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1. Nitroglycerin Classification: Antianginal ; NITRATE VASODILATOR Indication: Acute angina, Perioperative hypertension, reduction of cardiac workload in acute MI.

Side effects: headache, apprehension, restlessness, weakness, vertigo, dizziness, faintness Nursing Management: Encourage patient not to swallow since it is sublingual. Ask patient if tablet fizzles or burns. 2. Isoket Classification: Antianginal ; Nitrate vasodilator Indication: angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action Side effects: headache, apprehension, restlessness, weakness, vertigo, dizziness, faintness Nursing management: : Encourage patient not to swallow since it is sublingual. 3. Vitamin K Classification: Indication: Anticoagulant-induced prothrombin deficiency caused by coumarin or indanedione derivatives; Prophylaxis and therapy of hemorrhagic disease of the newborn. Side effects: Transient "flushing sensations" and "peculiar"sensations of taste have been observed, as well as rare instances of dizziness, rapid and weak pulse, profuse sweating, brief hypotension, dyspnea, and cyanosis. Pain, swelling, and tenderness at the injection site may occur.

Nursing management: watch for signs of flushing, weakness, tachycardia and hypotension; may progress to shock. Be aware that phytonodione therapy for hemorrhagic disease in infants causes fewer adverse reactions than do other vitamin K analogues. Failure to respond to vitamin K may indicate coagulation defects.

4. Neurobion Classification: Multivitamin (vitamins B1 + B6 + B12)

Indication: Neuritis and neuralgia, especially cervical syndrome, shoulder-arm syndrome, lumbalgia, sciatica, facial paresis. Alcoholic polyneuropathy, Diabetic neuropathy, including impotence due to autonomic neuropathy. Metabolic and neuropathic changes due to pregnancy and oral contraceptives. Drug-induced neuropathies. Supplemental therapy following major surgery or debilitating illness. Side effects: Nausea, constipation, black stools, and diarrhea Nursing Management: 5. Potassium Chloride Classification: Electrolytes and Replacement Solutions Indication: Hypokalemia Side effects: GI ulceration (sometimes with haemorrhage and perforation or with late formation of strictures) following the use of enteric-coated K chloride preparation; hyperkalaemia. Oral: Nausea, vomiting, diarrhoea and abdominal cramps. IV: Pain or phloebitis; cardiac toxicity.

Nursing management: use cautiously in patients with cardiac disease and in those with renal impairment Alert: IV use: Give by infusion only; never give IV push or IM. give slowly as dilute solution; potentially fatal hyperkalemia may result from too-rapid infusion Give oral potassium supplements with extreme caution because different forms deliver varying amounts of potassium. Never switch products without a doctors order. Give oral potassium supplements with extreme caution because different forms deliver varying amounts of potassium. Never switch products without doctors order. make sure powders are completely dissolved before administering Know that enteric-coated tablets are not recommended because of increased potential for GI bleeding and small bowel ulcerations. Know that drug is often used orally with potassium-wasting diuretics to maintain potassium levels. Be aware that sugar free liquid is available; use if tablet or capsule passage is likely to be delayed, such as GI obstruction. Have patients sip slowly to minimize GI irritation.

6. Sodium Chloride Classification: electrolyte Indication: Dehydration,Electrolyte disorder, Hyponatraemia, Leg cramps, Sodium depletion, and can also be given in adjunctive therapy as an alternative drug of choice in Diabetic ketoacidosis, Poisoning.

Side effects: hypernatremia, hypopotassemia, acidosis. Fluid and solute overload leading to dilution of serum electrolyte level, CHF, overhydration, acute pulmonary edema Nursing management: Monitor electrolytes, ECG, liver and renal function studies. Note level of consciousnessc. Assess the heart and lung sounds. Observe S&S of hypernatremia, flushed skin, elevated temperature, rough dry tongue, and edema. Monitor VS and I&Of. Assess urine specific gravity and serum sodium levels 7. Paracetamol Classification: Anti-pyretic Indication: Ear pain, Fever,Headache, Malaise, Migraine, Mild to moderate pain, Pain, Postvaccine reaction, Short-bowel syndrome, Tobacco amblyopia and leber's optic atrophy, Toothache. Side effects: Bronchospasm, Blood dyscrasias, Liver damage, Skin rashes, GI adverse effects, Hepatic necrosis, Liver failure. Nursing management: Check that the patient is not taking any other medication containing paracetamol. - For children who may refuse medicine off a spoon try using a medicine syringe to squirt liquid slowly into the side of the child's mouth or use soluble paracetamol mixed with a drink. - Some children may be happy to take one paracetamol product but dislike the taste of another. - There are no known harmful effects when used during pregnancy. - Small amounts may pass into breast milk. However, there are no known harmful effects when used by breastfeeding mothers. - Alcohol increases the risk of liver damage that can occur if an overdose of paracetamol is taken. The hazards of paracetamol overdose are greater in persistent heavy drinkers and in people with alcoholic liver disease.

8. Ibuprofen Classification: non-steroidal analgesic, antipyretic and anti inflammatory agent Indication: Cystic fibrosis, Fever,Juvenile chronic arthritis, Migraine, Mild to moderate pain,Musculoskeletal pain, Nausea and vomiting (palliative care),Osteoarthritis, Pain, Post operative analgesia, Rheumatoid arthritis,Severe pain and tenderness in benign fibrocystic breast disease,Toothache Side effects: Vomiting, Peptic ulceration, Hematemesis, Severe gastric pain,

Nursing management: Report blurred vision, ringing, roaring in ears; may indicate toxicity; eye and hearing tests should be done during long-term therapy. Avoid driving, other hazardous activities if drowsiness or dizziness occurs. Report change in urinary pattern, increased weight, edema, increased pain in joints, fever, blood in urine, indicatenephrotoxicity. Therapeutic inflammatory effects may take up to 1 month. Avoid alcohol, NSAIDs, salicylates; bleeding may occur . Use sunscreen to prevent photosensitivity. 9. Celecoxib Classification: NSAID, Analgesic (nonopioid) Indication: Osteoarthritis,Rheumatoid arthritis, Dysmenorrhoea, Pain, Toothache. Side effecs: GI bleeding, Rhinitis, Myalgia, Urinary tract infection, Bronchitis, Pharyngitis Nursing Management: Administer drug with food or after meals if GI upset occurs. Establish safety measures if CNS, visual disturbances occur. Arrange for periodic ophthalmologic examination during long-term therapy. WARNING: If overdose occurs, institute emergency proceduresgastric lavage, induction of emesis, supportive therapy. Provide further comfort measures to reduce pain (eg, positioning, environmental control), and to reduce inflammation (eg, warmth, positioning, rest). 10: Etoricoxib Classification: Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics Indication: Acute gout, Muscle relaxation (rapid onset, short duration). Side effects: Flatulence, Fatigue, Myalgia,Constipation, Dry mouth, Mouth ulcers, Influenza like syndrome, Chest pain, Paresthesias, Dry mouth, Taste disturbanceX, Appetite and weight changes. Nursing management: Caution should be exercised in patients with history of heart, liver, kidney disease, high blood pressure, blood clotting disorder, any allergy, children, elderly, during pregnancy and breast feeding. * Drink adequate fluid to avoid dehydration. * Stop the medication immediately if gastrointestinal lesions occur. * Monitor blood pressure regularly while taking this medication. 11. Myonal Classification: Eperisone hydrochloride Indication: spastic spinal paralysis, , postoperative sequelae (together with cerebrospinal tumor),Cerebrovascular diseases, amyotrophic lateral sclerosis, cervical spondylosis, sequelae to trauma ( head injury, spinal trauma), spinocerebellar degeneration, spinal vascular diseases, cerebral palsy, and further encephalomyelopathies. Side effects: Weakness, sleepiness, lightheadedness

Nursing management:

12. Aspirin Classification: salicylate drug (analgesic, anti-pyretic, anti-inflammatory) Indication: Mild to moderate pain, fever, inflammatory conditions such rheumatic fever, rheumatoid arthritis, osteoarthriti. Side effects: stomach pain, nausea, vomiting, and occult gastrointestinal blood loss Nursing management: Give drug with food or after meals. Do not use to treat chickenpox or flu symptoms without review for Reyes syndrome, a rare but fatal disorder. 13. Clopidogrel bisulfate Classification: Adenosine diphosphate (ADP) receptor antagonist, antiplatelet Indication: Patients at risk for ischemic eventsrecent MI, recent ischemic CVA, peripheral artery disease. Acute coronary syndrome Side effects: Headache, dizziness, hypertension, edema, weakness, syncope, flushing Nursing management: Provide frequent small meals if GI is upset.

14. Ranitidine Classification: Histamine-2 (H2) antagonist Indication: Acute duodenal ulcer, Active and benign gastric ulcer, erosive esophangitis, heart burn, acid indigestion, sour stomach. Side effects: Headache, malaise, dizziness, somnolence, insomnia, vertigo, tachycardia, bradycardia. Nursing management: Give drug with meals and at bed time. Decrease doses in renal and liver failure. .15.Cimetidine

Classification: Histamine-2 (H2) antagonist Indication: Acute duodenal ulcer, Active and benign gastric ulcer, erosive esophangitis, heart burn, acid indigestion, sour stomach. Side effects: dizziness, somnolence, headache, confusion, hallucinations, peripheral neuropathy Nursing management: Give drug with meals and at bed time. Decrease doses in renal and hepatic impairment 16. Tranexamic Acid (Tranylcypromine sulfate) Classification: Antidepressant, MAOI Indication: Migraine, headache, panic disorder, social anxiety disorder, bipolar depression, Alzheimers disease, Parkinsons disease Side effects: dizziness, vertigo, headache, over-activity, hyperreflexia, tremors, muscle twitching, mania, hypomania, memory impairment Nursing Management: Monitor BP and orthostatic BP carefully. 17. Tramadol Classification: Analgesic, opioid analgesic Indication: moderate to severe pain, premature ejaculation, restless leg syndrome Side effects: Sedation, dizziness, vertigo, headache, tachycardia, bradycardia, hypotension Nursing management: Report severe nausea, dizziness, and sever constipation.

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