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Introduction
Breast cancer is
one of the most
dangerous issues
in womens
health currently.
Introduction
The Mediterranean dietary pattern is
studied for its association with many
health conditions
One parameter which defines the
Mediterranean diet is an increased
consumption of olive oil.
Introduction
Polyphenols are known to inhibit the
growth of cancerous cells
Still unknown how consumption of
polyphenols helps
Olive oil is high in polyphenols
Highly phenolic foods defined as
having over 200 mg/kg
Introduction
DOES AN INCREASED
CONSUMPTION OF OLIVE OIL
HAVE A PROTECTIVE EFFECT
AGAINST BREAST CANCER RISK
IN MEDITERRANEAN WOMEN?
Summary
The literature discussed in this paper
largely gives consistent support to
the theory that olive oil consumption
is inversely related to breast cancer
risk in populations of Mediterranean
women.
The consistently significant findings
of many of these studies lose some
of their impact because their study
designs are so similar.
Future Research
Varied study designs
Mechanism of absorption of
polyphenols
Other populations
Conclusions
The hypothesis that olive oil has a protective effect
against breast cancer in Mediterranean women is
supported by the evidence in this paper, however,
there is not enough data to conclude that this
association is universally applicable
The one conclusion that every one of these studies
supports completely is that increasing the proportion
of dietary fat consumed as olive oil has no negative
effects.
Breast cancer is such a pressing concern in womens
health that encouraging this change now will be more
helpful than waiting for an irrefutable conclusion.
References
1. La Vecchia C, Negri E, Franceschi S, Decarli A, Giacosa A, Lipworth L. Olive oil, other dietary fats, and the risk of breast cancer
(Italy). Cancer Causes & Control 1995; 6(6), 545-550.
2. Sieri S, Krogh V, Pala V, Muti P, Micheli A, Evangelista A, Berrino F. Dietary patterns and risk of breast cancer in the ORDET cohort.
Cancer Epidemiology Biomarkers & Prevention 2004; 13(4), 567-572.
3. Masala G, Ambrogetti D, Assedi M, Giorgi D, Del Turco MR, Palli D. Dietary and lifestyle determinants of mammographic breast
density. A longitudinal study in a Mediterranean population. International journal of cancer 2006; 118(7), 1782-1789.
4. Landa MC, Frago N, Tres A. Diet and the risk of breast cancer in Spain. European journal of cancer prevention 1994; 3(4), 313-320.
5. MartinMoreno JM, Willett WC, Gorgojo L, Banegas JR, RodriguezArtalejo F, FernandezRodriguez JC, Boyle P. Dietary fat, olive oil
intake and breast cancer risk. International Journal of Cancer 1994 ; 58(6), 774-780.
6. Garca-Segovia P, Snchez-Villegas A, Doreste J, Santana F, Serra-Majem L. Olive oil consumption and risk of breast cancer in the
Canary Islands: a population-based casecontrol study. Public health nutrition 2006; 9(1a), 163-167.
7. Cottet V, Touvier M, Fournier A, Touillaud MS, Lafay L, Clavel-Chapelon F, Boutron-Ruault MC. Postmenopausal breast cancer risk
and dietary patterns in the E3N-EPIC prospective cohort study. American journal of epidemiology 2009; 170(10), 1257-1267.
8. Salvini S, Sera F, Caruso D, Giovannelli L, Visioli F, Saieva C, Palli D. Daily consumption of a high-phenol extra-virgin olive oil
reduces oxidative DNA damage in postmenopausal women. British journal of nutrition 2006; 95(04), 742-751.
9. Trichopoulou A, Bamia C, Lagiou P, Trichopoulos D. Conformity to traditional Mediterranean diet and breast cancer risk in the Greek
EPIC (European Prospective Investigation into Cancer and Nutrition) cohort. The American journal of clinical nutrition 2010; 92(3),
620-625.
Image Credits
http://www.saintfrancis.com/breastServices/
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Martin-Moreno et al. (5)
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