Title: Study on influence of size and surface properties of silica nanobeads in performance of optical sensors Authors & affiliations:

Aleksandar Szchenyi , Barbara Horvth, Sndor Kunsgi-Mt, Barna Kovcs University of Pcs, Faculty of Natural Sciences, Institute of Chemistry, Department of General and Physical Chemistry, PCS, Hungary

Abstract:

(Your abstract must use Normal style and must fit in this box. Your abstract should be no longer than 300 words. The box will expand over 2 pages as you add text/diagrams into it.)

The silica nanoparticles (NPs) are widely used in many different applications such as substrate for label dye, chemical nanosensors for intracellular sensing or drug delivery. They are biocompatible, easily functionalizable and they provide stable matrix for the applications mentioned above. In this work we present our results on the synthesis of modified surface silica NPs used for optical chemical sensors. The NPs have been synthesized by modified Stber method [1]. Influence of tetraethoxysilane (TEOS) and ORMOSIL precursors concentration and their ratio on the size, morphology, stability of the synthesized particles have been studied, while all other parameters are kept constant. During the synthesis ORMOSIL precursors with different polarity or functional group have been used: methyltriethoxysilane (MTES), ethyltriethoxysilane, propyltriethoxysilane and in some cases n-octiltriethoxysilane, phenyltriethoxysilane, 3-aminopropyltriethoxysilane and vinyltriehoxysilane. The resulting NPs have been characterized with TEM, SEM, DLS regarding size and shape. The thermal stability has been examined with TGA and DTA.
300

Size of the nanoparticles vs TEOS concetration

250 Particle size [nm] 200 150 100 50 0 0 20 40 60 80 CTEOS [M] 100 120 140 160

30 25 Particle size [nm] 20 15 10 5 0 0

Size of the nanoparticles vs MTES content (CTEOS=34M)

MTES [n/n %]

The modified Stber method has been used for synthesis of indicator doped NPs. During the synthesis well known pH sensitive fluorescein derivatives [2] were added to the precursor solution. The pH sensing properties of the resulting NPs have been examined, and their sensor performance has been evaluated as a function of the size and surface modifications of NPs. [1] Stber, W.; Fink, A.; Bohn E. J. Colloid Interface Sci. 1968, 26, 62-69. [2] Bernhard M. Weidgans, Ph.D. thesis 2004

Important notes: Do NOT write outside the grey boxes. Any text or images outside the boxes will be deleted. Do NOT alter the structure of this form. Simply enter your information into the boxes. The form will be automatically processed if you alter its structure your submission will not be processed correctly.