Activity 9 EFFECTIVE MATERIALS MANAGEMENT A.

PROCUREMENT

Reading: ASHP Guideline for Selecting Pharmaceutical Manufacturers and Distributors 1. Show a flowchart of the Purchasing procedure for drugs and pharmaceutical products in the hospital.
Requisitions (Pharmacy)

Purchase (purchasing)

Shipments

received

distibuted

problems: shortages, over/under shipments, outdated or deteriorated meds

invoice for payment (Accounting)

checked & stored for future use (Inventory control)

prescribed

product recall receipt

review

Figure 1. Purchasing procedure flowchart 2. Describe Record Keeping procedures and Receiving Control procedures for pharmacy stock.

Record Keeping Procedures -include budget reports, productivity and workload documents, purchase orders, inventory, receiving and dispensing reports and controlled substances and alcohol records. - Record keeping procedures are done to meet government regulations, standards of practice requirements, accreditation standards, hospital policies and management information requirements. 1. Dangerous drugs, biologic and medical device records must be kept for three years. 2. Three-year storage of prescription records 3. All records of controlled substances must be maintained for two years. Receiving Control Procedures -role that can be filled by the pharmacy technician 1. Check the shipping address 2. Check the outside package for visible signs of damage to the carton or contents. Note any damage on the receiving document. 3. Look for any shipping documents and determine if special handling is required. 4. Carefully open the package and check each item for breakage. 5. Check each item for expiration date. 6. Verify the order received against a copy of the purchase order. 7. Refer any order discrepancies to the supervising pharmacist.

3. List down Sample Drug Products with the corresponding prescribed storage condition. (Give the Generic Name and a representative Brand Name) Drug Product 1. Carbocisteine (Solmux cap) 2. Naproxen Na (Flanax tab) 3. Domperidone (Motilium tab) 4. Digoxin (Lanoxin tab) Prescribed Storage Condition Store at temperature not exceeding 30oC Store at temperature not exceeding 30oC. Protect from heat. Store at temperature between 15oC to 30oC. Store at temperature not exceeding

5. Lactulose (Duphalac syrup) 6. Salbutamol (Ventolin inhaler)

25oC. Store at temperature not exceeding 25oC in a cool, dry place. Special precautions for storage: Replace the mouthpiece, cover firmly and snap it into position. Store at temperatures not exceeding 30C. Protect from frost and direct sunlight. As with most inhaled medications in aerosol canister, the therapeutic effect of this medication may decrease when the canister is cold. The canister should not be broken, punctured or burnt, even when apparently empty. Store at temperatures not exceeding 30C. Store in a dry place at room temperature not exceeding 25C. Do not freeze. Store at temperature not exceeding 25C. Keep dry. Bottles of tablets should be kept tightly closed and moisture-proof containers used for dispensing. The reconstituted suspension should be stored and kept in a refrigerator (2-8C) and used within 7-10 (maximum days). Do not freeze. Amikin requires no refrigeration. It is stable at controlled room temperature (28-32C) until expiration date indicated on package.

7. Citicholine (Cholinerv ampule) 8. Mupirocin (Bactroban cream) 9. Co-amoxiclav (Augmentin susp.)

10. Amikacin (Amikin vial)

On the label Means Do not store over 30 C from +2 C to +30C Do not store over 25 C from +2 C to +25C Do not store over 15 C from +2 C to +15C Do not store over 8 C from +2 C to +8C Do not store below 8 C from +8 C to +25C Protect from moisture no more than 60% relative humidity

in normal storage conditions; to be provided to the patient in a moistureresistant container. Protect from light to be provided to the patient in a light-resistant container. 2

Medical and Therapeutic Journals Annals of Internal Medicine British Medical Journal Journal of the American Medical Association Lancet New England Journal of Medicine Drug and Toxicology Information and Pharmacology Journals British Journal of Clinical Pharmacology Clinical Pharmacology and Therapeutics European Journal of Clinical Pharmacology Human and Experimental Toxicology Journal of Toxicology and Clinical Toxicology Medical Toxicology and Adverse Drug Experience

Pharmacy Journals American Journal of Hospital Pharmacy Annals of Pharmacotherapy Clinical Pharmacy DICP-Annals of Pharmacotherapy Journal of Clinical and Hospital Pharmacy Journal of Clinical Pharmacy and Therapeutics Pharmaceutical Journal UK Journals in Specific Areas American Journal of Emergency Medicine Annals of Emergency Medicine British Journal of Obstetrics and Gynaecology Critical Care Medicine Journal of Antimicrobials and Chemotherapy Journal of Infectious Diseases Journal of Paediatrics and Child Health

Essential Drugs Lists and Therapeutic Formularies British National Formulary, updated every six months Essential Drugs List for Zimbabwe, Ministry of Health, Republic of Zimbabwe (1994) The WHO Model Lists of Essential Drugs: The Use and Selection of Drugs. Technical Report Series 615, 641, 722, 770, 850 (1977, 1979, 1983, 1985, 1988, 1992, 1995), World Health Organization, Geneva WHO Model Prescribing Information: Drugs Used in Anesthesia, Parasitic Diseases, Mycobacterial Diseases, Sexually Transmitted Diseases,Skin Diseases