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Generic name: For Hypokalemia and Acute renal insufficiency and Gynecomastia; GI When prolong may
Spironolactone Spironolactone is Hypertension. Hyperkalemia. lead to renal
symptoms; drowsiness,
impairement.
a specific lethargy; headache,
Brand name: Concomitant use
pharmacologic mental confusion, ataxia;
Aldactone w/ other K-
antagonist of impotence; menstrual
aldosterone, irregularities, post- retaining drugs or
Classification:
Diuretics acting primarily menopausal bleeding. K supplements
through
Dosage: competitive
50 mg ½ tab binding of
receptors at the
Route:
Oral aldosterone-
dependent
Frequency: sodium-potassium
BID exchange site in
the distal
convoluted renal
tubule. It causes
increased
amounts of
sodium and water
to be excreted,
while potassium is
retained.