THE BRITISH INTERNATIONAL SCHOOL

UNIT 4 –A LEVEL BIOLOGY CLASS TEST

Name: Date :

Total marks : 30
1. The flow diagram below is the first stage of humoral response in a specific
response to a bacterial infection.
( 6 marks )

Bacterium with A on
surface

Bacterium engulfed
by B

B presents the A from the

bacterium on Major
histocompatibility complexes
(MHCs). It becomes C

A CD4 macrophage APC binds to a

D with complementary CD4
receptors. Once the D is
activated, it divides to form E and
(i) Identify A, B, C, D, E and F by writing appropriate terms in the spaces
below.
A _______________________ B_______________________

C_______________________ D_______________________

E_______________________ F_______________________
1. Explain in detail Cell – mediated response with an illustration. ( 10 marks )
2. Choose the one best answer ( 5 marks )

1. Any foreign material that can get inside your body and make you sick is
called ____________________
a. T cell
b. pathogen
c. phagocyte
d. non-specific response

2. T cells are _______________________________________________

a. made in bone marrow but mature in the thymus
b. made in the thymus but mature in bone marrow
c. made and mature in bone marrow
d. made and mature in the thymus

3 An antigen is ___________________.
a. any molecule that the body recognizes as foreign
b. the DNA or RNA of an intective pathogen
c. an alternate term for an MHC complex
d. the collection of circulating proteins which kill or tag microbes

4.. Memory cells play a vital immune role __________________________

a. when you are first exposed to a pathogen
b. when you are exposed to a disease for the second time
c. in non-specific immunity
d. in the primary immune response

5. All antibodies are known as

a. Immunoglobulins.
b. MHC
c. Lymphocytes.
d. Interferons.
4. What are the four key characteristics of the immune system? ( 4 marks )
5. How does the antibodies contribute to the defence of the body against the
invasion of foreign material? ( 5 marks )