Professional Documents
Culture Documents
, Mekni,
A., Nidhameddine, K., Haouet, S., et
al. (2007). Primary Cutaneous
Leiomyosarcoma: A histological and
immunohistochemical study of 4
cases. Egyptian Dermatology Online
Journal , 3 (1).
3Bio2
Abstract
Methodology
Surgical
excision
Hematoxy
lin &
Eosin
staining
Note: Only the following information regarding the methodology is available due to the
article being a case report
Results
CASE 1
CASE 2
CASE 3
CASE 4
Location
Chin
Scrotum
Lower lip
Shoulder
Growth
pattern
Nodular
Nodular
Nodular
Nodular
Atypia
Moderate
Marked
Mild
Moderate
Giant
multinucleat
e cells
Necrosis
+ (<50%)
+ (<50%)
Ulceration
Extension to
subcutaneo
us fat
Histological
Grade
Grade 2
Grade 2
Grade 2
Grade 2
Results
Conclusion
In the presence of a small biopsy,
PCL may be misinterpreted as benign
smooth muscle proliferation such as
leiomyoma. Therefore, careful scrutiny
of cytological details in multiple
sections, clinicopathological correlation
and
immunohistochemistry
are
mandatory for definitive diagnosis.
Local
recurrence
and
distant
metastasis can occur years after the