Material Safety Data Sheet

ACC# 01188

Phenol, Reagent ACS

Section 1 - Chemical Product and Company Identification

MSDS Name: Phenol, Reagent ACS Catalog Numbers: AC417170000, AC417170250, AC417175000 Synonyms: Carbolic acid; Phenylic acid; Hydroxybenzene; Monohydroxybenzene; Phenyl hydroxide Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ 07410 For information in North America, call: 800-ACROS-01 For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# 108-95-2 Phenol Chemical Name Percent ca.100 EINECS/ELINCS 203-632-7

Hazard Symbols: T Risk Phrases: 34 24/25

Section 3 - Hazards Identification

EMERGENCY OVERVIEW
Appearance: colourless. Flash Point: 79 deg C. Danger! Corrosive. May cause central nervous system effects. May cause liver and kidney damage. Harmful if swallowed or absorbed through the skin. May be harmful if inhaled. Combustible liquid and vapor. May cause central nervous system depression. Causes eye and skin burns. May cause severe respiratory tract irritation with possible burns. May cause severe digestive tract irritation with possible burns. This substance has caused adverse reproductive and fetal effects in animals. Target Organs: Kidneys, central nervous system, liver. Potential Health Effects Eye: Contact with liquid or vapor causes severe burns and possible irreversible eye damage. May cause chemical conjunctivitis and corneal damage. Skin: Harmful if absorbed through the skin. Direct skin contact results in white, wrinkled discoloration, followed by severe burns. Phenol solutions may be absorbed through the skin ra pidly to cause systemic poisoning and possible death. Ingestion: Harmful if swallowed. May cause severe and permanent damage to the digestive tract. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause perforation of the digestive tract. Causes digestive tract burns with immediate pain, swelling of the throat, convulsions, and possible coma.

Inhalation: Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. May be fatal if exposed to high concentrations. Aspiration may lead to pulmonary edema. May also cause pallor, loss of appetite, nausea, vomiting, diarrhea, weakness, darkened urine, headache, sweating, convulsions, cyanosis, unconsciousness, fatigue, pulmonary edema and coma. Inhalation at high concentrations may cause CNS depression and asphixiation. Chronic: Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. May cause liver and kidney damage. May cause reproductive and fetal effects. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects. Repeated skin contact may cause dermatitis with dark pigmentation of the skin. Animal studies have reported the development of tumors.

Section 4 - First Aid Measures

Eyes: Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes). Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure. SPEEDY ACTION IS CRITICAL! Destroy contaminated shoes. Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Notes to Physician: Persons with liver or kidney disease should not be exposed to phenol for any length of time. Antidote: Activated charcoal, followed by cathartic, may be preferred to ipecac induced emesis or lavage in decontamination of the GI tract and preventing systemic absorption of phenol.

Section 5 - Fire Fighting Measures

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated. Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire.

Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the

Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Section 7 - Handling and Storage

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)

Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits
Chemical Name Phenol ACGIH 5 ppm TWA; skin potential for cutaneous absorption NIOSH OSHA - Final PELs 5 ppm TWA; 19 mg/m3 5 ppm TWA; 19 mg/m3 TWA 250 ppm IDLH TWA

OSHA Vacated PELs: Phenol: 5 ppm TWA; 19 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear neoprene gloves, apron, and/or clothing. Selection of specific glove materials should be based on your conditions of use in your application in consultation with your Safety Officer and manufacturer's glove recommendations. Many factors influence the determination of proper glove material such as permeation rates and break through time. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Section 9 - Physical and Chemical Properties

Physical State: Liquid Appearance: colourless Odor: Sweet and tarry odor. pH: Not available. Vapor Pressure: 0.35 mm Hg @ 25 deg C Vapor Density: 3.2 Evaporation Rate:<0.01 (butyl acetate=1)

Viscosity: Not available. Boiling Point: 192 deg C @ 760.00 mmHg Freezing/Melting Point:43 deg C Autoignition Temperature: 605 deg C ( 1,121.00 deg F) Flash Point: 79 deg C ( 174.20 deg F) Decomposition Temperature:Not available. NFPA Rating: (estimated) Health: 4; Flammability: 2; Reactivity: 0 Explosion Limits, Lower:1.30 vol % Upper: 9.50 vol % Solubility: Soluble. Specific Gravity/Density:1.0600g/cm3 Molecular Formula:C6H6O Molecular Weight:94.11

Section 10 - Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, ignition sources, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents, acids, isocyanates, acetaldehyde, nitrides (e.g. potassium nitride, sodium nitride), calcium hypochlorite, peroxomonosulfuric acid, nitrobenzene, sodium nitrite, aluminum chloride, peroxydisulfuric acid, 1,3-butadiene, boron trifluoride diethyl ether. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#: CAS# 108-95-2: SJ3325000 LD50/LC50: CAS# 108-95-2: Draize test, rabbit, eye: 5 mg Severe; Draize test, rabbit, skin: 500 mg/24H Severe; Draize test, rabbit, skin: 100 mg Mild; Inhalation, mouse: LC50 = 177 mg/m3; Inhalation, rat: LC50 = 316 mg/m3; Oral, mouse: LD50 = 270 mg/kg; Oral, rat: LD50 = 317 mg/kg; Skin, rabbit: LD50 = 630 mg/kg; Skin, rat: LD50 = 669 mg/kg;<br. Carcinogenicity: CAS# 108-95-2: ACGIH: A4 - Not Classifiable as a Human Carcinogen IARC: Group 3 carcinogen Epidemiology: Administration onto the skin, mouse: TDLo = 16 gm/kg/40W-I (Tumorigenic - Carcinogenic by RTECS criteria - S kin and Appendages - tumors). Teratogenicity: Oral, rat: TDLo = 1200 mg/kg (female 6-15 day(s) after conception) Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus).; Oral, mouse: TDLo = 4 gm/kg (female 6-15 day(s) after conception) Specific Developmental Abnormalities - musculoskeletal system. Reproductive Effects: Oral, rat: TDLo = 300 mg/kg (female 6-15 day(s) after conception) Fertility - post-implantation mortality (e.g. dead and/or resorbed implants

per total number of implants). Neurotoxicity: No data available. Mutagenicity: Mutation Test Systems - not otherwise specified: Human, HeLa cell = 17 mg/L.; DNA Inhibition: Human, HeLa cell = 1 mmol/L.; Mutation Test Systems - not otherwise specified: Human, Lymphocyte = 5 umol/L.; Sister Chromatid Exchange: Human, Lymphocyte = 5 umol/L. Other Studies: Standard Draize Test: Administration onto the skin (rabbit) = 500 mg/24H (Severe). Standard Draize Test: Administra tion into the eye (rabbit) = 5 mg (Severe).</br.

Section 12 - Ecological Information

Ecotoxicity: Water flea Daphnia: EC50=12 mg/l; 48-hour; CAS# 108-95-2: Unspecified flea Daphnia: EC50=4.0 mg/l; 96-hour; CAS# 108-95-2: Unspecified Fathead Minnow: LC50 > 50 mg/l; 1 Hr; CAS# 108-95-2 Static @ 18-22C Fathead Minnow: TLm = 41 mg/L; 48-hour; CAS# 108-95-2: Flow-through @ 15C Bluegill/Sunfish: TLm = 19 / 5.7 mg/L; 96 Hr; CAS# 108-95-2: Flow-through If released to the environment, phenol's primary removal mechanism is biodegradation which is generally rapid (days). If phenol is released to soil, it will readily leach and biodegrade. The biodegradation in soil is generally rapid with half-lives of under 5 days even in subsurface soils. Environmental: Phenol does not bioconcentrate in aquatic organisms. In the atmosphere, phenol occurs as a vapor and reacts with photochemically-produced hydroxyl radicals resulting in a half-life of approximately 15 hours. During the nighttime, it reacts with nitrate radicals with a resulting half-life of 12 minutes. Phenol has also been shown to be readily removed from the atmosphere by rain. Physical: No information available. Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: CAS# 108-95-2: waste number U188.

Section 14 - Transport Information

US DOT Shipping Name: PHENOL,SOLID Hazard Class: UN Number: 6.1 UN1671 IATA RID/ADR IMO Canada TDG PHENOL 6.1(9.2) UN1671 II

Packing Group: II

Section 15 - Regulatory Information

US FEDERAL
TSCA CAS# 108-95-2 is listed on the TSCA inventory.

Health & Safety Reporting List CAS# 108-95-2: Effective date: June 1, 1987; Sunset Date: June 1, 1997 Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. SARA Section 302 (RQ) CAS# 108-95-2: final RQ = 1000 pounds (454 kg) Section 302 (TPQ) CAS# 108-95-2: TPQ = 500/10,000 pounds; RQ = 1000 pounds SARA Codes CAS # 108-95-2: acute, chronic, flammable. Section 313 This material contains Phenol (CAS# 108-95-2, 100%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. Clean Air Act: CAS# 108-95-2 is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act: CAS# 108-95-2 is listed as a Hazardous Substance under the CWA. CAS# 108-95-2 is listed as a Priority Pollutant under the Clean Water Act. CAS# 108-95-2 is listed as a Toxic Pollutant under the Clean Water Act. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE CAS# 108-95-2 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 34 Causes burns. R 24/25 Toxic in contact with skin and if swallowed. Safety Phrases: S 1/2 Keep locked up and out of reach of children. S 28 After contact with skin, wash immediately with... S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Material Data Safety Sheet (MSDS): Acetic Acid

1. Product Identification 7. Handling and Storage 8. Exposure Controls/Personal 2. Composition Protection 9. Physical and Chemical 3. Hazards Identification Properties 4. First Aid Measures 10. Stability and Reactivity 5. Fire Fighting Measures 11. Toxicological Information 6. Accidental Release Measures 12. Ecological Information 13. Disposal Considerations 16. Other Information

Note: This information sheet has been re-formatted for better clarity by the Department of Earth Sciences. Some of the data such as information on shipping and weapons treaties were intentionally left out. If you want to look at the complete MSDS, you can either check one of the hardcopy versions in the Department, contact the manufacturer, or check one of the various Web-based databases such as those compiled by BU's Office of Environmental Health & Safety (www.bu.edu/ehs/msds/index.htm). Return to MSDS Index 1. Product Identification ACETIC ACID, GLACIAL MSDS Number: A0326 --- Effective Date: 09/24/97 Synonyms: Acetic acid, methane carboxylic acid; ethanoic acid CAS No.: 64-19-7 Molecular Weight: 60.05 Chemical Formula: CH3COOH
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2. Composition/Information on Ingredients

Ingredient

CAS #

Percent

Hazardous?

Acetic Acid Top of Page MSDS Index

64-19-7

100

Yes

3. Hazards Identification Emergency Overview -------------------------POISON! DANGER! CORROSIVE. LIQUID AND MIST CAUSE SEVERE BURNS TO ALL BODY TISSUE. MAY BE FATAL IF SWALLOWED. HARMFUL IF INHALED. INHALATION MAY CAUSE LUNG AND TOOTH DAMAGE. FLAMMABLE LIQUID AND VAPOR. J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience) ---------------------------------------------------------------------------------------------------------Health Rating: 2 - Moderate Flammability Rating: 2 - Moderate Reactivity Rating: 2 - Moderate Contact Rating: 3 - Severe (Corrosive) Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER Storage Color Code: White Stripe (Store Separately) ---------------------------------------------------------------------------------------------------------Potential Health Effects ---------------------------------Inhalation: Inhalation of concentrated vapors may cause serious damage to the lining of the nose, throat, and lungs. Breathing difficulties may occur. Neither odor nor degree of irritation are adequate to indicate vapor concentration. Ingestion: Swallowing can cause severe injury leading to death. Symptoms include sore

throat, vomiting, and diarrhea. Ingestion of as little as 1.0 ml has resulted in perforation of the esophagus. Skin Contact: Contact with concentrated solution may cause serious damage to the skin. Effects may include redness, pain, skin burns. High vapor concentrations may cause skin sensitization. Eye Contact: Eye contact with concentrated solutions may cause severe eye damage followed by loss of sight. Exposure to vapor may cause intense watering and irritation to eyes. Chronic Exposure: Repeated or prolonged exposures may cause darkening of the skin, erosion of exposed front teeth, and chronic inflammation of the nose, throat, and bronchial tubes. Aggravation of Pre-existing Conditions: Persons with pre-existing skin disorders or eye problems, or impaired respiratory function may be more susceptible to the effects of the substance.
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4. First Aid Measures Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician. Ingestion: DO NOT INDUCE VOMITING! Give large quantities of water or milk if available. Never give anything by mouth to an unconscious person. Get medical attention immediately. Skin Contact: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Call a physician. Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

Top of Page MSDS Index

5. Fire Fighting Measures Fire: Flash point: 40C (104F) CC Autoignition temperature: 427C (801F) Flammable limits in air % by volume: lel: 4.0; uel: 16.0 Flammable Liquid and Vapor! Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Vapors can flow along surfaces to distant ignition source and flash back. Contact with strong oxidizers may cause fire. Reacts with most metals to produce hydrogen gas, which can form an explosive mixture with air. Fire Extinguishing Media: Water, dry chemical, foam or carbon dioxide. Water spray may be used to keep fire exposed containers cool. Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved selfcontained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Water may be used to flush spills away from exposures and to dilute spills to nonflammable mixtures. Water diluted acid can react with metals to form hydrogen gas.
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6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Use water spray to dilute spill to a nonflammable mixture. Contain and recover liquid when possible. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Use nonsparking tools and equipment. Do not use combustible materials, such as saw dust. Do not flush to sewer! US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802. J. T. Baker NEUTRASORB(tm) or TEAM(tm) 'Low Na+' acid neutralizers are recommended for spills of this product.
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7. Handling and Storage Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Protect from freezing. Store above 17C (63 F). Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.
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MSDS Index

8. Exposure Controls/Personal Protection Airborne Exposure Limits: -OSHA Permissible Exposure Limit (PEL): 10 ppm (TWA). -ACGIH Threshold Limit Value (TLV): 10 ppm (TWA); 15 ppm (STEL). Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details. Personal Respirators (NIOSH Approved): If the exposure limit is exceeded, a full facepiece respirator with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres. Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
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9. Physical and Chemical Properties (Acetic Acid)

Appearance: Odor: Solubility: Density: pH: % Volatiles by volume @ 21C (70F): Boiling Point: Melting Point: Vapor Density (Air=1): Vapor Pressure (mm Hg): Evaporation Rate (BuAc=1): Top of Page MSDS Index Clear, colorless liquid. Strong, vinegar-like. Infinitely soluble. 1.05 2.4 (1.0M solution) 100 118C (244F) 16.6C (63F) 2.1 11 @ 20C (68F) 0.97

10. Stability and Reactivity Stability: Stable under ordinary conditions of use and storage. Heat and sunlight can contribute to instability. Releases heat and toxic, irritating vapors when mixed with water. Acetic acid contracts slightly upon freezing which may cause the container to burst. Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition. May also release toxic and irritating vapors. Hazardous Polymerization: Will not occur. Incompatibilities: Acetic Acid is incompatible with chromic acid, nitric acid, ethylene glycol, perchloric acid, phosphorous trichloride, oxidizers, sodium peroxide, strong caustics, most metals (except aluminum), carbonates, hydroxides, oxides, and phosphates. Conditions to Avoid: Heat, flame, ignition sources, freezing, incompatibles
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MSDS Index

11. Toxicological Information Oral rat LD50: 3310 mg/kg; skin rabbit LD50: 1.06 g/kg; inhalation mouse LC50: 5620ppm/1-hr; investigated as a mutagen, reproductive effector.
NTP Carcinogen Ingredient Known Anticipated IARC Category

Acetic Acid (64-19-7) Top of Page MSDS Index

No

No

None

12. Ecological Information Environmental Fate: When released into the air, this material may be moderately degraded by reaction with photochemically produced hydroxyl radicals. When released into air, this material is expected to have a half-life between 10 and 30 days. When released into water, this material is expected to readily biodegrade. When released into the water, this material is expected to have a half-life between 1 and 10 days. Standard dilution BOD5/TOD = 58% When released into the soil, this material is expected to readily biodegrade. This material is not expected to significantly bioaccumulate. This material has an estimated bioconcentration factor (BCF) of less than 100. Environmental Toxicity: This material is expected to be slightly toxic to aquatic life. The LC50/96-hour values for fish are between 10 and 100 mg/l. For glacial acetic acid: EC50 (wheat fumigation) = 23.3 mg/m3/2-hr, effect: leaf injury LC50 (shrimp) = 100 - 300 mg/l/48-hr

LC50 (fathead minnow) = 88 mg/l/96-hr This material may be toxic to aquatic life.
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13. Disposal Considerations Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Top of Page MSDS Index

16. Other Information NFPA Ratings: Health: 3 Flammability: 2 Reactivity: 0 Label Hazard Warning: POISON! DANGER! CORROSIVE. LIQUID AND MIST CAUSE SEVERE BURNS TO ALL BODY TISSUE. MAY BE FATAL IF SWALLOWED. HARMFUL IF INHALED. INHALATION MAY CAUSE LUNG AND TOOTH DAMAGE. FLAMMABLE LIQUID AND VAPOR. Label Precautions: Do not get in eyes, on skin, or on clothing. Do not breathe vapor or mist. Keep container closed. Use only with adequate ventilation. Wash thoroughly after handling. Keep away from heat, sparks and flame. Label First Aid: In case of contact, immediately flush eyes or skin with plenty of water for at least

15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In all cases get medical attention immediately. Product Use: Laboratory Reagent. Revision Information: MSDS Section(s) changed since last revision of document include: 10. Disclaimer:

iece airline respirator in the positive pressure mode with emergency escape provisions.

Section 9 - Physical and Chemical Properties

Physical State: Liquid Appearance: clear to yellow Odor: strong odor - acrid odor pH: 1.0 Vapor Pressure: 6.8 mm Hg Vapor Density: Not available. Evaporation Rate:Not available. Viscosity: Not available. Boiling Point: 122 deg C Freezing/Melting Point:-42 deg C Autoignition Temperature: Not available. Flash Point: Not available. Decomposition Temperature:Not available. NFPA Rating: (estimated) Health: 3; Flammability: 0; Reactivity: 1 Explosion Limits, Lower:Not available. Upper: Not available. Solubility: Soluble. Specific Gravity/Density:1.41 Molecular Formula:HNO3 Molecular Weight:63.01

Section 10 - Stability and Reactivity

Chemical Stability: Stable. Decomposes when in contact with air, light, or organic matter. Conditions to Avoid: High temperatures, incompatible materials, ignition sources, dust generation, moisture, combustible materials, reducing agents. Incompatibilities with Other Materials: Reducing agents, acids (organic, e.g. acetic acid, benzoic acid, formic acid, methanoic acid, oxalic acid), alcohols and glycols (e.g. butyl alcohol, ethanol, methanol, ethylene glycol), aldehydes (e.g. acetaldehyde, acrolein, chloral hydrate, formaldehyde), amides (e.g. butyramide, diethyltoluamide, dimethyl formamide), amines (aliphatic and aromatic, e.g. dimethyl amine, propylamine, pyridine, triethylamine), azo, diazo, and hydrazines (e.g. dimethyl hydrazine, hydrazine, methyl hydrazine), carbamates (e.g. carbanolate, carbofuran), caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), cyanides (e.g. potassium cyanide, sodium cyanide), dithiocarbamates (e.g. ferbam, maneb, metham, thiram), esters (e.g. butyl acetate, ethyl acetate, propyl formate), ethers (e.g. dioxane, furfuran, tetrahydrofuran (THF)), fluorides (inorganic, e.g. ammonium fluoride, calcium fluoride, cesium fluoride), hydrocarbons (aromatic, e.g. benzene, chrysene, cumen. Hazardous Decomposition Products: Nitrogen oxides. Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information

RTECS#:

CAS# 7697-37-2: QU5775000; QU5900000 CAS# 7732-18-5: ZC0110000 LD50/LC50: CAS# 7697-37-2: Inhalation, rat: LC50 = 67 ppm(NO2)/4H;<br. CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg;<br. Carcinogenicity: CAS# 7697-37-2: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. CAS# 7732-18-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. Epidemiology: No information found. Teratogenicity: No information found. Reproductive Effects: No information found. Neurotoxicity: No information found. Mutagenicity: No information found. Other Studies: See actual entry in RTECS for complete information.</br. </br.

Section 12 - Ecological Information

Ecotoxicity: No data available. No information available. Environmental: Terrestial: During transport through the soil, nitric acid will dissolve some of the soil material, in particular, the carbonate based materials. The acid will be neutralized to some degree with adsorption of the proton also occurring on clay materials. However, significant amounts of acid are expected to remain for transport down toward the ground water table. Upon reaching the ground water table, the acid will continue to move, now in the direction of the ground water flow. Physical: Not expected to biodegrade or bioconcentrate. Other: For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA."

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Shipping Name: NITRIC ACID Hazard Class: UN Number: 8 UN2031 IATA RID/ADR IMO Canada TDG NITRIC ACID 8(9.2) UN2031 II

Packing Group: II

Section 15 - Regulatory Information

US FEDERAL
TSCA CAS# 7697-37-2 is listed on the TSCA inventory. CAS# 7732-18-5 is listed on the TSCA inventory. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. SARA Section 302 (RQ) CAS# 7697-37-2: final RQ = 1000 pounds (454 kg) Section 302 (TPQ) CAS# 7697-37-2: TPQ = 1000 pounds; RQ = 1000 pounds SARA Codes CAS # 7697-37-2: acute, chronic, flammable. Section 313 This material contains Nitric acid (CAS# 7697-37-2, 69 71%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373. Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act: CAS# 7697-37-2 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: CAS# 7697-37-2 is considered highly hazardous by OSHA. STATE CAS# 7697-37-2 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts. CAS# 7732-18-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: OC Risk Phrases: R 35 Causes severe burns. R 8 Contact with combustible material may cause fire. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 Wear suitable protective clothing. S 45 In case of accident or if you feel unwell, seek

medical advice immediately (show the label where possible). S23B Do not breathe fumes. WGK (Water Danger/Protection) CAS# 7697-37-2: 1 CAS# 7732-18-5: No information available. Canada CAS# 7697-37-2 is listed on Canada's DSL List. CAS# 7697-37-2 is listed on Canada's DSL List. CAS# 7732-18-5 is listed on Canada's DSL List. CAS# 7732-18-5 is listed on Canada's DSL List.

2,4,6-Trinitro- Phenol

Section 1 - Chemical Product MSDS Name: Picric Acid Reagent ACS Material Safety Data Sheet Synonym:Trinitrophenol; Picronitric acid; 2,4,6-Trinitrophenol; 2,4,6-Trinitrophenyl; Picronitric aci

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS name:Phenol, 2,4,6-TrinitroCAS:88-89-1 content:ca 100% EINECS:201-865-9

Hazard Symbols: T E Risk Phrases: 2 23/24/25 4 43

Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Risk of explosion by shock, friction, fire or other sources of ignition. Toxic by inhalation, in contact with skin and if swallowed. Forms very sensitive explosive metallic compounds. May cause sensitization by skin contact.

Potential Health Effects Eye: Causes eye irritation. May result in corneal injury. Skin: Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Ingestion: Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause corrosion and permanent tissue destruction of the esophagus and digestive tract. May cause headache. Inhalation: May cause respiratory tract irritation. Material has a low vapor pressure, so exposure to vapor is not likely. Chronic: Prolonged or repeated skin contact may cause dermatitis. May cause kidney injury. Prolonged or repeated exposure may cause yellow staining of the skin and conjunctiva and "yellow vision".

Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.

Wash clothing before reuse. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES General Information: Evacuate area and fight fire from a safe distance. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Exposure to heat may promote violent decomposition. This material is an explosion hazard when exposed to heat, mechanical shock, or friction. This material poses an explosion hazard when dry. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products. Extinguishing Media: Do NOT use carbon dioxide. Do NOT use halogenated agents. Use flooding quantities of water as spray. Cool containers with flooding quantities of water until well after fire is out.

Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Remove all sources of ignition. If the material is dry, explosives experts may be necessary to dispose of the spill. Isolate area and deny entry. Provide ventilation. Evacuate unnecessary personnel.

Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Material is heat, shock and/or friction sensitive. Use care in handling and storage. Loosen closure cautiously before opening. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep away from heat, sparks and flame. Container should be opened by a technically qualified person. Avoid mechanical shock and friction. Dried crystals may be present within threads of screw top containers and present a detonation hazard when opening. If a bottle of picric acid is old and has a metal cap, care must be exercised as highly shock sensitive metal picrates may have formed. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible

substances. Keep away from metals. Material can explode if dry. Do not store on concrete. Separate from organic materials.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 121.00 - 123.00 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: 1.7630g/cm3 Molecular Formula: C6H3N3O7 Molecular Weight: 229.11

Section 10 - STABILITY AND REACTIVITY Chemical Stability: Explodes above 572F (300C) with release of oxides of nitrogen. Conditions to Avoid: High temperatures, mechanical shock, ignition sources. Incompatibilities with Other Materials: Metals, reducing agents, bases, amines, ammonia, concrete (forms friction sensitive calcium picrate). Hazardous Decomposition Products:

Carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 88-89-1: TJ7875000 LD50/LC50: CAS# 88-89-1: Oral, rat: LD50 = 200 mg/kg. Carcinogenicity: Phenol, 2,4,6-Trinitro- - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION Ecotoxicity: Rainbow trout (Salmo gairdneri), LC50=109.6 mg/L/96 hr; American oysters (Crassotrea virginica), LC50=254.9 mg/L/14 hr; Bluegill (Lepomis macrachirus), LC50=193 mg/L/24 hr

Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION IATA Shipping Name: Trinitrophenol Hazard Class: 1.1 UN Number: 0154 Packing Group: II IMO Shipping Name: Trinitrophenol Hazard Class: 1.1 UN Number: 0154 Packing Group: II RID/ADR Shipping Name: Trinitrophenol Hazard Class: 1.1 UN Number: 0154 Packing group: II

Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T E Risk Phrases: R 2 Risk of explosion by shock, friction, fire or other sources of ignition. R 23/24/25 Toxic by inhalation, in contact with skin and if swallowed.

R 4 Forms very sensitive explosive metallic compounds. R 43 May cause sensitization by skin contact. Safety Phrases: S 28 After contact with skin, wash immediately with... S 35 This material and its container must be disposed of in a safe way. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 88-89-1: 2 United Kingdom Occupational Exposure Limits CAS# 88-89-1: OES-United Kingdom, TWA 0.1 mg/m3 TWA CAS# 88-89-1: OES-United Kingdom, STEL 0.3 mg/m3 STEL United Kingdom Maximum Exposure Limits Canada CAS# 88-89-1 is listed on Canada's DSL List. CAS# 88-89-1 is listed on Canada's Ingredient Disclosure List. Exposure Limits CAS# 88-89-1: OEL-AUSTRALIA:TWA 0.1 mg/m3;STEL 0.3 mg/m3;Skin OEL-BELGIUM:TWA 0.1 mg/m3;STEL 0.3 mg/m3;Skin OEL-DENMARK:TWA 0.1 mg/m3;Skin OEL-FINLAND:TWA 0.1 mg/m3;STEL 0.3 mg/m3;Skin OEL-FRANCE:TWA 0.1 mg/m3;Skin OEL-GERMANY:TWA 0.1 mg/m3;Skin

OEL-HUNGARY:TWA 0.1 mg/m3;STEL 0.2 mg/m3;Skin OEL-THE NETHERLANDS:TWA 0.1 mg/m3;Skin OEL-THE PHILIPPINES:TWA 0.1 mg/m3;Skin OEL-POLAND:TWA 0.1 mg/m3 OEL-SWITZERLAND:TWA 0.1 mg/m3;STEL 0.2 mg/m3;Skin OEL-TURKEY:TWA 0.1 mg/m3;Skin OEL-UNITED KINGDOM:TWA 0.1 mg/m3;STEL 0.3 mg/m3;Skin OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV US FEDERAL TSCA CAS# 88-89-1 is listed on the TSCA inventory.