DRUG STUDY

Generic & Brand Name, Classificat ion

Generic: Amlodipine

Dose, Strength & Formulati on

Ordered: Give 10 mg 1tab, OD

Indication/Mechani sms of Drug Action

Adverse/Side Effects Drug Interaction

Nursing Responsibilit ies

Assessment:

Rationale

Client Teaching

Indications: Angina pectoris due to coronary artery Spasm, Chronic stable angina, alone or in combination with other agents, Essential hypertension, alone or in combination with other antihypertensive, Mechanism of Action: Inhibits the movement of calcium ions across the membranes of cardiac and arterial muscle cells; inhibits transmembrane calcium flow, which results in the depression of impulse formation in specialized cardiac pacemaker cells, slowing of the velocity of conduction of the cardiac impulse, depression of myocardial contractility, Adverse Effect: CNS: Dizziness, lightheadedness, headache, asthenia, fatigue, lethargy CV: Peripheral edema, arrhythmias Dermatologic: Flushing, rash GI: Nausea, abdominal Discomfort

BEFORE:

Brand: Norvasc

Timing: 8 am Duration:

Classificati on: Calcium channelblocker Antianginal Drug Antihyperten sive

24 hrs. Other forms: Tablets: 2.5 mg, 5 mg, 10 mg

Obtain patients history to allergy of amlodipine . Assess vital signs before therapy. DURING: Monitor patients BP, cardiac rhythm Interactions: Monitor Drug-drug intake and Possible output. increased serum AFTER: levels and toxicity Monitor of cyclosporine if vital signs. Taken Be alert for concurrently.

*To indicate if the patient can have this medication. *To obtain baseline data. *Drug can cause hypotension, careful monitoring needed. *To assess hepatic impairment. * To stop medication if BP is < 90 mmHg or heart rate <

>Advice patient to take medication as directed, even if feeling well. >Take missed doses as soon as possible unless Almost time for next dose; do not double doses. > Caution patient to change positions slowly to minimize orthostatic Hypotension. > Advise

and dilation of coronary arteries and arterioles and peripheral arterioles; these effects lead to decreased cardiac work, decreased cardiac oxygen consumption, and in patients with vasospastic angina, increased delivery of oxygen to cardiac cells.

adverse effect.

50 bpm. *to establish proper precautionary measures.

patient to notify health care professional if irregular heartbeats, dyspnea, swelling of hands and feet, pronounced dizziness, nausea, constipation, or hypotension