoin for
subtherapeutic plasma
levels.