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HLDA9
Markers Expressed By Most Leukocytes CFU-GEMM Myeloid Stem Cell
CD33 CD34 CD110* CD111* CD112* CD117 CD123 CD131 CD133* CD173* CD174* CD176 CD227* CD228 CD280
MYELOID MYE L OI D
LYMPHOID
Lymphoid Stem Cell
CD10 CD34 CD38 CD90* CD117 CD124 CD127 CD228
BONE MARROW
Subcortical Thymocyte
CD2 CD4 CD5 CD7 CD8 CD38 CD200
Cortical Thymocyte
CD1a CD1b CD1c CD2 CD3 CD4 CD5 CD7 CD8 CD38 CD52 CD165 CD200
CFU-Meg
CD34 CD110 CD123
CFU-M
CD13 CD15 CD33 CD111 CD112 CD115 CD116 CD123 CD131
CFU-G
CD13 CD15 CD33 CD111 CD112 CD116 CD123 CD131
CFU-Eo
CD13 CD33 CD34 CD116 CD123 CD131
CFU-Bas
CD34 CD123
Medullary Thymocyte
CD4*
Medullary Thymocyte
CD8*
Reticulocyte
Megakaryocyte
CD41 CD42a CD42b CD42c CD42d CD49f (CD51) CD61 CD110 CD123 CD131 CD203c
Promonocyte
CD13 CD14 (CD15*) CD33 CD111 CD112 CD115 CD116 CD123 CD131
Myelocyte
CD13 (CD15*) (CD33) CD111 CD112 CD114 CD116 CD123 CD131
Myelocyte
CD11b CD13 (CD15*) CD32 CD33 CD35 CD114 CD116 CD131
Myelocyte
(CD15*) CD33 CD114 CD123
Immature B Cell
CD19 CD20 CD21 CD22 CD24 CD32 CD35 CD37 CD40 CD48 CD52 CD72 CD74 CD75 CD75s CD79a CD79d CD80* (CD85) CD99 CD124 CD210 (CD267) CD268 CD269 CD275 CD316 CD317
Erythrocyte
Platelets
Monocyte
Neutrophil
Eosinophil
Basophil
Cytotoxic/Suppressor T Lymphocyte
CD8*
BLOOD
CD35 CD44 CD55 CD59 CD147 CD173 CD233 CD234 CD235a CD235b CD236
CD9 CD17 CD23 CD31 CD36 CD41 CD42a CD42b CD42c CD42d CD49b CD49f
(CD51) CD60a CD61 CD84 CD92 CD109 (CD110) CD147 CD151 CD173 CD226
+ Activated Platelets
CD62P CD63 CD107a CD107b
(CD4) CD9 CD11b CD11c CDw12 CD13 CD14 CD15 CD17 (CD31) CD32 CD33 CD35 CD36 CD38 (CD40) CD43 (CD45RO) (CD45RA) (CD45RB) CD49b CD49e CD49f
CD63 CD64 CD65s CD68 (CD74) CD84 CD85 CD86 CD87 CD89 CD91 CD92 CD93 CD98 CD101 CD102 CD111 CD112 CD115 CD116 CD119 CD121b CD123
CD127 CD128b CD131 CD142* CD147 CD155 CD156a CD157 CD162 CD163 CD164 CD168 (CD170) CD171 CD172a CD172b CD180 CD184 CD191 CD192 CD195 CDw198 CD206
CD210 CD213a1 CD213a2 CD226 CD277 CD281 CD282 CD284* (CD295) CD300a CD300c CD300e CD302 CD305 CD312 CD317 CD322 CD328 CD329 CD351 (CD 352) CD353 CD362
CD10 CD15s CD16d CD17 CD24 CD32 CD35 CD43 CD65 CD65s
CD66a CD66d CD89 CD92 CD93 CD111 CD112 CD114 CD116 CD123
+ Activated Neutrophil
CD64 CD66
+ Activated Eosinophil
CD23 CD64 CD66
+ Activated Basophil
CD64 CD66
CD5* CD19 CD20 CD21 CD22 CD24 CD32 CD35 CD37 (CD39) CD40 CD48 CD49b CD49c CD49d CD52 CD72
CD74 CD75* CD75s* CD78 CD79a CD79b CD80* CD84 (CD85) (CD98) CD99 CD102 CD119 CD121b CD124 CD171* CD180*
CD185 CD192 CD196 CD210 CD213a1 CD213a2 (CD229) CD218a CD218b (CD2267) CD268 (CD269) (CD275) CD277 CD305 CD316 CD317
CD319* CD322 CD327 (CD351) CD352 (CD353) (CD354) CD355 (CD357) CD358 CD360 CD362 CD363
CD2 CD3 CD5 CD6* CD7 CD11c* (CD27*) CD28* CD31 CD35 (CD37)
CD43 CD45RB* CD45RC* CD48 CD49d (CD49f) CD57* CD60a* CD60b CD60c (CD70)
CD75s* CD73* (CD75*) CD94* CD98 CD99 CD101* CD102 CD103* CD121a CD122*
CD124 CD137* CD147* CD150 CD158a* CD158b* CD160* CD161 CD162 CD164 CD171*
CD172a* CD172g CD181* CD182* CD184* CD185* CD186* CD191 CD192* CD193* CD195*
CD196* CDw198* CDw199* CD210 CD215 CD218a CD218b CD226 (CD229) CD244* CD245*
CD247 CD277 CD296 CD305 CD316 CD317 CD319* CD322* CD328 CD351 CD352
Helper/Inducer T Lymphocyte
CD4* CD272* CD45RO* CD294* CD197
Activated T Cell
CD2R CD25 CD26 CD30 CD38 CD49b CD49e CD49f CD69 CD70 CD71 (CD83) CD87 CD96 CD108 CD109 CD134* CD146 CD152 CD153 CD154 CD166 CD178 CD183 CD212 CD223 CD253 CD254 CD258 CD267 CD273 CD274 CD278 CD279
Macrophage
LYMPH NODE
(These cells move between the bone marrow, blood, and tissue.)
TISSUE
Endothelial Cells
CD54 CD62E CD92 CD93 CD102 CD105 CD106 CD109 CD116 CD121a CD124 CD140b CD141 CD142* CD143* CD144 CDw145 CD146 CD141 CD142* CD143* CD144 CDw145 CD146 CD202b CD213a1 CD213a2 CD249 CD252 CD266* CD280* CD299* CD309 CD322 CD325
CD11c CD14 CD16 CD26 CD31 CD32 CD36 CD45RO CD45RB CD63 CD68
CD71 CD74 CD87 CD88 CD101 CD119 CD121b CD155 CD156a CD169* CD170*
CD204 CD206 CD210 CD280* CD312 CD351 CD353 CD354 CD357 CD358 CD360
Activated B Cell
CD5* CD10 CD19 CD20 CD21 CD22 CD24 CD32 CD35 CD37 CD38 (CD39) CD40 CD48 CD49b CD49c CD49d CD52 CD72 CD74 CD75* CD75s* CD77 CD78 CD79a CD79b CD80* CD84 (CD85) (CD98) CD99 CD102 CD119 CD121b CD124 CD171* CD180* CD185 CD192 CD196 CD210 CD213a1 CD213a2 (CD229) CD218a CD218b (CD2267) CD268 (CD269) (CD275) CD277 CD305 CD316 CD317 CD319* CD322 CD327
Dendritic Cells
CD85 CD172b CD180 CD187 CD193 CD196 CD205 CD206* CD207* CD208* CD209* CD218a* CD218b* CD252 CD258* CD265 CD271* CD273 CD274 CD275 CD276a* CD277 CD283 CD289* CD300a CD300b CD301* CD302 CD303* CD304* CD312* CD317 CD319* CD320* CD352 CD354 CD357
Stromal Cells
CD90 CD121a CD140b CD166 CD248 CD254 CD271 CD280 CD283 CD331 CD332 CD333 CD334 CD339
+ Activated Macrophage
CD23 CD25 CD69 CD105
Memory B Cell
CD5* CD19 CD20 CD21 CD22 CD24 CD27 CD32 CD35 CD37 (CD39) CD40 CD48 CD49b CD49c CD49d CD52 CD72 CD74 CD75* CD75s* CD78 CD79a CD79b CD80* CD84 (CD85) (CD98) CD99 CD102 CD119 CD121b CD124 CD171* CD180* CD185 CD192 CD196 CD210 CD213a1 CD213a2 (CD229) CD218a CD218b (CD2267) CD268 (CD269) (CD275) CD277 CD305 CD307a CD316 CD317 CD319* CD322 CD327
Immunoblast
CD10 CD19 CD20 CD22 CD24 CD27 CD37 CD38 (CD39) CD40 CD72 CD74 CD79a CD79b CD139 CD275 CD316 CD317
Plasma Cell
CD38 CD79a CD126 CD138 CD269 CD275 CD307a CD316 CD317
CD
CD1a CD1b CD1c CD2 CD2R CD3 CD4 CD5 CD6 CD7 CD8 CD9 CD10 CD11a CD11b CD11c CDw12 CD13 CD14 CD15 CD15s CD15u CD16a CD16b CD17 CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42a CD42b CD42c CD42d CD43 CD44 CD44R CD45 CD45RA CD45RB CD45RC CD45RO CD46 CD47 CD47R CD48 CD49a CD49b CD49c CD49d CD49e CD49f CD50 CD51 CD51/61 CD52 CD53 CD54 CD55 CD56 CD57 CD58 CD59 CD60a CD60b CD60c CD61 CD62E
Other Names
CD
CD62L CD62P CD63 CD64 CD65 CD65s CD66a CD66b CD66c CD66d CD66e CD66f CD67 CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD75 CD75s CD77 CD79a CD79b CD80 CD81 CD82 CD83 CD84 CD85 CD86 CD87 CD88 CD89 CD90 CD91 CD92 CD93 CD94 CD95 CD96 CD97 CD98 CD99 CD99R CD100 CD101 CD102 CD103 CD104 CD105 CD106 CD107a CD107b CD108 CD109 CD110 CD111 CD112 CD113 CD114 CD115 CD116 CD117 CD118 CD119 CD120a CD120b CD121a CD121b CD122 CD123 CD124 CD125 CD126 CD127 CD129 CD130 CD131 CD132 CD133 CD134 CD135 CD136
Other Names
L-Selectin, LECAM-1 P-Selectin, LECAM-3 FcRI
CD
CD137 CD138 CD139 CD140a CD140b CD141 CD142 CD143 CD144 CDw145 CD146 CD147 CD148 CD150 CD151 CD152 CD153 CD154 CD155 CD156a CD156b CD156c CD157 CD158 CD158a CD158b CD159a CD159c CD160 CD161 CD162 CD162R CD163 CD164 CD165 CD166 CD167a CD168 CD169 CD170 CD171 CD172a CD172b CD172g CD173 CD174 CD175 CD175s CD176 CD177 CD178 CD179a CD179b CD180 CD181 CD182 CD183 CD184 CD185 CD186 CD191 CD192 CD193 CD194 CD195 CD196 CD197 CDw198 CDw199 CD200 CD201 CD202b CD203c CD204 CD205 CD206 CD207 CD208 CD209 CDw210 CD212 CD213a1 CD213a2 CD215 CD217 CD218a
Other Names
4-1BB SYNDECAN-1 PDGF Receptor a PDGF Receptor b Thrombomodulin Tissue Factor Angiotensin Converting Enzyme VE-CADHERIN MUC18/S-endo Neurothelin/Basigin HPTP-ETA/DEP-1 SLAM PETA-3 CTLA-4 CD30 Ligand CD40 Ligand Poliovirus Receptor ADAM8 TACE/ADAM17 ADAM-10 BST-1 p58.1 p58.2 NKG2A NKG2C By55 NKR-P1 PSGL-1 PEN5 KiM4 MGC-24 AD2/gp37 ALCAM, CD6 Ligand Discoidin Domain Receptor, DDR1 RHAMM Sialoadhesin Siglec-5 L1 SIRP a SIRP b1 SIRP g, SIRP b2 Blood group H type 2 Lewis Y TN Sialyl-Tn Thomson-Friedrenreich Antigen NB1 Fas Ligand VPREB1 Lambda 5 Rp105/Bgp 95 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6, BONZO CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 OX-2 PROCR, EPCR Tie/Tek NPP3 Macrophage Scavenger Receptor DEC-205 Macrophage Mannose Receptor Langerin DC-LAMP DC-SIGN IL-10R IL-12Rb1 IL-13Ra1 IL-13Ra2 IL-15RA IL-17R IL-18Ra
CD
CD218b CD220 CD221 CD222 CD223 CD224 CD225 CD226 CD227 CD228 CD229 CD230 CD231 CD232 CD233 CD234 CD235a CD235b CD236 CD236R CD238 CD239 CD240CE CD240D CD241 CD242 CD243 CD244 CD245 CD246 CD247 CD248 CD249 CD250 CD251 CD252 CD253 CD254 CD255 CD256 CD257 CD258 CD259 CD260 CD261 CD262 CD263 CD264 CD265 CD266 CD267 CD268 CD269 CD270 CD271 CD272 CD273 CD274 CD275 CD276 CD277 CD278 CD279 CD280 CD281 CD282 CD283 CD284 CD285 CD286 CD287 CD288 CD289 CD290 CD291 CD292 CDw293 CD294 CD295 CD296 CD297 CD298 CD299 CD300a CD300c CD300e CD301 CD302
Other Names
IL-18Rb Insulin Receptor IGF-1 Receptor IGF-2 Receptor, Mannose 6-phosphate Receptor LAG-3 Gamma Glutamyl Transferase (GGT) Leu-13 DNAM-1 MUC-1 Melanotransferrin Ly-9 Prion Protein TALLA-1 VESPR (Plexin C1) Band 3 Duffy Glycophorin A Glycophorin B Glycophorin C/D Clycophorin C Kell B-CAM, Lutheran Rhesus 30 CE Rhesus 30 D Rhesus 50 Glycoprotein ICAM-4 MDR-1 2B4 p220/240 Anaplastic Lymphoma Kinase TCR zeta chain Endosialin Aminopeptidase A
CD
CD303 CD304 CD305 CD306 CD307a CD307b CD307c CD307d CD307e CD308 CD309 CD310 CD311 CD312 CD313 CD314 CD315 CD316 CD317 CD318 CD319 CD320 CD321 CD322 CD323 CD324 CD325 CD326 CD327 CD328 CD329 CD330 CD331 CD332 CD333 CD334 CD335 CD336 CD337 CD338 CD339 CD340 CD344 CD349 CD350 CD351 CD352 CD353 CD354 CD355 CD357 CD358 CD360 CD361 CD362 CD363
Other Names
BDCA2 BDCA4, Neuropilin LAIR-1 LAIR-2 FCRL1 FCRL2 FCRL3 FCRL4 FCRL5 VEGFR2, FLK1, KDR
EMR2
Activation Inducer Molecule Transferrin Receptor ECTO-5 Nucleotidase Invariant Chain Lactosamines a-2, 6-sialylated Lactosamines MB-1 B29 B7-1 TAPA-1 HB15
Aminopeptidase N Lewis X Sialyl Lewis X Sulfated Lewis X FcRIII A FcRIII B Lactosylceramide b2 Integrin
NKG2D CD9P1, SMAP6 EW12, IgSF8 BST2, HM1,24 CDCP1, SIMA135 CRACC, SLAMF7 8D6 JAM-1, F-11R JAM-2, VE-JAM E-Cadherin, Cadherin 1 N-Cadherin, Cadherin 2 Ep-CAM Siglec6, OB-BP1 Siglec7, AIRM1 Siglec9 FGFR1, FLT2 FGFR2, KGFR FGFR3, JTK4 FGFR4, JTK2 NKp46, NCR1, Ly94 NKp44, NCR2, Ly95 NKp30, NCR3, Ly117 ABCG2, BCRP Jagged1, JAG1 HER-2 FZD4 FZD9 FZD10 FCA/MR SLAMF6, NTB-A, KAL.1, Ly108 SLAMF8, BLAME TREM1 CRTAM TNFRSF18, GITR TNFRSF21, DR6 IL-21A EV12B Syndecan-2, SDC2, HFGP1 SIPR1, EDG-1, CHEDG1
B7-2 UPA Receptor C5a Receptor Fca Receptor THY-1 a2 Macroglobulin Receptor
GPIIb/IIIa, aIIb Integrin GPIX GPIB-a GPIB-b GPV Leukosialin H-CAM, Pgp-1 Leukocyte Common Antigen
ICAM-2 HML-1, aE Integrin b4 Integrin Endoglin VCAM-1 LAMP-1 LAMP-2 Platelet Activation Factor Thrombopoietin Receptor, Mpl PRR, Nectin-1 PRR2, Nectin-2 PRR3, Nectin-3 G-CSF Receptor M-CSF Receptor GM-CSF Receptor a Chain SCF-Receptor, c-kit LIF Receptor IFNg Receptor TNF Receptor, Type 1 TNF Receptor, Type 2 IL-1 Receptor, Type 1 IL-1 Receptor, Type 2 IL-2 Receptor b Chain IL-3 Receptor a Chain IL-4/IL-13 Receptor IL-5 Receptor a Chain IL-6 Receptor a Chain IL-7 Receptor a Chain
TRAIL-R1, APO2 TRAIL-R2, DR5 TRAIL-R3, DcR1 TRAIL-R4, DcR2 RANK, TRANCE-R TWEAK-R TACI BAFF-R BCMA TNFRSF14, LIGHTR NGFR BTLA B7-DC, PD-L2 B7-H1, PD-L1 ICOSL B7-H3 (long) BT3.1, BTF5
Activated T cells ICOS, AILIM Activated T cells, Activated B cells PD1 Myeloid progenitors, Fibroblasts, Endothelial cell subset, Endo180, TEM22 Macrophage subset Monocytes, Neutrophils Monocytes, Neutrophils Fibroblasts, Dendritic cells Monocytes (weak) Reserved for TLR5 Monocytes, Dendritic cells, Endothelial cells Reserved for TLR7 Peripheral blood leukocytes, Monocytes, Dendritic cells Dendritic cell subset, Activated B cells B lymphocytes, Dendritic cells Reserved for TLR11 Bone progenitor cells Bone progenitor cells Th2 cells, Eosinophils, Basophils Broad, Monocytes (weak) Epithelial cells, Muscle, T cell subset, Myeloid cell subset Red cells, Erythroblasts, Activated monocytes Broad Endothelial cell subset Dendritic cells, Monocytes, Lymphocyte subsets Dendritic cells, Monocytes, Lymphocyte subsets Monocytes Immature dendritic cells Granulocytes, Monocytes, Dendritic cells TLR1, TIL TLR2, TIL4 TLR3 TLR4 TLR6 TLR8 TLR9 TLR10 BMPR1A BMPR1B CRTH2, GPR44 LEPR, OBR ART1 ART4, Dombrock Blood Group Na, K ATPase b3 Subunit DC-SIGNR, L-SIGN CMRFH CMRF35A CMRF35L1 MGL, CLECSF14 DCL1
VLA-1, a1 Integrin VLA-2, a2 Integrin VLA-3, a3 Integrin VLA-4, a4 Integrin VLA-5, a5 Integrin VLA-6, a6 Integrin ICAM-3 aV Integrin CAMPATH-1 ICAM-1 Decay Accelerating Factor N-CAM HNK-1 LFA-3 Protectin, Homologous Restriction Factor GD3 9-0-sialyl GD3 7-0-sialyl GD3 b3 Integrin, GPIIIa E-Selectin, ELAM-1
Antigen Expression: This table provides brief data regarding the cellular distribution of the various CD markers. In many cases antigens are expressed by small subsets of other leukocytes, or by some other tissues within the body. CD antigen expression in the cells in the top section is shown in three ways: CD000 (CD000) CD000* Strong Expression Weak Expression Subset Expression
gp130 Receptor Subunit for IL-6, IL-11, LIF, OSM LNTF, CT-1 Common b Chain for IL-3, IL-5, GM-CSF Receptor Common g Chain for IL-2, IL-4, IL-7, IL-9, IL-15 Receptors AC-133 OX40 Fit3/Flk2 Macrophage Stimulating Protein Receptor
Further details Indicates that antibodies against this CD marker are available from AbD Serotec. An interactive poster with datasheet links is available on our website. Information related to CD antigens is available online at www.HCDM.org and www.HLDA9.org. ILT and KIR family member information is available online at: http://imgt.cines.fr/textes/IMGTeducation/Tutorials/NKreceptors/_UK/LIR.html. Copyright MorphoSys UK Ltd 2010. All rights reserved. Published by MorphoSys UK Ltd, Endeavour House,Langford Business Park, Langford Lane, Kidlington, Oxford OX5 1GE, UK
LIT.CDPOSTER.CMR.2010.1
www.abdserotec.com
TISSUE
BLOOD
Mature B Cell
(also found in tissues) CD2* CD56 CD160* CD7* CD57 CD161 CD8* CD69 CD162R* CD11b CD94 CD210 CD11c CD122 CD226 CD16 CD158a CD244 CD35* CD158b CD247 CD48 CD159
BONE MARROW
THYMUS