treated in the community For patients treated in the community, amoxicillin remains the preferred agent at a dose of 500 mg three times daily. [A+] Either doxycycline [D] or clarithromycin [A] are appropriate as an alternative choice, and for those patients who are hypersensitive to penicillins. Those with features of moderate or high severity infection should be admitted urgently to hospital. [C]
Gua IDSA Outpatient
treatment 15. Previously healthy and
no risk factors for drug-resistant S. pneumoniae (DRSP) infection: A. A macrolide (azithromycin, clarithromycin, or erythromycin) (strong recommendation; level I evidence) B. Doxycycline (weak recommendation; level III evidence)