CSE235 Introduction to Bioinformatics

SPRING-2016
Final Exam Syllabus with short guideline:
1. Bioinformatics-Lecture06 and 07:
What is Sequence Alignment? why?
Global VS Local Alignment
Sequence Scoring***
Common Mutations**
Terminology (Homolog, Ortholog, Paralog)
Similarity VS Homology.
2. Multiple Sequence Alignment:
Multiple Alignment: Dynamic Programming***
Global msa: Challenges *
3. Bioinformatics-Database Search (Fasta):
Sensitivity and Selectivity
BLAST VS FASTA
Searching for local similar regions using FASTA (Hashing Example).***
Basic Databases Names and its inventor
4. Bioinformatics-HMM:
Markov Chain Model Definition, Property ***
CpG Islands ***
Drawing a Markov Model ( Forward and Viterbi Algorithm) [10 Marks] ***

[MD. Saidur Rahman Kohinoor] | [Thursday, April 21, 2016]