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TUBERCULOSIS

Mycobacterium Tubercle Bacilli


Transmitted thru Airway

LYMP SYSTEM ALVEOLI KIDNEY,BONES,CEREBRAL CORTEX, LYMP SYSTEM

INFLAMMATORY REACTION

Phagocytesneutrophils,macrophages,TB
specific lymphocytes(lyse the bacilli &
normal cell)

Accumulation of exudates in alveoli Granulomas (fibrous tissue mass)

Bronchopneumonia

Necrosis
(CHESSY MASS)

GHON TUBERCLE ULCERATE Scar


Bacteria is dormant

RELEASE CHESSY MATERIAL IN


LUNG BECOMES
BRONCHI
MORE INFLAMED Possible activation
S/S: Reason: Compromise person
 LOW GRADE FEVER
 COUGH (NON PRODUCTIVE MUCOPURULENT)
 NIGHT SWEAT
 FATIGUE
 WEIGHT LOSS
 HEMOPTYSIS
DIAGNOSTIC TEST
 X-RAY  PRESENCE AND EXTENT OF THE DISEASE
 ACID FAST BACILLI
 SPUTUM CULTURE
 TUBERCULIN SKIN TEST- (MANTOUX TEST)-to determine whether the pt. has been infected with
the TB bacillus.
PPD-purified protein derivative
-intradermal (4 inches below the elbow), 26-27 G needle, intermediate strength PPD
-result read within 48-72hours
-induration o-4 mm not significant
5 and above significant in person who considered to be at risk

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