B2 6.

5
Homework sheet
Name:

Class:

Sickle cell anaemia SUMMARY SHEET

Aim
To use your knowledge, textbooks and/or the Internet to research sickle cell anaemia an
inherited condition of the blood.

Questions
Sickle cell anaemia is an inherited condition of the blood.
1

In the spaces provided, draw the appearance of normal red blood cells and cells affected by this
disease.

Normal red blood

Sickle red blood

cells

cells

What problems result from having sickle red blood cells?

............................................................................................................................................................

Is sickle cell anaemia caused by a dominant or a recessive allele?

............................................................................................................................................................

Use this diagram to describe the cause of sickle cell anaemia.

AQA Science Nelson Thornes Ltd 2006

B2 6.5

B2 1.1
Homework sheet
Continued

Use a genetic diagram (Punnett square) to show how a child could inherit the disease. [Higher]

Where in the world is this disease especially common?

............................................................................................................................................................

Explain the connection between sickle cell anaemia and malaria.

............................................................................................................................................................

8. Look at the punnet square below.

Figure 1
1

(Grand parents)

Key
3

unaffected male

unaffected female

(Parents)
affected male
5

10

11

(Children)

affected female

male carrier
12

13

14
female carrier

Why must parents 6 and 7 be carriers of sickle cell.

Calculate the percentage chance of child 14 also being a carrier.

AQA Science Nelson Thornes Ltd 2006

B2 1.1