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The two methods for creation of the CAD model of the anatomical axis of femur will be presented in this paper. These methods are: GCM (Gravity Center Method), and CPM (Curve Projection Method). Both methods enable creation of femur anatomical axis geometrical model, which is based on data acquired from the medical imaging devices (CT, MRI, X-Ray). The basic difference between these two methods and the other applied for the geometrical modeling of femur anatomical axis is in the manner of generating the points through which 3D curve passes (or goes near). The technique applied is developed considering the natural shape of the femur bone, and not just by using standard CAD techniques for geometrical modeling which are common in standard engineering. The application of these methods can be extended to other bones in human body as in the fast creating of the model for the use in planning orthopedic operations, the input models for rapid prototyping, designing of implants, etc.

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28. - 30. September 2011, Ni, Serbia University of Ni, Faculty of Mechanical Engineering METHODS FOR CREATING GEOMETRICAL MODEL OF FEMUR ANATOMICAL AXIS

Nikola VITKOVI1, Jelena MILOVANOVI1, Miroslav TRAJANOVI1, Nikola KORUNOVI1, Milo STOJKOVI1 , Miodrag MANI1 1 University of Ni, Faculty of Mechanical Engineering in Ni, A. Medvedeva 14, Ni, Serbia vitko@masfak.ni.ac.rs, jeki@masfak.ni.ac.rs,nikola.korunovic@masfak.ni.ac.rs, traja@masfak.ni.ac.rs, miloss@masfak.ni.ac.rs, mmanic@masfak.ni.ac.rs Abstract: The two methods for creation of the CAD model of the anatomical axis of femur will be presented in this paper. These methods are: GCM (Gravity Center Method), and CPM (Curve Projection Method). Both methods enable creation of femur anatomical axis geometrical model, which is based on data acquired from the medical imaging devices (CT, MRI, X-Ray). The basic difference between these two methods and the other applied for the geometrical modeling of femur anatomical axis is in the manner of generating the points through which 3D curve passes (or goes near). The technique applied is developed considering the natural shape of the femur bone, and not just by using standard CAD techniques for geometrical modeling which are common in standard engineering. The application of these methods can be extended to other bones in human body as in the fast creating of the model for the use in planning orthopedic operations, the input models for rapid prototyping, designing of implants, etc. Key words: Anatomical axis, femur shaft, surface, curve, geometrical model

1. INTRODUCTION

The main goal of this research is to develop CAD modeling method which enables creation of accurate geometrical model of the anatomical axis of femur (3D curve). The other important goal is to cultivate a method which is easy and quick to perform. Previous studies show that it is difficult to achieve these goals simultaneously, as the realization of one may obstruct the realization of the other. This paper presents two different methods which attempt to accomplish the appointed goals to the greatest extent possible. These methods are: GCM (Gravity Center Method) which conforms to the anatomical, morphological and geometrical properties of the femur, CPM (Curve Projection Method) which conforms to the position, topology and geometrical properties of the femur.

To check the integrity of the developed method adequate dimensions were chosen, and the comparison was made with the already established and determined values in anatomy, orthopedic surgery and practice (presented by Cong-Feng Luo in [2]). For this analysis three angles were measured and compared: Anatomical Axis Neck axis (AN), mean value about 126 Distal condylar angle (DC) , mean value about 81 Anatomical axis Mechanical axis (AM), mean value about 6 - 8 Angles were measured in Anterior Posterior plane [1] of the femur bone model. These angles were chosen since they are often used in clinical anatomy and surgery to determine the proper position and orientation of lower limb bones.

1.1.

The geometrical analysis of the femur (shaft) is based on the reverse modeling of the scanned samples by CAD (computer-aided design) software. The reverse modeling begins with importing the coordinates of the points of scanned tissue (from CT) into the appropriate CAD software. The next step is to create a valid polygonal model by using CAD software features and to define referential geometrical entities (detailed explanation of RGE in [1] by Milos et al.). The final step is to apply methods for the creation of valid geometrical model of femur anatomical axis.

The developed methods can have multiple benefits (or uses) in medicine and technology. The geometrical model (3D curve) of the anatomical axis of femur can be used for the creation of the femur shaft surface model, or to define femur geometry, position and orientation, as it is presented in [3] by Cong-Feng Luo et al. The latter can be used to create a 3D solid model for the purpose of studying different aspects of stresses on the femur itself, by a finite element analysis, as presented in [4] by Hsu RWW et al.

Besides that, the 3D curve and the surface model of the femur shaft can be used to analyze the use of different aspects of implants in surgery of the skeletal system.

1.4.

The methods for developing femur anatomical axis are presented and adequately described by Cong-Feng Luo in [2], and Morland JR et al. in [5]. These methods use two points for anatomical axis definition. One point is defined as the center of the femur shaft, while other can be the center of the knee, or the point which is 10 cm away from the surface of knee joint, midway between the medial and lateral surfaces [2]. The line created between two points is always linear, thus, it does not follow the shape of the femur shaft in a natural way. Presented methods use more points on the femur shaft for the creation of the 3D curve, and enable creation of a more natural anatomical axis. Of course, a 3D curve created in this manner can have complex shape, but it can be approximated with the linear curve which can be more precise than the line created only through two points. The creation of solid models from data acquired from medical imaging methods (in this case MRI) is well described in [6] by Stephen Fening. The principles described in that thesis, are general principles for geometrical modeling based on medical data, and they can be applied for various types of models creation, as it is the case in this research.

Fig 1. Femur body cross sections for the GCM 5. Creating 3D spline curve using near operator, with gravity center points as reference, Fig 2.

The geometry analysis of the femur shaft included 10 scans of femur samples. Samples were scanned by computer tomography (CT) in the resolution of 0.5mm. The samples were obtained from European adults, intentionally including different gender and age: 4 women samples, both right and left, age 25, 33, 45, 67, 6 men samples, both right and left, age from 22 to 72. It was assumed that this diverse set of samples could present quite a diverse morphology of the very same bone.

Fig 2. 3D spline curve (anatomical axis) for the GCM 6. Extrapolating curve at end points towards the hip and tibia (tangent extrapolation). The result of this process is a 3D spline curve which is actually the model of femur anatomical axis in 3D space. The measuring of three angles is done in AP plane, with projected anatomical and mechanical axis. AN angle is measured between the projected neck axis and the line tangent to the anatomical axis projection in AP plane. AM angle is measured between the projected mechanical axis and the line tangent to the anatomical axis in the point of its intersection with the mechanical axis. DC angle is measured between the tangential line of distal femur and the projected anatomical axis, Fig 3. To confirm that this method is usable, the procedure is performed on ten femur specimens. The values for three defined angles are presented in the Table 1. Data in Table 1. show that angles are in the appropriate range (compared to study in [2]). Conclusion follows that this is an adequate procedure for creation of the femurs anatomical axis. For some bone models there is a possibility for vast angle(s) deviation; however, this is usually the case when a bone model is inadequate,

2.1.

This method uses same principle as the one described in [2], although with some differences. Instead of using only two points for anatomical axis creation, more points are used in this method. These points are gravity centers of the femurs body cross-sections, Fig 1. The procedure for creating anatomy axis of the femur is somewhat complex, and contains several steps, which are: 1. Creating basic RGEs (Referential Geometrical Entities) on the femur model. This procedure is described in [1] in more detail, 2. Creating plane of intersection (POI) which is plane normal to the AP (Anterior Posterior) plane. The process of creating AP plane is explained in [1], 3. Creating femurs body cross sections, which are cross sections between planes parallel to POI and femurs polygonal model, Fig 1, 2,

1

Nikola Vitkovi, University of Ni, Faculty of Mechanical Engineering, A. Medvedeva 14. vitko@masfak.ni.ac.rs

perhaps due to: bone illness, wrong input data, osteoporosis, etc.

Fig 3. Adequate Femur dimensions (angles) defined on the femur polygonal model Table 1. Angle values for different femur models (GCM) Angle\Femur 1 2 3 4 5 6 7 8 9 AN AM DC 127.1 8.36 81 129 7.61 80.54 127 7.86 82.22 127 8 78.96 126 3.4 80.86 124.9 7.8 79.9 127.2 8 79.7 126.4 7.6 82 127.20 7.56 80.33

2.2.

This method uses a different procedure for defining femurs anatomical axis than standard methods do, as it is described in [1-3, 5]. Generally, the idea for this procedure emanated from the CPM method when cross sections geometry was analyzed. The analysis shows that topology and geometry of cross section curves are very similar to the deformable ellipsis, Fig2. Using that as a starting point for analysis, one can say that cross sections can be projected into two normal planes. These planes contain axes of ellipse, and they are normal to the cross section plane. In the normal plane, cross section is projected as a line, which is actually the axis of ellipse. Middle point of the line is actually the center of ellipse, and end points are the end points of the ellipse axes in appropriate directions, Fig 4. The procedure for this method is: 1. Defining position and orientation for the plane of intersection (POI). This plane is one of the initial planes (PX, PY, PZ) of the imported polygonal model. 2. Creating femurs body cross sections, which are cross sections between planes parallel to POI and femurs polygonal model, Fig 4, 3. Projecting cross section curves to the two perpendicular planes, 4. Finding middle points of the projected curves (lines), 5. Creating 2D spline curves in the normal planes using near or through operator (which depends on quality of curves) with middle points as reference, Fig 4, 6. Extrapolating 2D curves in tangent directions, Fig 5, 7. Creating surfaces as extended 2D spline curves in directions normal to the perpendicular planes, Fig 5,

1

Nikola Vitkovi, University of Ni, Faculty of Mechanical Engineering, A. Medvedeva 14. vitko@masfak.ni.ac.rs

Table 2. shows that angles are in the adequate range, with some deflections (compared to study in [1]). Conclusion follows, that this method is appropriate for anatomical axis creation.

Nikola Vitkovi, University of Ni, Faculty of Mechanical Engineering, A. Medvedeva 14. vitko@masfak.ni.ac.rs

Table 2. Angle values for different femur models (CPM) Angle\Femur 1 2 3 4 5 AN AM DC 129.93 6.36 78.27 131.14 8.78 79.4 126.93 11.21 79.47 137.56 8.85 78.12 133.59 5.94 78.31

7 127.2 8 79.7

8 126.4 7.6 82

Table 1. and Table 2. show different values for defined angles of ten femurs. It can be seen from the tables, that values are in good range, but there are some deviations. For example in Table 2, there is a major digression in AN angle, 137.56 (CPM). This kind of digression can occur with some femurs due to: a defective femur model, an unhealthy or a deformed femur, etc. Thats why arithmetic mean is used for calculating angle values, since it can describe general case, and not an individual occurrence. According to the measurement results (Table 3.), a conclusion follows that GCM method has an advantage in Anatomical axis Neck axis angle, and in Distal Condylar Angle (but much less difference compared to the Anatomical axis Neck axis angle). The angle between Anatomical axis and Mechanical axis has a similar value in either method. The general conclusion follows that both methods can be applied. However, if precision is the most important condition, then the first method is a better choice, while if the speed of creation is the main factor, then the second method ought to be used (there is no need for RGEs definition, which is a time consuming process). Table 3. Angle mean values for GCM and CPM Angle \ Method GCM CPM AN 127.10 129.78 AM 7.26 8.20 DC 80.41 79.38

project (Virtual Human Osteoarticular System and its Application in Preclinical and Clinical Practice) is sponsored by the Ministry of Science and Technology of the Republic of Serbia - project id III 41017 for the period of 2011-2014.

REFERENCES

[1] Stojkovic, M., Trajanovic, M., Vitkovic, N., Milovanovic, J., Arsic, S., Mitkovic, M. (2009) Referential Geometrical Entities for Reverse Modeling of Geometry of Femur, Vip Image 2009, Porto, Portugal. [2] Cong-Feng, Luo. (2004) Reference axis for reconstruction of the knee, The Knee, Vol.11, No 4, pp 251 257 [3] Cong-Feng, Luo., Koshino, T., Takeuchi, R., Saito T. (2001) Reliability of the transepicondylar line as a parameter of femoral axial alignment, Journal of Orthopaedic Science, Vol. 6, No 5, pp 373 377. [4] Hsu, RWW., Himeno, S., Conventry, MB., Chao, EY. (1990) Normal axial alignment of the lower extremity and load-bearing distribution at the knee, Clinical Orthopaedics and Related Research, Vol. 255 pp 215227. [5] Morland, JR., Bassett, LW., Hanker, GJ. (1987) Radiographic analysis of the axial alignment of the lower extremity, Journal of Bone and Joint Surgery, Vol. 69, No 5, pp 745-749. [6] Fening, S. (2003) The creation of solid models of the human knee from Magnetic resonance images, Doctor thesis, The faculty of the Fritz J. and Dolores H. Russ College of Engineering and Technology of Ohio University, pp 41 [7] Kharwadkara, N., Kent, R.E., Shararab, K.H., Naiquec, S. (2006) 5 to 6 of distal femoral cut for uncomplicated primary total knee arthroplasty : Is it safe?, The Knee, Vol.13, No 1, pp 57 - 60 [8] Dargel, J., Joern, M., Feiser, J., Ivo, R., Koebke, J. (2010) Human Knee Joint Anatomy Revisited: Morphometry in the Light of Sex-Specific Total Knee Arthroplasty, Journal of Arthroplasty, Vol. 26 , No 3, pp 346 - 353 [9] William, M., Boyle, J., Clark, L., Krackow, Kenneth A. (2005) The Variability of Intramedullary Alignment of the Femoral Component During Total Knee Arthroplasty, Journal of Arthroplasty ,Vol. 20, No 1, pp 25 - 28

4. CONCLUSION

The presented research describes a new approach that will help to clearly comprehend the geometry of the femurs shaft region (especially the cross section geometry) and, therefore, the geometry of the femur, too. Furthermore, this can improve the design of new implants, taking into consideration their anatomical landmarks, structure and distribution of their bony tissue, and stresses. Finally, the new way of looking at femur shaft can improve the surgery preparation and make it more efficient [7-9]. The methods described in this paper will be tested on more femur specimens, and this does not imply only the amount of specimens, yet, their more comparative values (dimensions), different geographical region, various age groups, etc,. The main reason for further testing is the possibility for creation of one universal method for femur anatomical axis definition, which will produce accurate results regardless of the input data.

ACKNOWLEDGEMENT

The paper presents a case that is a result of application of multidisciplinary research in the domain of bioengineering in real medical practice. The research

CORRESPONDENCE

Nikola VITKOVI, M.Sc. in Mechanical Engineering, University of Ni, Faculty of Mechanical Engineering in Ni, Aleksandra Medvedeva 14, Ni, Serbia, vitko@masfak.ni.ac.rs.

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